MERS
SaudiVarKB evidence summary derived from retained literature mentions.
119Phenotype mentions
100Publications
50Associated gene records
41Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| DPP4 | HGNC:3009 | 8 | 8 |
| ACE2 | HGNC:13557 | 6 | 6 |
| CCL5 | HGNC:10632 | 1 | 1 |
| CD4 | HGNC:1678 | 1 | 1 |
| TNF | HGNC:11892 | 1 | 1 |
| PPARG | HGNC:9236 | 1 | 1 |
| STAT1 | HGNC:11362 | 1 | 1 |
| BCR | HGNC:1014 | 1 | 1 |
| IFIH1 | HGNC:18873 | 1 | 1 |
| ISG15 | HGNC:4053 | 1 | 1 |
| EGR1 | HGNC:3238 | 1 | 1 |
| ACE | HGNC:2707 | 1 | 1 |
| STAT2 | HGNC:11363 | 1 | 1 |
| C5 | HGNC:1331 | 1 | 1 |
| TLR4 | HGNC:11850 | 1 | 1 |
| HLA-A | HGNC:4931 | 1 | 1 |
| HLA-DQB1 | HGNC:4944 | 1 | 1 |
| CD44 | HGNC:1681 | 1 | 1 |
| CXCL10 | HGNC:10637 | 1 | 1 |
| IFNL1 | HGNC:18363 | 1 | 1 |
| MYC | HGNC:7553 | 1 | 1 |
| CCL2 | HGNC:10618 | 1 | 1 |
| CXCL1 | HGNC:4602 | 1 | 1 |
| MX1 | HGNC:7532 | 1 | 1 |
| OASL | HGNC:8090 | 1 | 1 |
| BIRC3 | HGNC:591 | 1 | 1 |
| MTHFD2 | HGNC:7434 | 1 | 1 |
| TLR2 | HGNC:11848 | 1 | 1 |
| FOXO3 | HGNC:3821 | 1 | 1 |
| CD14 | HGNC:1628 | 1 | 1 |
| PMAIP1 | HGNC:9108 | 1 | 1 |
| CD163 | HGNC:1631 | 1 | 1 |
| NFKBIA | HGNC:7797 | 1 | 1 |
| IFIT1 | HGNC:5407 | 1 | 1 |
| CD9 | HGNC:1709 | 1 | 1 |
| EIF2AK2 | HGNC:9437 | 1 | 1 |
| OAS1 | HGNC:8086 | 1 | 1 |
| IRF9 | HGNC:6131 | 1 | 1 |
| ICAM1 | HGNC:5344 | 1 | 1 |
| AREG | HGNC:651 | 1 | 1 |
| SGK1 | HGNC:10810 | 1 | 1 |
| BBC3 | HGNC:17868 | 1 | 1 |
| DDIT3 | HGNC:2726 | 1 | 1 |
| SESN2 | HGNC:20746 | 1 | 1 |
| GADD45A | HGNC:4095 | 1 | 1 |
| RELB | HGNC:9956 | 1 | 1 |
| SMARCD3 | HGNC:11108 | 1 | 1 |
| PARL | HGNC:18253 | 1 | 1 |
| GLIPR1 | HGNC:17001 | 1 | 1 |
| GP1BA | HGNC:4439 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| T746K | T746K | 2 | 2 |
| M252Y | M252Y | 1 | 1 |
| S254T | S254T | 1 | 1 |
| T256E | T256E | 1 | 1 |
| H433K | H433K | 1 | 1 |
| N434F | N434F | 1 | 1 |
| I529T | I529T | 1 | 1 |
| E536K | E536K | 1 | 1 |
| L745F | L745F | 1 | 1 |
| L411F | L411F | 1 | 1 |
| T424I | T424I | 1 | 1 |
| L506F | L506F | 1 | 1 |
| N501Y | N501Y | 1 | 1 |
| D614G | D614G | 1 | 1 |
| K986P | K986P | 1 | 1 |
| V987P | V987P | 1 | 1 |
| Q1020R | Q1020R | 1 | 1 |
| R162H | R162H | 1 | 1 |
| T21I | T21I | 1 | 1 |
| M49L | M49L | 1 | 1 |
| S144A | S144A | 1 | 1 |
| E166A | E166A | 1 | 1 |
| L167F | L167F | 1 | 1 |
| rs35128070 | rs35128070 | 1 | 1 |
| rs1861978 | rs1861978 | 1 | 1 |
| rs79700168 | rs79700168 | 1 | 1 |
| rs17574 | rs17574 | 1 | 1 |
| L18F | L18F | 1 | 1 |
| Y145H | Y145H | 1 | 1 |
| M153T | M153T | 1 | 1 |
| F157S | F157S | 1 | 1 |
| G476S | G476S | 1 | 1 |
| L611F | L611F | 1 | 1 |
| A879S | A879S | 1 | 1 |
| C1247F | C1247F | 1 | 1 |
| C1254F | C1254F | 1 | 1 |
| H49Y | H49Y | 1 | 1 |
| S50L | S50L | 1 | 1 |
| A845V | A845V | 1 | 1 |
| P1143L | P1143L | 1 | 1 |
| R911C | R911C | 1 | 1 |
Associated population records
Co-mentioned in the same publications| Population | Identifier / context | Articles | Mentions |
|---|---|---|---|
| Saudi Arabia | — | 32 | 32 |
| Population record | Cohort 19 | 6 | 6 |
| Saudi Arabia · Jeddah | — | 4 | 4 |
| Saudi Arabia | Cohort 64 | 1 | 1 |
| Saudi Arabia · Riyadh | — | 1 | 1 |
| Population record | Cohort 2 | 1 | 1 |
| Saudi Arabia | Cohort 27 | 1 | 1 |
| Riyadh | — | 1 | 1 |
| Population record | Cohort 504 | 1 | 1 |
| Saudi Arabia | Cohort 32 | 1 | 1 |
| Population record | Cohort 150 | 1 | 1 |
| Saudi Arabia | Cohort 44 | 1 | 1 |
| Saudi Arabia | Cohort 6 | 1 | 1 |
| Saudi Arabia | Cohort 2,020 | 1 | 1 |
| Riyadh | Cohort 19 | 1 | 1 |
| Saudi Arabia | Cohort 2,591 | 1 | 1 |
| Saudi Arabia | Cohort 2,379 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 2,562 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 28 | 1 | 1 |
| Population record | Cohort 8,000 | 1 | 1 |
| Saudi Arabia | Cohort 180 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 143 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 116 | 1 | 1 |
| Population record | Cohort 2,494 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 381 | 1 | 1 |
| Saudi Arabia · Makkah | Cohort 417 | 1 | 1 |
Supporting publications
100 records- 2026Intranasal CD40-targeted recombinant MERS-CoV S1 protein is superior to intramuscular immunization in eliciting systemic and mucosal immune responses in mice.Vaccine1 mentions
- 2026A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses.Nature communications1 mentions
- 2026Structural resilience of conserved-site mutations in the MERS-CoV membrane protein: insights into stability and conformational dynamics.Journal of biomolecular structure & dynamics1 mentions
- 2026Heterologous saRNA prime - multivalent protein boost strategy induces broad and durable immunity against SARS-CoV-2 and MERS-CoV.Scientific reports1 mentions
- 2026Characterisation of Naturally Occurring MERS-CoV Spike Mutations and Their Impact on Fusion and Neutralisation.Viruses1 mentions
- 2026Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4.Journal of virology1 mentions
- 2026Broadly Protective Antibody-Like Vaccines Against Highly Pathogenic Coronaviruses.Journal of medical virology1 mentions
- 2026Delving into the innate and adaptive immunity of camelids: a paradigm of interspecies adaptation and evolutionary innovation.Frontiers in immunology1 mentions
- 2025Ongoing Evolution of Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2023-2024.Emerging infectious diseases1 mentions
- 2025A 10 Year Long-Lived Cellular and Humoral MERS-CoV Immunity Cross-Recognizing the Wild-Type and Variants of SARS-CoV-2: A Potential One-Way MERS-CoV Cross-Protection Toward a Pan-Coronavirus Vaccine.Journal of medical virology1 mentions
- 2025Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses.Cell1 mentions
- 2025Modulatory Effects of the Recombinant Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike S1 Subunit Protein on the Phenotype of Camel Monocyte-Derived Macrophages.Biology1 mentions
- 2025Characteristic profiling of CHO-cell expressed MERS-CoV RBD-Fc.International journal of biological macromolecules1 mentions
- 2025Intrinsic factors behind long COVID: exploring the role of nucleocapsid protein in thrombosis.PeerJ1 mentions
- 2025Analysis of the metagenomic assembled genome of MERS-CoV and Alpha-CoV from Camelus dromedarius in Saudi Arabia.Journal of infection and public health1 mentions
- 2025The Differences in the Evolutionary Dynamics of MERS and SARS Coronaviruses.Viruses1 mentions
- 2025Respiratory and gastrointestinal infections among Hajj pilgrims during the 2012-2025 seasons: A systematic review.Journal of infection and public health1 mentions
- 2025Thrombotic complications in critically ill patients with coronavirus infections: A comparative study of MERS and COVID-19.Medicine1 mentions
- 2025MERS-CoV RBD-mRNA Presents Better Immunogenicity and Protection than the Spike-mRNA.Cells1 mentions
- 2025MERS-COV in the Middle East, a one health concept approach.One health (Amsterdam, Netherlands)1 mentions
- 2024Enumeration of olive derived lignan, pinoresinol for activity against recent Omicron variant spike protein for structure-based drug design, DFT, molecular dynamics simulations, and MMGBSA studies.Journal of applied genetics1 mentions
- 2024Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations.Medical science monitor : international medical journal of experimental and clinical research1 mentions
- 2024ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: a quick therapeutic option for current and future coronaviruses outbreaks.Antibody therapeutics1 mentions
- 2024Utilizing sinapic acid as an inhibitory antiviral agent against MERS-CoV PLpro.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2024Genomic Diversity and Recombination Analysis of the Spike Protein Gene from Selected Human Coronaviruses.Biology1 mentions
- 2024Study of key residues in MERS-CoV and SARS-CoV-2 main proteases for resistance against clinically applied inhibitors nirmatrelvir and ensitrelvir.Npj viruses1 mentions
- 2024Circulation of Non-Middle East Respiratory Syndrome (MERS) Coronaviruses in Imported Camels in Saudi Arabia.Cureus1 mentions
- 2024Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions.European journal of medicinal chemistry1 mentions
- 2024Middle East Respiratory Syndrome Coronavirus Could be a Priority Pathogen to Cause Public Health Emergency: Noticeable Features and Counteractive Measures.Environmental health insights1 mentions
- 2024Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses.bioRxiv : the preprint server for biology1 mentions
- 2024Elucidating the role of PPARG inhibition in enhancing MERS virus immune response: A network pharmacology and computational drug discovery.Journal of infection and public health1 mentions
- 2024Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells.Journal of virology1 mentions
- 2024Identifying COVID-19 variant through symptoms profile: Would it be possible? A rapid review.BMC infectious diseases1 mentions
- 2024Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution.Current protocols1 mentions
- 2023Convalescent Plasma Therapy against COVID-19: An Update on the Changing Facets of the ongoing Pandemic.Current pharmaceutical biotechnology1 mentions
- 2023Middle East respiratory syndrome coronavirus-a 10-year (2012-2022) global analysis of human and camel infections, genomic sequences, lineages, and geographical origins.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases1 mentions
- 2023MICaFVi: A Novel Magnetic Immuno-Capture Flow Virometry Nano-Based Diagnostic Tool for Detection of Coronaviruses.Biosensors1 mentions
- 2023Molecular Characterization of Influenza A/H3N2 Virus Isolated from Indonesian Hajj and Umrah Pilgrims 2013 to 2014.Life (Basel, Switzerland)1 mentions
- 2023Coronavirus and co-infections: A Saudi Arabian perspective.Saudi journal of biological sciences1 mentions
- 2023An updated review on pathogenic coronaviruses (CoVs) amid the emergence of SARS-CoV-2 variants: A look into the repercussions and possible solutions.Journal of infection and public health1 mentions
- 2023A Modified Recombinant DNA-Based SARS-CoV-2 Vaccine Expressing Stabilized Uncleavable Spike Protein Elicits Humoral and Cellular Immunity against Various SARS-CoV-2 Variants of Concern.Transboundary and emerging diseases1 mentions
- 2022Exploring structural dynamics of the MERS-CoV receptor DPP4 and mutant DPP4 receptors.Journal of biomolecular structure & dynamics1 mentions
- 2022Role of Potential COVID-19 Immune System Associated Genes and the Potential Pathways Linkage with Type-2 Diabetes.Combinatorial chemistry & high throughput screening1 mentions
- 2022Association of HLA class I and II genes with Middle East respiratory syndrome coronavirus infection in Koreans.Immunity, inflammation and disease1 mentions
- 2022Emergence, evolution, and vaccine production approaches of SARS-CoV-2 virus: Benefits of getting vaccinated and common questions.Saudi journal of biological sciences1 mentions
- 2022Literature Review of Omicron: A Grim Reality Amidst COVID-19.Microorganisms1 mentions
- 2022Low levels of soluble DPP4 among Saudis may have constituted a risk factor for MERS endemicity.PloS one1 mentions
- 2022Lessons from SARS-CoV, MERS-CoV, and SARS-CoV-2 Infections: What We Know So Far.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale1 mentions
- 2022RT-PCR Ct values combined with age predicts invasive mechanical ventilation and mortality in hospitalized COVID-19 patients in a MERS-CoV-endemic country.Heliyon1 mentions
- 2022Multi-Stage Temporal Convolution Network for COVID-19 Variant Classification.Diagnostics (Basel, Switzerland)1 mentions
- 2021Comparative analysis of the genome structure and organization of the Middle East respiratory syndrome coronavirus (MERS-CoV) 2012 to 2019 revealing evidence for virus strain barcoding, zoonotic transmission, and selection pressure.Reviews in medical virology1 mentions
- 2021The emerging SARS-CoV-2 papain-like protease: Its relationship with recent coronavirus epidemics.Journal of medical virology1 mentions
- 2021Inflammatory Response and Phenotyping in Severe Acute Respiratory Infection From the Middle East Respiratory Syndrome Coronavirus and Other Etiologies.Critical care medicine1 mentions
- 2021Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and Other Coronaviruses: A Genome-wide Comparative Annotation and Analysis.Molecular and cellular biochemistry1 mentions
- 2021SARS-CoV-2: An Update on Genomics, Risk Assessment, Potential Therapeutics and Vaccine Development.International journal of environmental research and public health1 mentions
- 2021Surface-aerosol stability and pathogenicity of diverse MERS-CoV strains from 2012 - 2018.bioRxiv : the preprint server for biology1 mentions
- 2021The Recombination Potential between SARS-CoV-2 and MERS-CoV from Cross-Species Spill-over Infections.Journal of epidemiology and global health1 mentions
- 2021Limited Genetic Diversity Detected in Middle East Respiratory Syndrome-Related Coronavirus Variants Circulating in Dromedary Camels in Jordan.Viruses1 mentions
- 2021Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms.Viruses1 mentions
- 2021Sequence and phylogentic analysis of MERS-CoV in Saudi Arabia, 2012-2019.Virology journal1 mentions
- 2021Epidemiology and evolution of Middle East respiratory syndrome coronavirus, 2012-2020.Infectious diseases of poverty1 mentions
- 2021Profile of Circulatory Cytokines and Chemokines in Human Coronaviruses: A Systematic Review and Meta-Analysis.Frontiers in immunology1 mentions
- 2021Immunopathogenesis and immunobiology of SARS-CoV-2.Le infezioni in medicina1 mentions
- 2021A Reliable Indirect ELISA Protocol for Detection of Human Antibodies Directed to SARS-CoV-2 NP Protein.Diagnostics (Basel, Switzerland)1 mentions
- 2021Phenotypic and genetic characterization of MERS coronaviruses from Africa to understand their zoonotic potential.Proceedings of the National Academy of Sciences of the United States of America1 mentions
- 2021The lethal internal face of the coronaviruses: Kidney tropism of the SARS, MERS, and COVID19 viruses.IUBMB life1 mentions
- 2021Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS.mSphere1 mentions
- 2021Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach.Computers in biology and medicine1 mentions
- 2021An overview of SARS-COV-2 epidemiology, mutant variants, vaccines, and management strategies.Journal of infection and public health1 mentions
- 2021Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5.Nature communications1 mentions
- 2021Genetic Insights into the Middle East Respiratory Syndrome Coronavirus Infection among Saudi People.Vaccines1 mentions
- 2021Surface‒Aerosol Stability and Pathogenicity of Diverse Middle East Respiratory Syndrome Coronavirus Strains, 2012‒2018.Emerging infectious diseases1 mentions
- 2021Nanotechnology Applications of Flavonoids for Viral Diseases.Pharmaceutics1 mentions
- 2021Potential Drug Strategies to Target Coronaviruses.Advances in experimental medicine and biology1 mentions
- 2021Immunoinformatics-guided design of a multi-epitope vaccine based on the structural proteins of severe acute respiratory syndrome coronavirus 2.RSC advances1 mentions
- 2020The Phylogeography of MERS-CoV in Hospital Outbreak-Associated Cases Compared to Sporadic Cases in Saudi Arabia.Viruses1 mentions
- 2020Analysis of Codon Usage and Nucleotide Bias in Middle East Respiratory Syndrome Coronavirus Genes.Evolutionary bioinformatics online1 mentions
- 2020[Source of the COVID-19 pandemic: ecology and genetics of coronaviruses (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (subgenus Sarbecovirus), and MERS-CoV (subgenus Merbecovirus).].Voprosy virusologii1 mentions
- 2020Does coronavirus affect the audio-vestibular system? A rapid systematic review.International journal of audiology1 mentions
- 2020Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach.Biochimica et biophysica acta. Molecular basis of disease1 mentions
- 2020SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype.Gene1 mentions
- 2020Evolving sequence mutations in the Middle East Respiratory Syndrome Coronavirus (MERS-CoV).Journal of infection and public health1 mentions
- 2020Polyacylated anthocyanins constructively network with catalytic dyad residues of 3CLpro of 2019-nCoV than monomeric anthocyanins: A structural-relationship activity study with 10 anthocyanins using in-silico approaches.Journal of molecular graphics & modelling1 mentions
- 2020Review on the coronavirus disease (COVID-19) pandemic: Its outbreak and current status.International journal of clinical practice1 mentions
- 2020Why COVID-19 Transmission Is More Efficient and Aggressive Than Viral Transmission in Previous Coronavirus Epidemics?Biomolecules1 mentions
- 2020The Emergence of Human Pathogenic Coronaviruses: Lectins as Antivirals for SARS-CoV-2.Current pharmaceutical design1 mentions
- 2020COVID-19 in Human, Animal, and Environment: A Review.Frontiers in veterinary science1 mentions
- 2020COVID-19 Pandemic: Epidemiology, Etiology, Conventional and Non-Conventional Therapies.International journal of environmental research and public health1 mentions
- 2020Salient Conclusive Remarks on Epidemiology and Clinical Manifestations of Pediatric COVID-19: Narrative Review.Frontiers in pediatrics1 mentions
- 2020Novel SARS-CoV-2 outbreak and COVID19 disease; a systemic review on the global pandemic.Genes & diseases1 mentions
- 2020Zoonotic origins and animal hosts of coronaviruses causing human disease pandemics: A review.The Onderstepoort journal of veterinary research1 mentions
- 2019Middle East Respiratory Syndrome Coronavirus Infection Dynamics and Antibody Responses among Clinically Diverse Patients, Saudi Arabia.Emerging infectious diseases1 mentions
- 2019Middle East Respiratory Syndrome Coronavirus in Dromedaries in Ethiopia Is Antigenically Different From the Middle East Isolate EMC.Frontiers in microbiology1 mentions
- 2019Isolation and growth characterization of novel full length and deletion mutant human MERS-CoV strains from clinical specimens collected during 2015.The Journal of general virology1 mentions
- 2019Enzootic patterns of Middle East respiratory syndrome coronavirus in imported African and local Arabian dromedary camels: a prospective genomic study.The Lancet. Planetary health1 mentions
- 2018Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia.Journal of infection and public health1 mentions
- 2018Design and Delivery of Therapeutic siRNAs: Application to MERS-Coronavirus.Current pharmaceutical design1 mentions
- 2018The calm before the storm: clinical observations of Middle East respiratory syndrome (MERS) patients.Journal of chemotherapy (Florence, Italy)1 mentions
- 2018The prevalence of Middle East respiratory Syndrome coronavirus (MERS-CoV) infection in livestock and temporal relation to locations and seasons.Journal of infection and public health1 mentions
- 2018MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.Proceedings of the National Academy of Sciences of the United States of America1 mentions