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XIAP and inflammatory bowel disease are reported together in 1 article.
Gene
XIAP
- HGNC
- HGNC:592
34articles
34mentions
0variants with confirmed gene link
Most co-reported phenotypes (articles)
Phenotype
Inflammatory bowel disease
693articles
693mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.
PMID 24942515 | DOI 10.1016/j.jaci.2014.04.031 · The Journal of allergy and clinical immunology · 2014 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | XIAP | “X-linked inhibitor of apoptosis (XIAP) deficiency causes X-linked lymphoproliferative syndrome type 2.” | 0.98 | hgnc_dict_v1 |
| phenotype | inflammatory bowel disease | “BACKGROUND: Crohn disease is an inflammatory bowel disease (IBD) with a complex mode of inheritance.” | 0.98 | phenotype_alias_lexicon_v2 |
| gene | NOD2 | “Although nucleotide binding and oligomerization domain containing 2 (NOD2) is the strongest risk factor, the cause of Crohn disease remains unknown in the majority of the cases.” | 0.98 | hgnc_dict_v1 |
| gene | NOD1 | “Nucleotide binding and oligomerization domain containing 1 (NOD1)-mediated IL-6 and IL-8 production was defective in fibroblasts from XIAP-deficient patients.” | 0.98 | hgnc_dict_v1 |