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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
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PON1 and Alzheimer disease are reported together in 1 article.
Gene
PON1
- HGNC
- HGNC:9204
20articles
20mentions
3variants with confirmed gene link
Most co-reported phenotypes (articles)
coronary artery disease 4diabetes mellitus 3familial hypercholesterolemia 2obesity 2Alzheimer disease 1glucose-6-phosphate dehydrogenase deficiency 1sickle cell disease 1stroke 1
Reported variants (articles · ClinVar status)
Phenotype
Alzheimer disease
455articles
455mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Unveiling the Neuroprotective Effect of Paraoxonase 1 in Neurodegenerative Diseases Focusing on Alzheimer's Disease.
PMID 41335160 | DOI 10.1007/s12035-025-05493-1 · Molecular neurobiology · 2025 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | PON1 | “Paraoxonase 1 (PON1) is a hydrolyzing paraoxon enzyme; it prevents the development of oxidative stress damage.” | 0.98 | hgnc_dict_v1 |
| phenotype | Alzheimer disease | “Unveiling the Neuroprotective Effect of Paraoxonase 1 in Neurodegenerative Diseases Focusing on Alzheimer's Disease.” | 0.93 | phenotype_alias_lexicon_v2 |