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PPARGC1A and obesity are reported together in 2 articles.

HGNC
HGNC:9237
5articles
5mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype

Obesity

HPO
HP:0001513
856articles
856mentions
12co-reported genes shown
Most co-reported genes (articles)

Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.

Publications

2 records shown · first 60

Modulatory Role of Moringa Oleifera-Loaded Silver Nanoparticles on UCP1 and PPARGC1A Genes Expression in an Obesity Rat Model.

PMID 41575697 | PMCID PMC13032946 | DOI 10.1007/s12010-025-05511-x · Applied biochemistry and biotechnology · 2026 · 3 validated mentions
TypeEntitySource evidenceConfidenceExtractor
genePPARGC1A“Modulatory Role of Moringa Oleifera-Loaded Silver Nanoparticles on UCP1 and PPARGC1A Genes Expression in an Obesity Rat Model.”0.98hgnc_dict_v1
phenotypeobesity“Modulatory Role of Moringa Oleifera-Loaded Silver Nanoparticles on UCP1 and PPARGC1A Genes Expression in an Obesity Rat Model.”0.98phenotype_alias_lexicon_v2
geneUCP1“Modulatory Role of Moringa Oleifera-Loaded Silver Nanoparticles on UCP1 and PPARGC1A Genes Expression in an Obesity Rat Model.”0.98hgnc_dict_v1

Pumpkin (Cucurbita ficifolia Bouché) extract attenuate the adipogenesis in human mesenchymal stem cells by controlling adipogenic gene expression.

PMID 31048999 | PMCID PMC6486525 | DOI 10.1016/j.sjbs.2018.10.002 · Saudi journal of biological sciences · 2019 · 8 validated mentions
TypeEntitySource evidenceConfidenceExtractor
genePPARGC1A“Chloroform extract treated cells display the down-regulation of ADIPOQ, FABP4, PPARGC1A, CEBPB & LPL and up-regulation of ACACB & CEBPA genes.”0.98hgnc_dict_v1
phenotypeobesity“Prevention and management of obesity through dietary modification is one of the top way to trim down its consequences.”0.98phenotype_alias_lexicon_v2
geneADIPOQ“Chloroform extract treated cells display the down-regulation of ADIPOQ, FABP4, PPARGC1A, CEBPB & LPL and up-regulation of ACACB & CEBPA genes.”0.98hgnc_dict_v1
geneFABP4“Chloroform extract treated cells display the down-regulation of ADIPOQ, FABP4, PPARGC1A, CEBPB & LPL and up-regulation of ACACB & CEBPA genes.”0.98hgnc_dict_v1