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TYK2 and diabetes mellitus are reported together in 1 article.
Gene
TYK2
- HGNC
- HGNC:12440
15articles
15mentions
1variants with confirmed gene link
Most co-reported phenotypes (articles)
atopic dermatitis 2inflammatory bowel disease 2rheumatoid arthritis 2COVID-19 1Crohn disease 1diabetes mellitus 1tuberculosis 1ulcerative colitis 1
Reported variants (articles · ClinVar status)
Phenotype
Diabetes mellitus
2,156articles
2,156mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Genome-Wide Identification of lncRNA and mRNA for Diagnosing Type 2 Diabetes in Saudi Arabia.
PMID 37731406 | PMCID PMC10508282 | DOI 10.2147/PGPM.S427977 · Pharmacogenomics and personalized medicine · 2023 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TYK2 | “This study identified three lncRNA target genes (KLF2, CREBBP, and REL) and seven mRNAs (PIK3CD, PIK3R5, IL6R, TYK2, ZAP70, LAMTOR4, and SSH2) significantly enriched in important pathways, playing a role in the progression of T2DM.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Genome-Wide Identification of lncRNA and mRNA for Diagnosing Type 2 Diabetes in Saudi Arabia.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | KLF2 | “This study identified three lncRNA target genes (KLF2, CREBBP, and REL) and seven mRNAs (PIK3CD, PIK3R5, IL6R, TYK2, ZAP70, LAMTOR4, and SSH2) significantly enriched in important pathways, playing a role in the progression of T2DM.” | 0.98 | hgnc_dict_v1 |
| gene | CREBBP | “This study identified three lncRNA target genes (KLF2, CREBBP, and REL) and seven mRNAs (PIK3CD, PIK3R5, IL6R, TYK2, ZAP70, LAMTOR4, and SSH2) significantly enriched in important pathways, playing a role in the progression of T2DM.” | 0.98 | hgnc_dict_v1 |