Population record
Saudi Arabia · 11 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Saudi Arabia | “Genetic association between vitamin D receptor gene and Saudi patients confirmed with Familial Hypercholesterolemia. The relation with vitamin D deficiency and vitamin D receptor (VDR) gene is well documented in the Saudi Arabia. AIM: The aim of this study was to investigate the role of molecular analysis studied between FH patients and fours polymorphisms associated with VDR gene in Saudi Population. METHODS: In this case-control study, 120 patients were selected, and 50 patients were confirmed as FH and 70 subjects were confirmed as healthy controls. CONCLUSION: ApaI and BsmI polymorphisms in the VDR gene showed association with FH patients in the Saudi Population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Inducible Nitric Oxide Synthase iNOS-954-G>C and Ex16+14-C>T Gene Polymorphisms and Susceptibility to Vitiligo in the Saudi Population. The present study aimed to investigate the possible association of inducible nitric oxide synthase polymorphisms iNOS-954-G/C (rs1800482 G>C) and iNOS-Ex16+14-C/T (rs2297518 C>T) with vitiligo in the Saudi population, if any. METHODS: We included 120 vitiligo cases and an equal number of age matched healthy controls.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “120 Saudi patients (mean age = 41yrs) diagnosed with true combined EPL participated in this study.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Variants in MEF2A gene in relation with coronary artery disease in Saudi population. This study investigated the association of variants in myocyte enhancer factor 2A (MEF2A) gene with coronary artery disease (CAD) via case control study on Saudi population. The entire (exon 11 putative susceptibility exon) of MEF2A gene was sequenced using direct DNA sequencing method in 120 sporadic patients and 100 controls. None of Saudi subjects (normal as well as diseased) showed 21-bp deletion as reported previously for other populations. We report that MEF2A gene based on SNP rs325400 (G1323T) can be considered as a susceptibility factor for CAD and presence of T allele makes Saudis at more risk to CAD, while other variants detected in this gene do not have any association in Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Study included 120 caregivers of children with CHD visiting the Paediatric Cardiology Clinic that included 93% mothers, aged 31.72 ± 6.67 years, 38.3% Saudi citizens and 45.0% had a high educational level.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Genetic Association of HLA-A*26, -A*31, and -B*51 with Behcet's Disease in Saudi Patients. The objective of this study was to investigate associations of HLA-A and -B alleles with BD in Saudi patients. MATERIALS AND METHODS: Genotyping for HLA-A and HLA-B was performed using HLA genotyping kit (Lab type((R)) SSO) in 120 Saudi subjects, including 60 BD patients and 60 matched healthy controls. CONCLUSION: This study suggests that HLA-A*26, -A*31, and -B*51 are associated with susceptibility risk to BD, while HLA-B*15 may be protective in Saudi patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “ACE I/D and eNOS E298D gene polymorphisms in Saudi subjects with hypertension. SUBJECTS AND METHODS: Participants included 120 Saudi patients with hypertension and 250 normal healthy controls. CONCLUSIONS: There is increased frequency of ACE and eNOS mutant allele carriage among Saudi patients affected with hypertension, particularly if accompanied by obesity and diabetes.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Phylogenetic analysis using d-loop marker of mtDNA of Saudi native chicken strains. This study was carried out to figure the potentiality of d-loop of mitochondrial DNA in discriminating among Saudi native chicken strains and other species of genus Gallus. Our research displayed approximately (26) transition substitutions in nucleotide sequences specific for native chicken strains, whereas it was 120 mutant sites in case of other species of Gallus.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association study between the dopamine-related candidate gene polymorphisms and ADHD among Saudi Arabia population via PCR technique. In Saudi Arabia the prevalence of combined ADHD is 16.4 %. The aim of the present study is to investigate the association between ADHD and polymorphisms of MAOA 30 bp-promoter VNTR and DAT1 40 bp 3' UTRVNTR in Saudi population. PCR technique was employed to detect polymorphisms of MAOA and DAT1 genes in a sample of 120 ADHD subjects and 160 controls. These findings support the hypothesis that some of the MAOA and DAT1 polymorphisms have a causative role in the development of ADHD in the Saudi population. This is the first report investigated the association between MAOA and DAT1 polymorphism at molecular level in Saudi Arabia population as well as Arab world. Therefore further studies are needed to generalize obtained results at Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “BACKGROUND: Colorectal cancer (CRC) is the second most common cancer in the Kingdom of Saudi Arabia with ever increasing incidence rates. METHODS: To gain insight into the molecular mechanisms underpinning CRC in Saudi Arabian patients, we profiled the DNA methylation frequency of key genes (MLH1, MSH2, RASSF1A, SLIT2, HIC1, MGMT, SFRP1, MYOD1, APC, CDKN2A, as well as five CIMP markers) in 120 sporadic CRC cases.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “DNA polymorphisms of the lipoprotein lipase gene and their association with coronary artery disease in the Saudi population. AIM: Our objective of the present investigation was to determine whether 3 LPL polymorphisms (LPL-HindIII, LPL-PvuII and LPL-Ser447Ter) can be considered as independent risk factors for CAD in the Saudi population. METHODS: We recruited 120 CAD subjects, confirmed angiographically with identical ethnic backgrounds and 65 control subjects. It can be concluded that C allele of gene masks the presence of G allele in the Saudi population. Hence this gene also has no significant association with CAD in the Saudi population.” | 0.95 | saudi_context_rules_v1 |