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TBK1 and breast cancer are reported together in 1 article.
Gene
TBK1
- HGNC
- HGNC:11584
9articles
9mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Comprehensive analysis of gene expression alterations in breast cancer patients via PKCθ-TBK1-mTORC1 signaling pathway.
PMID 41316051 | PMCID PMC12670725 | DOI 10.1186/s12885-025-15352-w · BMC cancer · 2025 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TBK1 | “The current study was designed to investigate the relative expression levels of PRKCQ and its downstream components, including TANK-binding kinase 1 (TBK1), mammalian target of rapamycin (mTORC1), ribosomal S6 kinase (S6K), Jun Proto-Oncogene (JUNB), and the tumor suppressor gene p21, in breast cancer.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Comprehensive analysis of gene expression alterations in breast cancer patients via PKCθ-TBK1-mTORC1 signaling pathway.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | PRKCQ | “Protein kinase C theta (PRKCQ/PKCθ), a serine/threonine kinase, has been implicated in immune signaling and cancer.” | 0.98 | hgnc_dict_v1 |
| gene | JUNB | “The current study was designed to investigate the relative expression levels of PRKCQ and its downstream components, including TANK-binding kinase 1 (TBK1), mammalian target of rapamycin (mTORC1), ribosomal S6 kinase (S6K), Jun Proto-Oncogene (JUNB), and the tumor suppressor gene p21, in breast cancer.” | 0.98 | hgnc_dict_v1 |