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RUNX1 and breast cancer are reported together in 1 article.
Gene
RUNX1
- HGNC
- HGNC:10471
25articles
25mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
leukemia 14Down syndrome 2breast cancer 1diabetes mellitus 1hepatocellular carcinoma 1myocardial infarction 1rheumatoid arthritis 1
Reported variants (articles · ClinVar status)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Interplay between Epigenetic and Transcription Factors Mediating Drug Resistance via Stem Cells in Breast Cancer.
PMID 41476491 | PMCID PMC12750211 | DOI 10.1021/acsomega.5c09485 · ACS omega · 2025 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | RUNX1 | “The maintenance of the stem cell phenotype is mostly driven by stem cell transcription factors (e.g., KLFs, Myc, ZEB2, RUNX1, TWIST1, OCT4, NANOG, FOXO3, SOX2, E2Fs, etc.), which are mediated by epigenetic changes in tumor cells at many levels.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Interplay between Epigenetic and Transcription Factors Mediating Drug Resistance via Stem Cells in Breast Cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | ZEB2 | “The maintenance of the stem cell phenotype is mostly driven by stem cell transcription factors (e.g., KLFs, Myc, ZEB2, RUNX1, TWIST1, OCT4, NANOG, FOXO3, SOX2, E2Fs, etc.), which are mediated by epigenetic changes in tumor cells at many levels.” | 0.98 | hgnc_dict_v1 |
| gene | TWIST1 | “The maintenance of the stem cell phenotype is mostly driven by stem cell transcription factors (e.g., KLFs, Myc, ZEB2, RUNX1, TWIST1, OCT4, NANOG, FOXO3, SOX2, E2Fs, etc.), which are mediated by epigenetic changes in tumor cells at many levels.” | 0.98 | hgnc_dict_v1 |