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TMPRSS2 and asthma are reported together in 1 article.
Gene
TMPRSS2
- HGNC
- HGNC:11876
22articles
22mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Asthma
285articles
285mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Asthma Associated Cytokines Regulate the Expression of SARS-CoV-2 Receptor ACE2 in the Lung Tissue of Asthmatic Patients.
PMID 35111161 | PMCID PMC8801531 | DOI 10.3389/fimmu.2021.796094 · Frontiers in immunology · 2021 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TMPRSS2 | “One of the risk factors for acquiring COVID-19 is the level of expression of SARS-CoV-2 entry receptors, ACE2 and TMPRSS2, in lung tissue.” | 0.98 | hgnc_dict_v1 |
| phenotype | asthma | “Asthma Associated Cytokines Regulate the Expression of SARS-CoV-2 Receptor ACE2 in the Lung Tissue of Asthmatic Patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | ACE2 | “Asthma Associated Cytokines Regulate the Expression of SARS-CoV-2 Receptor ACE2 in the Lung Tissue of Asthmatic Patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | COVID-19 | “It is still controversial whether chronic lung inflammation increases the risk for COVID-19.” | 0.98 | phenotype_alias_lexicon_v2 |