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SAMHD1 and HIV infection are reported together in 2 articles.
Gene
SAMHD1
- HGNC
- HGNC:15925
8articles
8mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
HIV infection
146articles
146mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells.
PMID 31867020 | PMCID PMC6909011 | DOI 10.3389/fimmu.2019.02889 · Frontiers in immunology · 2019 · 8 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SAMHD1 | “Dual exposure to HSV-2 and HIV-1 gave decreased levels of several HIV-1 restriction factors, especially SAMHD1, TREX1, and APOBEC3G.” | 0.98 | hgnc_dict_v1 |
| phenotype | HIV infection | “HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | TLR2 | “Interestingly, we could not see any involvement of TLR2 or TLR3 nor suppression of infection by IFN-β production.” | 0.98 | hgnc_dict_v1 |
| gene | TLR3 | “Interestingly, we could not see any involvement of TLR2 or TLR3 nor suppression of infection by IFN-β production.” | 0.98 | hgnc_dict_v1 |
The role of SAMHD1 expression and its relation to HIV-2 (Vpx) gene production.
PMID 30202235 | PMCID PMC6128726 | DOI 10.1016/j.jsps.2018.03.005 · Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018 · 2 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SAMHD1 | “The role of SAMHD1 expression and its relation to HIV-2 (Vpx) gene production.” | 0.98 | hgnc_dict_v1 |
| phenotype | HIV infection | “This increases the amount of dNTPs for viral reverse transcription in cytoplasm and HIV infection.” | 0.98 | phenotype_alias_lexicon_v2 |