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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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PINK1 and diabetes mellitus are reported together in 1 article.
Gene
PINK1
- HGNC
- HGNC:14581
16articles
16mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Parkinson disease 10Alzheimer disease 1amyotrophic lateral sclerosis 1breast cancer 1cardiomyopathy 1diabetes mellitus 1multiple sclerosis 1stroke 1
Reported variants (articles · ClinVar status)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Cardioprotective effects of 3-N-Butylphthalide in diabetic cardiomyopathy: focus on balanced mitochondrial dynamics and pyroptosis pathways.
PMID 42086310 | DOI 10.4196/kjpp.25.294 · The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | PINK1 | “Inflammasome and pyroptosis markers (NLRP3, cleaved-caspase-1, ASC, GSDMD-N, IL-1β, LDH) increased, mitophagy (PINK1, Parkin) decreased, and mitochondrial function (ROS up, ATP down) worsened in DCM group.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Diabetic cardiomyopathy (DCM) is a severe complication of diabetes, marked by myocardial dysfunction due to mitochondrial dysfunction and pyroptosis.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | NLRP3 | “Inflammasome and pyroptosis markers (NLRP3, cleaved-caspase-1, ASC, GSDMD-N, IL-1β, LDH) increased, mitophagy (PINK1, Parkin) decreased, and mitochondrial function (ROS up, ATP down) worsened in DCM group.” | 0.98 | hgnc_dict_v1 |
| phenotype | cardiomyopathy | “Cardioprotective effects of 3-N-Butylphthalide in diabetic cardiomyopathy: focus on balanced mitochondrial dynamics and pyroptosis pathways.” | 0.98 | phenotype_alias_lexicon_v2 |