Jeddah
Saudi Arabia · 12 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Saudi Arabia, Jeddah | “In Saudi Arabia, where consanguinity rates are high and primary immunodeficiency disorders are more prevalent, concerns have been raised regarding the safety of routine neonatal BCG vaccination. METHODS: This retrospective case series was conducted at a tertiary referral center in Jeddah, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “Familial Screening for the Prevention of Rare Diseases: A Focus on Lipodystrophy in Southern Saudi Arabia. This study aimed to identify the genetic variations associated with lipodystrophy in the southern part of Saudi Arabia. These patients were recruited from the Endocrinology and Diabetes Clinic at Jazan General Hospital and East Jeddah Hospital, both in the Kingdom of Saudi Arabia. Of the six families, four were consanguineously married from the same tribe, while the remaining belonged to the same clan.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “Consanguineous marriages, premarital screening, and genetic testing: a survey among Saudi university students. BACKGROUND: Marriage among cousins or close relatives, i.e., consanguinity, is prevalent in many parts of the world, especially the Muslim world. Across civilizations, cultural norms, religious beliefs, and economic factors affect consanguineous marriages (CMs); however, such marriages have social, genetic, and health repercussions. The present study investigated the university students' attitudes regarding CMs and factors influencing their attitudes at King Abdulaziz University (KAU), Jeddah, Kingdom of Saudi Arabia (KSA). METHODS: This cross-sectional prospective study was conducted at KAU Jeddah in 2023. CONCLUSION: The practice of CMs is still prevalent in Saudi culture, with almost half of the participants having CM parents and the majority reporting these marriages in their families.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “BACKGROUND: The Saudi population is characterized by a high fertility rate, a conservative sociocultural context, and an ongoing societal and lifestyle transition. METHODS: A one-year cross-sectional study involved 150 consecutive pregnant women aged between 18 and 47 years old, who presented for antenatal screening of CHD at the fetal echocardiography clinic for, of a teaching hospital in Jeddah, Saudi Arabia. RESULTS: Fetal echocardiography and CHD were correctly described by 60 % and 31.3 % of the participants respectively, while 40.7 % and 12 % recognized the association of congenital diseases with consanguinity and advanced maternal age respectively. On the other hand, childbearing intention was independently associated with the number of children (OR=0.34; p<0.001), consanguinity with husband (OR=3.64; p = 0.010), and history of gestational diabetes (OR=0.28; p = 0.040). CONCLUSION: Fertility expectations among Saudi mothers are more likely to be impacted by the personal experience and judgment of own pregnancy fitness, while no significant impact of fetal risks and events. This demonstrates a certain level of autonomy balanced with deeply rooted religious ethics yet combined with a lack of awareness about fetal and maternal risks associated with advanced maternal age and consanguinity.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “The participants were recruited from King Abdulaziz University Hospital (Jeddah, Saudi Arabia) and referred to King Fahad Centre for Medical Research (Jeddah, Saudi Arabia from April 2022 to June 2022. The consanguineous parents and one of the affected boys (aged 16 years old) underwent WES.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “Autosomal recessive cerebellar ataxia with spasticity due to a rare mutation in GBA2 gene in a large consanguineous Saudi family. In this study, we report the clinical features and genetic diagnosis of autosomal recessive cerebellar ataxia with spasticity due to a rare mutation in GBA2 gene in a large consanguineous Saudi family. We included a large consanguineous Saudi family with a presumptive clinical diagnosis of ataxia at King Abdulaziz Medical City in Jeddah, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “CASE REPORT: A 45-day-old boy presented to the outpatient clinic of dermatology at King Abdul Aziz Medical City, Jeddah, Saudi Arabia, with a flat scalp lesion on the space of the anterior fontanel. CONCLUSIONS: Aplasia cutis congenita is a rare condition of uncertain etiology, but consanguinity may play a role.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “Individualized medicine enabled by genomics in Saudi Arabia. The biomedical research sector in Saudi Arabia has recently received special attention from the government, which is currently supporting research aimed at improving the understanding and treatment of common diseases afflicting Saudi Arabian society. Among these, is the Centre of Excellence in Genomic Medicine Research (CEGMR) at King Abdulaziz University, Jeddah, with its internationally ranked and highly productive team performing translational research in the area of individualized medicine. Here, we present a panorama of the recent trends in different areas of biomedical research in Saudi Arabia drawing from our vision of where genomics will have maximal impact in the Kingdom of Saudi Arabia. We describe advances in a number of research areas including; congenital malformations, infertility, consanguinity and pre-implantation genetic diagnosis, cancer and genomic classifications in Saudi Arabia, epigenetic explanations of idiopathic disease, and pharmacogenomics and personalized medicine. We conclude that CEGMR will continue to play a pivotal role in advances in the field of genomics and research in this area is facing a number of challenges including generating high quality control data from Saudi population and policies for using these data need to comply with the international set up.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “Knowledge regarding the national premarital screening program among university students in western Saudi Arabia. OBJECTIVE: To explore the knowledge of university students in Jeddah, western Saudi Arabia, regarding the national premarital screening (PMS) program. METHODS: A self-administered questionnaire was distributed to a sample of 800 students at King Abdulaziz University (KAU), Jeddah, Kingdom of Saudi Arabia during the first semester of the academic year 2005--2006. RESULTS: Eighty-five percent of the students believed that gene mutations may lead to hereditary disorders, and 84% of the respondents believed that consanguinity can increase the risk for genetic diseases.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “A prospective study of congenital malformations among live born neonates at a University Hospital in Western Saudi Arabia. OBJECTIVE: To estimate the incidence of major and minor congenital malformations among liveborn infants at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. In 38.8% of cases parents were consanguineous. CONCLUSION: High incidence of major malformation in Jeddah.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “An epidemiological study of childhood disability in Jeddah, Saudi Arabia. Data were collected from the six governmental rehabilitation institutes and a sample of normal non-disabled school children in Jeddah City. Our results have shown that certain modifiable maternal risk factors affecting child health still exist in our community, such as early and late-age marriage and childbearing, as well as low education, unemployment, multiparity and consanguineous marriages.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Jeddah | “A non-comparative descriptive study of the risk factors for childhood disability, and the rehabilitation services in jeddah, saudi arabia. METHODS: Data were collected from six rehabilitation institutes for auditory, visual and mental disabilities in Jeddah City during April 1999. RESULTS: Certain modifiable risk factors affecting child health, such as early and late marriages and childbearing, illiteracy, unemployment, high parity and consanguineous marriages still exist in our community.” | 0.95 | saudi_context_rules_v1 |