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RAF1 and Noonan syndrome are reported together in 1 article.
Gene
RAF1
- HGNC
- HGNC:9829
9articles
9mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Noonan syndrome
8articles
8mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Discovering potential inhibitors of Raf proto-oncogene serine/threonine kinase 1: a virtual screening approach towards anticancer drug development.
PMID 37104027 | DOI 10.1080/07391102.2023.2204380 · Journal of biomolecular structure & dynamics · 2024 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | RAF1 | “Raf proto-oncogene serine/threonine kinase 1 (RAF1 or c-Raf) is a serine/threonine protein kinase crucial in regulating cell growth, differentiation, and survival.” | 0.98 | hgnc_dict_v1 |
| phenotype | Noonan syndrome | “Any disruption or overexpression of RAF1 can result in neoplastic transformation and other disorders such as cardiomyopathy, Noonan syndrome, leopard syndrome, etc.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | cardiomyopathy | “Any disruption or overexpression of RAF1 can result in neoplastic transformation and other disorders such as cardiomyopathy, Noonan syndrome, leopard syndrome, etc.” | 0.98 | phenotype_alias_lexicon_v2 |