Population record
Saudi Arabia · 20 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Saudi Arabia | “The participants were treated uniformly with tocilizumab on day 1, followed by cisplatin/docetaxel on day 2 every 4 weeks for a total of six cycles according to a traditional 3 + 3 design using a sentinel patient in each cohort. SCTR 19,111,002 (Saudi Food and Drug Authority) “Singlearm Phase I/II study of the safety, tolerability and efficacy of the Tocilizumab followed by cisplatin/docetaxel in patients with triple negative locally advanced breast cancer” (registration date 12/03/2020).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “There is a paucity of data on the clinical presentation of dystonia patients in Saudi Arabia and among Arabs. In this study we provide the largest description of dystonia patients in Saudi Arabia. In addition, we found 3 patients with homozygous GCH1 variants who displayed the classic phenotype of dopa-responsive dystonia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Genomic and Bioinformatics Analysis of Familial Partial Lipodystrophy Type 3 Identified in a Patient with Novel PPARγ Mutation and Robust Response to Pioglitazone. We identified a Saudi female with PFLD3 presented with partial lipoatrophy, uncontrolled diabetes, severe hypertriglyceridemia, and recurrent pancreatitis.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The Ministry of Health in Saudi Arabia reported an HIV incidence rate of 3 cases per 10,000 individuals. This study aimed to gain insight into the lived experience of Saudi patients living with HIV. CONCLUSION: Saudi patients diagnosed with HIV encounter numerous obstacles in their daily lives. By understanding the lived experience of HIV patients in Saudi Arabia, healthcare providers and policymakers can better support and enhance the quality of life for this population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Implementation of Next-Generation Sequencing in Saudi Arabia for HER2-Positive Breast Cancer. In 2021, around 2.3 million new cases are predicted to be discovered, with a mortality rate of 6.9% on average. We used TruSight Tumor 15 using Next-Generation Sequencing (NGS) to look at genetic changes in 126 Saudi women with stage I to IV breast cancer. c-MET (p = 0.001), c-KIT (p = 0.001), and PIK3CA (p = 0.0001), were shown to be substantially linked with HER2 positive patients. Our results recommend that patients with HER2 positive breast cancer in Saudi Arabia have a high mutational burden, which may be related to trastuzumab resistance.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Factors associated with age of diagnosis of autism spectrum disorder among children in Saudi Arabia: new insights from a cross-sectional study. The present exploratory study examined the influence of child and family characteristics on the age of ASD diagnosis in Saudi Arabia. Children who did not respond to their name were diagnosed 0.3 years earlier than other children (95% CI - 0.60, - 0.05), and engaging in challenging behavior was associated with a 0.5 year increase in age of diagnosis (95% CI 0.20, 0.81). Finally, those residing outside of Saudi Arabia were diagnosed with ASD 0.9 years earlier than those residing in Saudi Arabia (95% CI - 0.171, - 0.11).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “2020 Update to Spinal Muscular Atrophy Management in Saudi Arabia. We aimed to investigate physicians' opinions and perceptions toward management strategies of SMA across Saudi Arabia. This is a cross-sectional survey using a self-administered, structured questionnaire sent to physicians who care for SMA patients during the Saudi Pediatric Neurology Society annual conference. Though, 8.3% prescribed onasemnogene abeparvovec for 1-3 patients, while none of their patients started on the treatment. Pediatric neurologists are receptive to novel and innovative therapies for SMA in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Several case reports have been published of an association between RCVS and eclampsia, but to the best of our knowledge, only 3 cases were successfully treated with intravenous milrinone and this is the only patient reported in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Neuronal ceroid lipofuscinoses type 8: Expanding genotype/phenotype diversity-first report from Saudi Arabia. We report the cases of neuronal ceroid lipofuscinoses type 8 in 3 patients from 2 unrelated families, which was confirmed by molecular testing in 2 of them.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The purpose of this study was to assess retinal structure and function in 3 siblings presenting with late-stage RPE65 retinopathy and to assess the unmet need for such therapy in Saudi Arabia. METHODS: Search of the retinal dystrophy registry at King Khaled Eye Specialist Hospital and clinical examination including multimodal retinal imaging, full-field electroretinography (ERG), dark adapted full-field stimulus sensitivity thresholds, and molecular genetic testing in 3 patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Anonychia congenita in different generations of a single Saudi family. Here, we report 3 cases with anonychia congenita appearing in different generations of a single family in Kingdom of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Prevalence of Her3 in gastric cancer and its association with molecular prognostic markers: a Saudi cohort based study. In this study, we evaluated prevalence of Her3 in gastric cancer, in a Saudi cohort of cases, along with its association with prognostic markers p53 and Ki-67. Her 3 positive cases were also evaluated for Her-2neu co-expression.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The Eastern Mediterranean regional office (EMRO) of the world health organization (WHO) seems to have one of the highest prevalence rates worldwide, with at least 21.3 million HCV-infected patients. In Saudi Arabia and Egypt, genotype 4 was the most prevalent genotype with a rate of 65% (95% CI, 59 - 72) and 69% (95% CI, 36 - 100) respectively.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “In the present study, we reported 3 male cases from a Saudi family who presented with penile enlargement, progressive darkness of skin, hypertension, and cardiomyopathy.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Panton-Valentine leukocidin Staphylococcus aureus osteomyelitis of the femur in a Saudi child. We reported previously 3 children who had osteomyelitis caused by methicillin resistant Staphylococcus aureus. We report and discuss a case of Methicillin sensitive staphylococcus aureus encoding the PVL genes isolated from a child with acute osteomyelitis from Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Variable disease severity in Saudi Arabian and Sudanese families with c.3924 + 2 T > C mutation of LAMA2. We investigated clinical findings and performed molecular genetic analysis in 3 families from Saudi Arabia and 1 from Sudan in whom congenital muscular dystrophy 1A was suspected based on homozygosity mapping and laminin α2 chain deficiency. METHODS: We investigated 9 affected individuals from 1 Sudanese and 3 Saudi families in whom MDC1A was suggested by clinical, neuroimaging and/or pathological findings and by homozygosity mapping at the LAMA2 locus. Morphological and immunohistochemical analysis were performed in 3 patients from the 3 Saudi families.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Clinical course of 3 Saudi children with a severe phenotype.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Pattern of congenital brain malformations at a referral hospital in Saudi Arabia: an MRI study. PATIENTS AND METHODS: The records of all MRI brain examinations at our hospital over a period of 3 years for children younger than 15 years of age were reviewed.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Four patients from 3 Saudi Arabian families had delayed onset of immune deficiency due to homozygosity for a novel intronic mutation, g.31701T>A, in the last splice acceptor site of the adenosine deaminase (ADA) gene.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Schmidt's syndrome in a Saudi family. We present 3 patients from a Saudi family who are presented with polyglandular autoimmune syndrome type 2. Although this syndrome is rare, the incidence among Saudi Arabia or the Arab population is not known.” | 0.95 | saudi_context_rules_v1 |