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ULK1 and intellectual disability are reported together in 2 articles.
Gene
ULK1
- HGNC
- HGNC:12558
9articles
9mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Intellectual disability
- HPO
- HP:0001249
736articles
736mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Resveratrol alleviates neurological disorders and motor dysfunction in 3-NP induced- Huntington's Disease in rats: Role of activating AMPK/SIRT1/ULK1 autophagy pathway.
PMID 42331250 | DOI 10.1016/j.neuropharm.2026.111084 · Neuropharmacology · 2026 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ULK1 | “Resveratrol alleviates neurological disorders and motor dysfunction in 3-NP induced- Huntington's Disease in rats: Role of activating AMPK/SIRT1/ULK1 autophagy pathway.” | 0.98 | hgnc_dict_v1 |
| phenotype | intellectual disability | “Huntington's disease (HD) is a genetic neurodegenerative disease characterized by striatum damage, which results in a number of uncontrollable muscle movements alongside intellectual and cognitive impairment.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | SIRT1 | “Resveratrol alleviates neurological disorders and motor dysfunction in 3-NP induced- Huntington's Disease in rats: Role of activating AMPK/SIRT1/ULK1 autophagy pathway.” | 0.98 | hgnc_dict_v1 |
| phenotype | Parkinson disease | “RESV showed promising neuroprotective effects against Alzheimer's and Parkinson's disease.” | 0.93 | phenotype_alias_lexicon_v2 |
Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects.
PMID 21457577 | PMCID PMC3083380 | DOI 10.1186/1755-8166-4-9 · Molecular cytogenetics · 2011 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | ULK1 | “Among the 52 deleted genes, P2RX2, ULK1, FZD10, RAN, NCOR2 STX2, TESC, FBXW8, and TBX3 are noteworthy since they may have a role in observed phenotype.” | 0.98 | hgnc_dict_v1 |
| phenotype | intellectual disability | “RESULTS: We have clinically screened more than 100 patients with dysmorphic features, mental retardation and normal karyotype using high density oligo array-CGH (aCGH) and identified a ~9.2 Mb hemizygous interstitial deletion at the 12q telomere (Chromosome 12: 46,XY,del(12)(q24.31q24.33) in a severely developmentally retarded patient having dysmorphic features such as low set ears, microcephaly, undescended testicles, bent elbow, kyphoscoliosis, and micropenis.” | 0.93 | phenotype_alias_lexicon_v2 |
| gene | P2RX2 | “Among the 52 deleted genes, P2RX2, ULK1, FZD10, RAN, NCOR2 STX2, TESC, FBXW8, and TBX3 are noteworthy since they may have a role in observed phenotype.” | 0.98 | hgnc_dict_v1 |
| gene | FZD10 | “Among the 52 deleted genes, P2RX2, ULK1, FZD10, RAN, NCOR2 STX2, TESC, FBXW8, and TBX3 are noteworthy since they may have a role in observed phenotype.” | 0.98 | hgnc_dict_v1 |