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SOD3 and obesity are reported together in 2 articles.
Gene
SOD3
- HGNC
- HGNC:11181
11articles
11mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Obesity
- HPO
- HP:0001513
856articles
856mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Antioxidants-Related Superoxide Dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPX), Glutathione-S-Transferase (GST), and Nitric Oxide Synthase (NOS) Gene Variants Analysis in an Obese Population: A Preliminary Case-Control Study.
PMID 33924357 | PMCID PMC8070436 | DOI 10.3390/antiox10040595 · Antioxidants (Basel, Switzerland) · 2021 · 14 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SOD3 | “Six SNPs were significantly more prevalent in obese cohorts: (1) GSTM1 rs1056806*C/T; (2) SOD1 rs2234694*A; (3) SOD2 rs4880*G; (4) SOD3 rs2536512*A; (5) GPX1 rs1800668*A; (6) NOS3 rs1799983*G.” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “Oxidative stress and antioxidants play an important role in obesity etiopathology.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | GSTM1 | “Six SNPs were significantly more prevalent in obese cohorts: (1) GSTM1 rs1056806*C/T; (2) SOD1 rs2234694*A; (3) SOD2 rs4880*G; (4) SOD3 rs2536512*A; (5) GPX1 rs1800668*A; (6) NOS3 rs1799983*G.” | 0.98 | hgnc_dict_v1 |
| gene | SOD1 | “Six SNPs were significantly more prevalent in obese cohorts: (1) GSTM1 rs1056806*C/T; (2) SOD1 rs2234694*A; (3) SOD2 rs4880*G; (4) SOD3 rs2536512*A; (5) GPX1 rs1800668*A; (6) NOS3 rs1799983*G.” | 0.98 | hgnc_dict_v1 |
Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells.
PMID 31978617 | DOI 10.1016/j.bone.2020.115252 · Bone · 2020 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | SOD3 | “In addition, RSV reduced the levels of senescence-associated secretory phenotype (SASP), gene markers associated with senescence (P53, P16, and P21), intracellular ROS levels and increased gene expression of enzymes protecting cells from oxidative damage (HMOX1 and SOD3).” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “An increased BMAT volume is observed in several conditions e.g. obesity, type 2 diabetes, osteoporosis and is known to be associated with bone fragility and increased risk for fracture.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | HMOX1 | “In addition, RSV reduced the levels of senescence-associated secretory phenotype (SASP), gene markers associated with senescence (P53, P16, and P21), intracellular ROS levels and increased gene expression of enzymes protecting cells from oxidative damage (HMOX1 and SOD3).” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “An increased BMAT volume is observed in several conditions e.g. obesity, type 2 diabetes, osteoporosis and is known to be associated with bone fragility and increased risk for fracture.” | 0.93 | phenotype_alias_lexicon_v2 |