renal failure
SaudiVarKB evidence summary derived from retained literature mentions.
482Phenotype mentions
100Publications
50Associated gene records
50Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| AGXT | HGNC:341 | 5 | 5 |
| ACE | HGNC:2707 | 4 | 4 |
| NPHS2 | HGNC:13394 | 4 | 4 |
| NLRP3 | HGNC:16400 | 3 | 3 |
| MYH9 | HGNC:7579 | 3 | 3 |
| COL4A5 | HGNC:2207 | 3 | 3 |
| PLCE1 | HGNC:17175 | 3 | 3 |
| NPHP1 | HGNC:7905 | 3 | 3 |
| TNF | HGNC:11892 | 2 | 2 |
| WT1 | HGNC:12796 | 2 | 2 |
| GLA | HGNC:4296 | 2 | 2 |
| CTNS | HGNC:2518 | 2 | 2 |
| G6PD | HGNC:4057 | 2 | 2 |
| MTHFR | HGNC:7436 | 2 | 2 |
| GRHPR | HGNC:4570 | 2 | 2 |
| HPSE2 | HGNC:18374 | 2 | 2 |
| FGF23 | HGNC:3680 | 2 | 2 |
| ALMS1 | HGNC:428 | 2 | 2 |
| CHRNA3 | HGNC:1957 | 2 | 2 |
| SLC4A1 | HGNC:11027 | 2 | 2 |
| APOL1 | HGNC:618 | 2 | 2 |
| COL4A3 | HGNC:2204 | 2 | 2 |
| COL4A4 | HGNC:2206 | 2 | 2 |
| KCNJ11 | HGNC:6257 | 2 | 2 |
| EGFR | HGNC:3236 | 2 | 2 |
| PKD1 | HGNC:9008 | 2 | 2 |
| PKD2 | HGNC:9009 | 2 | 2 |
| LCAT | HGNC:6522 | 2 | 2 |
| HLA-A | HGNC:4931 | 2 | 2 |
| LAMB2 | HGNC:6487 | 2 | 2 |
| SLC7A9 | HGNC:11067 | 2 | 2 |
| ATP6V1B1 | HGNC:853 | 2 | 2 |
| EPO | HGNC:3415 | 2 | 2 |
| UMOD | HGNC:12559 | 2 | 2 |
| PRKAR2B | HGNC:9392 | 2 | 2 |
| FRAS1 | HGNC:19185 | 2 | 2 |
| TFCP2L1 | HGNC:17925 | 2 | 2 |
| NPHS1 | HGNC:7908 | 2 | 2 |
| SHROOM3 | HGNC:30422 | 2 | 2 |
| CST3 | HGNC:2475 | 2 | 2 |
| RPLP0 | HGNC:10371 | 2 | 2 |
| SIRT1 | HGNC:14929 | 1 | 1 |
| RAN | HGNC:9846 | 1 | 1 |
| FOXP3 | HGNC:6106 | 1 | 1 |
| RET | HGNC:9967 | 1 | 1 |
| TSC2 | HGNC:12363 | 1 | 1 |
| IFT140 | HGNC:29077 | 1 | 1 |
| PKD1L1 | HGNC:18053 | 1 | 1 |
| ITSN1 | HGNC:6183 | 1 | 1 |
| NUP133 | HGNC:18016 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| p.Arg347His | p.Arg347His | 1 | 1 |
| p.Gln462Ter | p.Gln462Ter | 1 | 1 |
| p.Trp151Ter | p.Trp151Ter | 1 | 1 |
| c.33dup | c.33dup | 1 | 1 |
| p.Gly161Ser | p.Gly161Ser | 1 | 1 |
| p.Gly116Arg | p.Gly116Arg | 1 | 1 |
| p.Ala486Asp | p.Ala486Asp | 1 | 1 |
| C677T | C677T | 1 | 1 |
| c.1159A>C | c.1159A>C | 1 | 1 |
| c.907+2T>A | c.907+2T>A | 1 | 1 |
| c.1990G>A | c.1990G>A | 1 | 1 |
| p.Glu664Lys | p.Glu664Lys | 1 | 1 |
| c.1525-1G>A | c.1525-1G>A | 1 | 1 |
| R1680C | R1680C | 1 | 1 |
| c.2694-2_2694-1del | c.2694-2_2694-1del | 1 | 1 |
| rs628031 | rs628031 | 1 | 1 |
| rs145450955 | rs145450955 | 1 | 1 |
| rs3088442 | rs3088442 | 1 | 1 |
| rs2292334 | rs2292334 | 1 | 1 |
| IVS18 | IVS18 | 1 | 1 |
| p.Ala352Gly | p.Ala352Gly | 1 | 1 |
| rs3802230 | rs3802230 | 1 | 1 |
| rs4543 | rs4543 | 1 | 1 |
| rs4544 | rs4544 | 1 | 1 |
| rs1800871 | rs1800871 | 1 | 1 |
| rs833061 | rs833061 | 1 | 1 |
| rs3917887 | rs3917887 | 1 | 1 |
| c.241C>T | c.241C>T | 1 | 1 |
| p.Arg81Cys | p.Arg81Cys | 1 | 1 |
| rs12917707 | rs12917707 | 1 | 1 |
| p.R98W | p.R98W | 1 | 1 |
| p.K758M | p.K758M | 1 | 1 |
| M199R | M199R | 1 | 1 |
| R201H | R201H | 1 | 1 |
| R206H | R206H | 1 | 1 |
| Y330H | Y330H | 1 | 1 |
| rs4880 | rs4880 | 1 | 1 |
| rs769217 | rs769217 | 1 | 1 |
| 776C>G | 776C>G | 1 | 1 |
| p.Gln184Arg | p.Gln184Arg | 1 | 1 |
| rs3742330 | rs3742330 | 1 | 1 |
| c.2420delG | c.2420delG | 1 | 1 |
| c.1374_1378delTGTGC | c.1374_1378delTGTGC | 1 | 1 |
| rs3746444 | rs3746444 | 1 | 1 |
| c.949G>A | c.949G>A | 1 | 1 |
| p.Gly317Arg | p.Gly317Arg | 1 | 1 |
| c.11dupC | c.11dupC | 1 | 1 |
| rs699 | rs699 | 1 | 1 |
| rs4762 | rs4762 | 1 | 1 |
| rs14035 | rs14035 | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026The Influence of Renal Function on Safety and Effectiveness of Oral Anticoagulant Treatment among Frail Elderly Patients with Non-Valvular Atrial Fibrillation and Chronic Kidney Disease.Cardiology1 mentions
- 2026In Silico Characterization of Bromo-DragonFLY Binding to the 5-HT2A Receptor: Molecular Insights Into a Potent Designer Psychedelic.Proteins1 mentions
- 2026Protective role of scutellarin to counteract arsenic prompted renal damage in rats via the regulation of Nrf2/Keap1 pathway.International journal of environmental health research1 mentions
- 2026Association of poor vitamin K status with inflammation and gut microbiota in hemodialysis patients: A cross-sectional study.The Journal of nutritional biochemistry1 mentions
- 2026Genetic causes of nephrolithiasis and nephrocalcinosis in a pediatric population in Saudi Arabia.Pediatric nephrology (Berlin, Germany)1 mentions
- 2026Impact of Curcuma longa L. extract supplementation on the gut microbiota of hemodialysis patients.Jornal brasileiro de nefrologia1 mentions
- 2026GDF-15 as an integrative cardiometabolic biomarker.Clinica chimica acta; international journal of clinical chemistry1 mentions
- 2026Genotyping of Blastocystis species in hemodialysis patients from Makkah, Saudi Arabia.Parasites, hosts and diseases1 mentions
- 2026A Pathway to High Quality Clinical Trials in IgA Vasculitis Nephritis: Meeting Proceedings From a Multiprofessional International Collaborative Workshop.Kidney international reports1 mentions
- 2026Identification of monogenic variants in steroid-resistant and steroid-sensitive nephrotic syndrome.Pediatric nephrology (Berlin, Germany)1 mentions
- 2026β-Carboline alkaloid harmaline alleviates hyperuricemia-mediated renal inflammation by suppressing oxidative stress.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Prevalence of Carbapenem-Resistant Enterobacteriaceae in Intensive Care Units in Saudi Arabia: A 10-Year Systematic Review.Saudi medical journal1 mentions
- 2026National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal1 mentions
- 2026Nano-liposomal berberine and vildagliptin combination: A novel therapeutic approach against oxidative stress, inflammation, autophagy dysregulation, and fibrosis in diabetic nephropathy.Tissue & cell1 mentions
- 2026Diagnostic value of urinary protein to creatinine (UPC) ratio in dogs with chronic kidney disease (CKD): a systematic meta-analysis.Veterinary research communications1 mentions
- 2026The long-term impact of early HbA1c control on nephropathy, neuropathy, and retinopathy in type 2 diabetes: Findings from a large UK observational study.Journal of diabetes and its complications1 mentions
- 2026CMV retinitis: the diagnostic challenges and long-term outcomes. The experience of tertiary eye center in Saudi Arabia.Journal of ophthalmic inflammation and infection1 mentions
- 2026Complications in acute respiratory distress syndrome: a systematic review and meta-analysis.Critical care (London, England)1 mentions
- 2026Lived Experiences of Patients With Sickle Cell Disease and Kidney Failure: Insights From a Qualitative Study.Journal of patient experience1 mentions
- 2026Denys-Drash Syndrome by WT1 Gene: Clinical Variability and Management Challenges in Two Saudi Infants.Case reports in endocrinology1 mentions
- 2026Rapid Molecular Diagnostics for Bloodstream Infection in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland)1 mentions
- 2026Living Donor Liver Transplantation in Patients with or Without Acute-on-Chronic Liver Failure: A Single Center Experience.Journal of clinical medicine1 mentions
- 2026X-Linked immune dysregulation, polyendocrinopathy, and enteropathy (IPEX) syndrome with concurrent membranous and IgA nephropathy: a case report.BMC nephrology1 mentions
- 2026Impact of pre-operative factors on post-operative atrial fibrillation outcomes after cardiac surgery: systematic review with meta-analysis, trial sequential analysis, and meta-regression.Acta cardiologica1 mentions
- 2026Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction.European journal of pharmacology1 mentions
- 2026Autonomic-vascular dysregulation in CKD-associated hypertension: a narrative review with evidence hierarchy.Frontiers in neuroscience1 mentions
- 2026Hospital-Based Proportion of Diabetic Retinopathy and Associated Risk Factors Among Patients With Type 2 Diabetes Mellitus.Cureus1 mentions
- 2026An efficient LASSO framework for admixture-aware polygenic scores.HGG advances1 mentions
- 2026Oxidative Stress-Gut Microbiome Crosstalk: Intestinal Redox Imbalance and Probiotics Therapeutic Potential.Antioxidants (Basel, Switzerland)1 mentions
- 2026Intestinal microbiota profile and inflammation in patients undergoing hemodialysis: a comparison between the Southern and Southeastern regions of Brazil.Jornal brasileiro de nefrologia1 mentions
- 2026Utilization Patterns and Barriers to Sodium-Glucose Cotransporter-2 Inhibitor Prescription in Patients with Heart Failure: Real-World Evidence from Saudi Arabia.Cardiology and therapy1 mentions
- 2026Clinical practice recommendations for the diagnosis and management of nephropathic cystinosis.Nature reviews. Nephrology1 mentions
- 2026Timing and severity of acute kidney injury in hospitalized adults receiving vancomycin plus NKCC inhibitor with or without piperacillin-tazobactam.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Monogenic variants drive low recurrence risk in pediatric steroid-resistant nephrotic syndrome after kidney transplantation: a high-consanguinity cohort.Pediatric nephrology (Berlin, Germany)1 mentions
- 2026Systematic analysis of homozygous autosomal copy number losses in exomes improves diagnostic yield and uncovers ultra-rare recessive disorders.European journal of human genetics : EJHG1 mentions
- 2026Gut microbiota in a Saudi population with chronic kidney disease.World journal of nephrology1 mentions
- 2025Clinical Implications of Various Electroencephalographic Patterns in Post-Stroke Seizures. The Utility of Routine Electroencephalogram.Clinical EEG and neuroscience1 mentions
- 2025Trends and socioeconomic inequality of the burden of congenital abnormalities of the kidney and urinary tract among children and adolescents.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association1 mentions
- 2025Potential Trimethylamine (TMA)-Producing Bacteria in patients with chronic kidney disease undergoing hemodialysis.International urology and nephrology1 mentions
- 2025Genetic Contributions to Lower Urinary Tract Dysfunction.American journal of medical genetics. Part A1 mentions
- 2025A PDE1 inhibitor, vinpocetine, ameliorates epithelial-mesenchymal transition and renal fibrosis in adenine-induced chronic kidney injury in rats by targeting the DNMT1/Klotho/β-catenin/Snail 1 and MMP-7 pathways.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2025Is there a correlation between TMAO plasma levels and archaea in the gut of patients undergoing hemodialysis?International urology and nephrology1 mentions
- 2025Acute Kidney Injury after Hypoxic Ischemic Encephalopathy in Neonates Treated with Passive Versus Active Total Body Cooling.Therapeutic hypothermia and temperature management1 mentions
- 2025Diabetes Mellitus: Exploring Biomarkers, Complications, and Therapeutic Strategies with a Spotlight on Cyanobacterial Bioactive Compounds - A Comprehensive Review.Current diabetes reviews1 mentions
- 2025The impact of new-onset atrial fibrillation in the setting of acute coronary syndrome.Journal of cardiology1 mentions
- 2025Mitigation of gentamycin induced acute kidney injury due to benzothiazole derivatives N1 and N5: Antioxidant and renoprotective mechanisms in-vivo zebrafish.Toxicology letters1 mentions
- 2025Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah, Saudi Arabia.International journal of general medicine1 mentions
- 2025Prevalence and Factors Associated With Hepatitis C Virus in Riyadh, Saudi Arabia: A Large Cross-Sectional Study.Journal of epidemiology and global health1 mentions
- 2025A 65-Year-Old Man with Coronary Artery Embolism and Acute Inferior Myocardial Infarction Following Cardioversion for Ventricular Tachycardia.The American journal of case reports1 mentions
- 2025A Novel NPHP5 Gene Mutation in Three Siblings With Nephronophthisis Without Retinitis Pigmentosa: A Case Report.Case reports in genetics1 mentions
- 2025A cross-sectional study on gut microbiota and inflammation in patients with chronic kidney disease.The American journal of the medical sciences1 mentions
- 2025Gut microbiota and NLRP3 inflammasome activation in hemodialysis patients: exploring the link with systemic inflammation.Molecular biology reports1 mentions
- 2025Spexin peptide ameliorates renal injury in diabetic nephropathy rat model via modulation of metabolic, oxidative, inflammatory, and apoptotic dysregulations.Journal of physiology and biochemistry1 mentions
- 2025Mathematical analysis of modified blood glucose insulin model through fractal fractional operators.Scientific reports1 mentions
- 2025Tracing the molecular landscape of diabetic nephropathy: Insights from machine learning and experiment verification.Journal of diabetes investigation1 mentions
- 2025Uremic Pericarditis in a Patient With Hyperphosphatemic Familial Tumoral Calcinosis: Case Report.Case reports in medicine1 mentions
- 2025Fine-tuned deep transfer learning: an effective strategy for the accurate chronic kidney disease classification.PeerJ. Computer science1 mentions
- 2025Cloud-based real-time enhancement for disease prediction using Confluent Cloud, Apache Kafka, feature optimization, and explainable artificial intelligence.PeerJ. Computer science1 mentions
- 2025Hybrid Genome and Clinical Impact of Emerging Extensively Drug-Resistant Priority Bacterial Pathogen Acinetobacter baumannii in Saudi Arabia.Life (Basel, Switzerland)1 mentions
- 2025Patterns and Clinical Outcomes of Congenital Anomalies of the Kidney and Urinary Tract in Preterm Infants.Cureus1 mentions
- 2025An Efficient Lasso Framework for Admixture-Aware Polygenic Scores.bioRxiv : the preprint server for biology1 mentions
- 2025Benign acute childhood myositis: a retrospective cohort study from a large tertiary care children's hospital.Frontiers in pediatrics1 mentions
- 2025Advanced supervised machine learning methods for precise diabetes mellitus prediction using feature selection.Frontiers in medicine1 mentions
- 2025Remodeling of Gut Microbial Networks After Sulforaphane Supplementation in Patients with Chronic Kidney Disease.Life (Basel, Switzerland)1 mentions
- 2025Adult genomic medicine: lessons from a multisite study of 2700 patients.Genome medicine1 mentions
- 2025Epidemiological dynamics and rising trends of MRSA in Saudi Arabia: a 12-year observational study.Frontiers in cellular and infection microbiology1 mentions
- 2025Primary hyperoxaluria: insights into its clinical presentation, genetic mutations, and transplantation outcomes in a pediatric population in a tertiary care center.Orphanet journal of rare diseases1 mentions
- 2025Global, regional, and national burden of chronic kidney disease in adults, 1990-2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions
- 2025Recurrent Stroke and Progression of Left Ventricular Thrombus During Apixaban Therapy in a Patient with Severe Ischemic Cardiomyopathy: A Case Report.The American journal of case reports1 mentions
- 2025Audiological Findings in Hemodialysis Patients.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
- 2025Dysregulation of Niacin-Derived NAD+ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes.Medicina (Kaunas, Lithuania)1 mentions
- 2024Current and Novel Biomarkers of Progression Risk in Children with Chronic Kidney Disease.Nephron1 mentions
- 2024Copy number variation analysis in 138 families with steroid-resistant nephrotic syndrome identifies causal homozygous deletions in PLCE1 and NPHS2 in two families.Pediatric nephrology (Berlin, Germany)1 mentions
- 2024Characteristics and Predictors of Apparent Treatment-Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data.American journal of hypertension1 mentions
- 2024Efficacy and safety of glecaprevir and pibrentasvir in Saudi patients with chronic hepatitis C virus infection at a major tertiary hospital.Saudi medical journal1 mentions
- 2024Management and Outcomes of Traumatic Liver Injury: A Retrospective Analysis from a Tertiary Care Center Experience.Healthcare (Basel, Switzerland)1 mentions
- 2024Atypical Complications during the Course of COVID-19: A Comprehensive Review.Medicina (Kaunas, Lithuania)1 mentions
- 2024Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019.Clinical kidney journal1 mentions
- 2024Lipoprotein Glomerulopathy With Complete Resolution With Fenofibrate: Report of First Case From Pakistan.International journal of surgical pathology1 mentions
- 2024Prevalence of Chronic Kidney Disease in People Living With HIV Following in Dammam Medical Complex, Saudi Arabia.Cureus1 mentions
- 2024Ischemic stroke as the initial presentation in acute myeloid leukemia vs. myelodysplastic syndrome: a case report and literature review with pathophysiological and clinical exploration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology1 mentions
- 2024Prevention of dialysis disequilibrium syndrome in children with advanced uremia with a structured hemodialysis protocol: A quality improvement initiative study.Hemodialysis international. International Symposium on Home Hemodialysis1 mentions
- 2024Indole-3 acetic acid induced cardiac hypertrophy in Wistar albino rats.Toxicology and applied pharmacology1 mentions
- 2024The Prevalence of Nephrolithiasis and Associated Risk Factors Among the Population of the Riyadh Province, Saudi Arabia.Cureus1 mentions
- 2024Hemoadsorption: consensus report of the 30th Acute Disease Quality Initiative workgroup.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association1 mentions
- 2024Spilanthes filicaulis (Schumach. & Thonn.) C.D. Adams leaves protects against streptozotocin-induced diabetic nephropathy.PloS one1 mentions
- 2024Characterization of Plant-Derived Natural Inhibitors of Dipeptidyl Peptidase-4 as Potential Antidiabetic Agents: A Computational Study.Pharmaceutics1 mentions
- 2024Molecular Dynamics Simulation of Kir6.2 Variants Reveals Potential Association with Diabetes Mellitus.Molecules (Basel, Switzerland)1 mentions
- 2024Alstrom's Syndrome: An Experience of Tertiary Care Center.Journal of pediatric genetics1 mentions
- 2024Cardiovascular Consequences of Sickle Cell Disease.Journal of blood medicine1 mentions
- 2024Multifaceted Cerebral Venous Thrombosis With Extensive Intra-cerebral Hemorrhage in a Young Man With Mitral Valve Replacement Due to Thrombosis and IgA Nephropathy: A Challenging Case Report From Saudi Arabia.Cureus1 mentions
- 2024Identification of renal protective gut microbiome derived-metabolites in diabetic chronic kidney disease: An integrated approach using network pharmacology and molecular docking.Saudi journal of biological sciences1 mentions
- 2024Efficient deep learning-based approach for malaria detection using red blood cell smears.Scientific reports1 mentions
- 2024Alström Syndrome: A Challenging Case Study of a Female Saudi Patient With Type 2 Diabetes Mellitus and Complete Vision Loss.Cureus1 mentions
- 2024Recessive variants in MYO1C as a potential novel cause of proteinuric kidney disease.Pediatric nephrology (Berlin, Germany)1 mentions
- 2024Quantifying Protein Acetylation in Diabetic Nephropathy from Formalin-Fixed Paraffin-Embedded Tissue.Proteomics. Clinical applications1 mentions
- 2024Impact of preoperative intra-aortic balloon pump on outcomes in coronary artery bypass grafting for unprotected left-main coronary artery disease.Cardiovascular diagnosis and therapy1 mentions
- 2024Bilateral Femoral Neck Fractures in a 50-Year-Old Patient with Chronic Kidney Disease.The American journal of case reports1 mentions
- 2024Evaluating the Effect of Estimating Renal Function With the CKD-EPI 2021 Equation on the ABCD-GENE Score for Clopidogrel Response Prediction.Clinical pharmacology and therapeutics1 mentions
- 2024Overview of Hepatitis B Vaccine Non-Response and Associated B Cell Amnesia: A Scoping Review.Pathogens (Basel, Switzerland)1 mentions