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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
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TTN and breast cancer are reported together in 1 article.
Gene
TTN
- HGNC
- HGNC:12403
11articles
11mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Breast cancer
1,211articles
1,211mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Personalized mRNA vaccine for breast cancer: in silico neoantigen discovery and immunogenic validation in a Pakistani patient cohort.
PMID 42064455 | PMCID PMC13125589 | DOI 10.1007/s40203-026-00631-6 · In silico pharmacology · 2026 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TTN | “Somatic variant analysis indicated a high mutational burden, including 6005 missense mutations in genes such as MUC3A and TTN.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Personalized mRNA vaccine for breast cancer: in silico neoantigen discovery and immunogenic validation in a Pakistani patient cohort.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | MUC3A | “Somatic variant analysis indicated a high mutational burden, including 6005 missense mutations in genes such as MUC3A and TTN.” | 0.98 | hgnc_dict_v1 |
| gene | TLR9 | “Across 500 ns molecular dynamics simulations, the vaccine construct remained conformationally stable and showed favorable predicted interactions with innate immune receptors, with strong binding free energies for TLR9 (ΔG = - 148.8 kcal/mol) and TLR2 (ΔG = - 16.7 kcal/mol).” | 0.98 | hgnc_dict_v1 |