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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.

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PRKAG2 and stroke are reported together in 1 article.

Gene

PRKAG2

HGNC
HGNC:9386
3articles
3mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype

Stroke

555articles
555mentions
12co-reported genes shown
Most co-reported genes (articles)

Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.

Publications

1 records shown · first 60

New Insights into Genetic Polymorphisms Influencing the Therapeutic Efficacy and Toxicity of Rivaroxaban.

PMID 42394189 | DOI 10.1002/jcph.70236 · Journal of clinical pharmacology · 2026 · 11 validated mentions
TypeEntitySource evidenceConfidenceExtractor
genePRKAG2“A preliminary effect of polymorphisms in CYP2C19, PRF1, and PRKAG2 on rivaroxaban outcome still needs validation.”0.98hgnc_dict_v1
phenotypestroke“Thromboembolic diseases, including venous thromboembolism and atrial fibrillation-related stroke, represent a prevalent health concern and a risk for mortality and health care costs.”0.98phenotype_alias_lexicon_v2
geneCYP3A4“CYP3A4 and CYP3A5 polymorphisms greatly impacted the pharmacokinetics of rivaroxaban; CYP2J2 polymorphisms were not greatly associated with the clinical outcome.”0.98hgnc_dict_v1
geneCYP3A5“CYP3A4 and CYP3A5 polymorphisms greatly impacted the pharmacokinetics of rivaroxaban; CYP2J2 polymorphisms were not greatly associated with the clinical outcome.”0.98hgnc_dict_v1