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ROS1 and thyroid cancer are reported together in 2 articles.
Gene
ROS1
- HGNC
- HGNC:10261
18articles
18mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Thyroid cancer
216articles
216mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Molecular Genetics of Diffuse Sclerosing Papillary Thyroid Cancer.
PMID 36995892 | DOI 10.1210/clinem/dgad185 · The Journal of clinical endocrinology and metabolism · 2023 · 17 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ROS1 | “Probably pathogenic alterations occurred in 13/19 tumors (68.4%) and included variants in POLE (31.6%), CDKN2A (26%), NF1 (21%), BRCA2 (15.8%), SETD2 (5.3%), ATM (5.3%), FLT3 (5.3%), and ROS1 (5.3%).” | 0.98 | hgnc_dict_v1 |
| phenotype | thyroid cancer | “Molecular Genetics of Diffuse Sclerosing Papillary Thyroid Cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | HRAS | “RESULTS: Three tumors were tested only by Sanger sequencing and were negative for BRAFV600E, HRAS, KRAS, NRAS, TERT promoter, PTEN, and PIK3CA mutations.” | 0.98 | hgnc_dict_v1 |
| gene | KRAS | “RESULTS: Three tumors were tested only by Sanger sequencing and were negative for BRAFV600E, HRAS, KRAS, NRAS, TERT promoter, PTEN, and PIK3CA mutations.” | 0.98 | hgnc_dict_v1 |
Microarray expression profiling identifies genes, including cytokines, and biofunctions, as diapedesis, associated with a brain metastasis from a papillary thyroid carcinoma.
PMID 27822408 | PMCID PMC5088282 · American journal of cancer research · 2016 · 22 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ROS1 | “ROS1, MYBPH, SLC18A3, HP, SAA2-SAA4, CP, CCL20, GFAP, RNU1-120P, DMBT1, XDH, CXCL1, PI3, and NAPSA.” | 0.98 | hgnc_dict_v1 |
| phenotype | thyroid cancer | “Microarray expression profiling identifies genes, including cytokines, and biofunctions, as diapedesis, associated with a brain metastasis from a papillary thyroid carcinoma.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | BRAF | “In this study, we compared whole transcript microarray expression profiles of a BRAF mutant, brain metastasis from a PTC, including its technical replicate (TR), with eight non-brain metastatic PTCs and eight primary brain tumors.” | 0.98 | hgnc_dict_v1 |
| gene | MYBPH | “ROS1, MYBPH, SLC18A3, HP, SAA2-SAA4, CP, CCL20, GFAP, RNU1-120P, DMBT1, XDH, CXCL1, PI3, and NAPSA.” | 0.98 | hgnc_dict_v1 |