Advanced search

Combine gene, variant, phenotype, region and year filters

Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.

Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
About your search

STAT1 and tuberculosis are reported together in 3 articles.

Gene

STAT1

HGNC
HGNC:11362
51articles
51mentions
10variants with confirmed gene link (top 10)
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype

Tuberculosis

405articles
405mentions
12co-reported genes shown
Most co-reported genes (articles)

Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.

Publications

3 records shown · first 60
TypeEntitySource evidenceConfidenceExtractor
geneSTAT1“Interleukin 1B (IL1B), CAPS1, and signal transducer and activator of transcription 1 (STAT1) were identified by intersection out of 22 DE-ATGs discovered by differential expression analysis.”0.98hgnc_dict_v1
phenotypetuberculosis“Identification and Analysis of Autophagy-Related Genes as Diagnostic Markers and Potential Therapeutic Targets for Tuberculosis Through Bioinformatics.”0.98phenotype_alias_lexicon_v2
geneIL1B“Interleukin 1B (IL1B), CAPS1, and signal transducer and activator of transcription 1 (STAT1) were identified by intersection out of 22 DE-ATGs discovered by differential expression analysis.”0.98hgnc_dict_v1
geneCASP1“We found that IL1B, CASP1, and STAT1 are important biomarkers for TB.”0.98hgnc_dict_v1

Novel mutations in genes of the IL-12/IFN-γ axis cause susceptibility to tuberculosis.

PMID 37437430 | DOI 10.1016/j.jiph.2023.06.005 · Journal of infection and public health · 2023 · 8 validated mentions
TypeEntitySource evidenceConfidenceExtractor
geneSTAT1“Flow cytometry was used to detect the surface expressions of IFN-γR1 and IFN-γR2 as well as IL-12Rβ1and IL-12Rβ2 on monocytes and T lymphocytes, respectively.The phosphorylation of signal transducer and activator of transcription 1(STAT1) on monocytes and STAT4 on T lymphocytes were also detected by flow cytometry.”0.98hgnc_dict_v1
phenotypetuberculosis“Novel mutations in genes of the IL-12/IFN-γ axis cause susceptibility to tuberculosis.”0.98phenotype_alias_lexicon_v2
geneSTAT4“Flow cytometry was used to detect the surface expressions of IFN-γR1 and IFN-γR2 as well as IL-12Rβ1and IL-12Rβ2 on monocytes and T lymphocytes, respectively.The phosphorylation of signal transducer and activator of transcription 1(STAT1) on monocytes and STAT4 on T lymphocytes were also detected by flow cytometry.”0.98hgnc_dict_v1
geneCYBB“Sanger sequencing was used to identify mutations in the IL-12Rβ1, STAT1, NEMO, and CYBB genes.”0.98hgnc_dict_v1

A Network-Based Analysis Reveals the Mechanism Underlying Vitamin D in Suppressing Cytokine Storm and Virus in SARS-CoV-2 Infection.

PMID 33362771 | PMCID PMC7756074 | DOI 10.3389/fimmu.2020.590459 · Frontiers in immunology · 2020 · 7 validated mentions
TypeEntitySource evidenceConfidenceExtractor
geneSTAT1“Interestingly, the iRegulone tool identified that "Cluster 1" is under the regulation of transcription factors STAT1, STAT2, STAT3, POU2F2, and NFkB1, collectively referred to as "host response signature network".”0.98hgnc_dict_v1
phenotypetuberculosis“Functional enrichment analysis with NDEx revealed that the "host response signature network" is predominantly associated with critical pathways, including "cytokines and inflammatory response", "non-genomic action of Vitamin D", "the human immune response to tuberculosis", and "lung fibrosis".”0.98phenotype_alias_lexicon_v2
geneSTAT2“Interestingly, the iRegulone tool identified that "Cluster 1" is under the regulation of transcription factors STAT1, STAT2, STAT3, POU2F2, and NFkB1, collectively referred to as "host response signature network".”0.98hgnc_dict_v1
geneSTAT3“Interestingly, the iRegulone tool identified that "Cluster 1" is under the regulation of transcription factors STAT1, STAT2, STAT3, POU2F2, and NFkB1, collectively referred to as "host response signature network".”0.98hgnc_dict_v1