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SCAP and metabolic syndrome are reported together in 2 articles.
Gene
SCAP
- HGNC
- HGNC:30634
6articles
6mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Metabolic syndrome
141articles
141mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Effect of genetic polymorphisms in SREBF-SCAP pathway on therapeutic response to rosuvastatin in Saudi metabolic syndrome patients.
PMID 29318930 | DOI 10.2217/pgs-2017-0181 · Pharmacogenomics · 2018 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SCAP | “RESULTS & CONCLUSION: No associations of SCAP and SREBF-1a genotypes with baseline lipids but significant associations with lipid reductions were observed.” | 0.98 | hgnc_dict_v1 |
| phenotype | metabolic syndrome | “Effect of genetic polymorphisms in SREBF-SCAP pathway on therapeutic response to rosuvastatin in Saudi metabolic syndrome patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “Effect of genetic polymorphisms in SREBF-SCAP pathway on therapeutic response to rosuvastatin in Saudi metabolic syndrome patients.” | 0.95 | saudi_context_rules_v1 |
Effect of an SNP in SCAP gene on lipid-lowering response to rosuvastatin in Indian patients with metabolic syndrome.
PMID 27885915 | DOI 10.2217/pgs.16.30 · Pharmacogenomics · 2016 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SCAP | “Effect of an SNP in SCAP gene on lipid-lowering response to rosuvastatin in Indian patients with metabolic syndrome.” | 0.98 | hgnc_dict_v1 |
| phenotype | metabolic syndrome | “Effect of an SNP in SCAP gene on lipid-lowering response to rosuvastatin in Indian patients with metabolic syndrome.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | dyslipidemia | “AIM: Statins treat dyslipidemia associated with metabolic syndrome.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | 2386A>G | “SCAP 2386A>G gene polymorphism is a significant predictor of hypolipidemic response.” | 0.82 | literature_variant_regex_v2 |