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TERT and diabetes mellitus are reported together in 2 articles.
Gene
TERT
- HGNC
- HGNC:11730
48articles
48mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
thyroid cancer 25breast cancer 2colorectal cancer 2diabetes mellitus 2endometrial cancer 2leukemia 2prostate cancer 2hypertension 1
Reported variants (articles · ClinVar status)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Identification of polymorphic alleles in TERC and TERT gene reprogramming the telomeres of newborn and legacy with parental health.
PMID 38192544 | PMCID PMC10772381 | DOI 10.1016/j.sjbs.2023.103897 · Saudi journal of biological sciences · 2024 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TERT | “Identification of polymorphic alleles in TERC and TERT gene reprogramming the telomeres of newborn and legacy with parental health.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “This study explored the polymorphic alleles of TERC and TERT gene in parents-newborn (triad) and its association with telomere length (TL) and parental diseases (mother: Gestational Diabetes Mellitus (GDM), Preeclampsia, fathers: Diabetes, Hypertension).” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | TERC | “Identification of polymorphic alleles in TERC and TERT gene reprogramming the telomeres of newborn and legacy with parental health.” | 0.98 | hgnc_dict_v1 |
| phenotype | hypertension | “This study explored the polymorphic alleles of TERC and TERT gene in parents-newborn (triad) and its association with telomere length (TL) and parental diseases (mother: Gestational Diabetes Mellitus (GDM), Preeclampsia, fathers: Diabetes, Hypertension).” | 0.98 | phenotype_alias_lexicon_v2 |
Unravelling the role of telomere shortening with ageing and their potential association with diabetes, cancer, and related lifestyle factors.
PMID 36137363 | DOI 10.1016/j.tice.2022.101925 · Tissue & cell · 2022 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TERT | “Upregulated Telomerase activity and reactivation of telomeres is observed in > 70 % of cancer patients by TERT point mutations, rearrangements, DNA amplifications, and transcript fusions, making it a useful marker in diagnosis and prognosis of various cancers.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Unravelling the role of telomere shortening with ageing and their potential association with diabetes, cancer, and related lifestyle factors.” | 0.93 | phenotype_alias_lexicon_v2 |
| phenotype | obesity | “Telomere length alteration is often linked with lifestyle factors such as age, obesity, exposure to pesticides and pollution, depression, unhealthy diet, lack of exercise, and stress.” | 0.98 | phenotype_alias_lexicon_v2 |