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TMPRSS2 and prostate cancer are reported together in 1 article.
Gene
TMPRSS2
- HGNC
- HGNC:11876
22articles
22mentions
2variants with confirmed gene link
Most co-reported phenotypes (articles)
Reported variants (articles · ClinVar status)
Phenotype
Prostate cancer
218articles
218mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Identifying drug targets and evaluating KLK3-targeted inhibitors for prostate cancer using in-silico and in-vitro approaches.
PMID 40932598 | DOI 10.1007/s12032-025-02896-x · Medical oncology (Northwood, London, England) · 2025 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TMPRSS2 | “Text mining of 237,357 PubMed articles identified KLK3 as the most frequently cited protein (10,477 mentions in titles; 162,619 in abstracts), with strong co-mentions of AR, TMPRSS2, and ERG (χ2, *p* < 0.001).” | 0.98 | hgnc_dict_v1 |
| phenotype | prostate cancer | “Identifying drug targets and evaluating KLK3-targeted inhibitors for prostate cancer using in-silico and in-vitro approaches.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | KLK3 | “Prostate cancer remains a significant oncological challenge, driven by molecular factors such as KLK3 (kallikrein-related peptidase 3).” | 0.98 | hgnc_dict_v1 |