Eastern Province
Saudi Arabia · 67 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Saudi Arabia, Eastern Province | “Prevalence and patterns of cleft lip and palate in Eastern Province of Saudi Arabia: A nine-year retrospective study. AIM: This study aimed to estimate the prevalence and analyze the patterns of cleft lip and/or palate defects among patients referred to King Khalid General Hospital in Hafer Al-Baten, Saudi Arabia. The study highlights the necessity of establishing a national registry for cleft anomalies in Saudi Arabia to improve healthcare planning.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Prevalence and trends of vitamin D deficiency among patients undergoing testing at the Maternity and Children Hospital, Dammam, Eastern Province of Saudi Arabia (2023-2025). Saudi Arabia reports some of the highest burdens across age groups, with national surveys and cohort studies documenting very high combined rates of deficiency and insufficiency. Earlier evidence from the Eastern Province reported very low circulating 25-hydroxyvitamin D levels despite its coastal latitude, suggesting that behavioral and cultural factors may outweigh geographic advantages. CONCLUSION: Vitamin D deficiency and insufficiency remain highly prevalent among patients tested in this mixed hospital-based population in the Eastern Province.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “High prevalence of CTX-M-1 and CTX-M-15 extended-spectrum β-lactamase-producing Escherichia coli in retail imported frozen beef in Saudi Arabia. However, data on the occurrence and molecular characteristics of ESBL-producing E. coli in imported frozen beef in Saudi Arabia remain limited. MATERIALS AND METHODS: A total of 78 imported frozen boneless beef samples were collected from retail shops and supermarkets in Dammam and Al Khobar, Eastern Province, Saudi Arabia. CONCLUSION: Retail imported frozen beef in Saudi Arabia harbors an exceptionally high burden of MDR ESBL-producing E. coli, predominantly driven by CTX-M-1 and CTX-M-15 enzymes.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “A Cross-Sectional Study on the Prevalence of Premature Canities Among University Students in the Eastern Province, Kingdom of Saudi Arabia. Methods: A cross-sectional study was conducted during the academic year 2023-2024 among medical students in a college in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “This study isolated and evaluated pigment-producing fungi from Saudi Arabia's Eastern Province, identifying Sabouraud Dextrose Agar (SDA) as optimal for initial screening.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Prevalence of Asthma Symptoms and Environmental Triggers Among School-Aged Children in the Eastern Province of Saudi Arabia. Indoor environmental exposures such as tobacco smoke, incense use, and carpeting are potential triggers that have not been thoroughly investigated in Saudi Arabia. OBJECTIVES: This study aims to assess the prevalence of asthma symptoms among school-aged children in the Eastern Province of Saudi Arabia and examine their association with specific environmental exposures and familial predisposition. CONCLUSION: This study demonstrates a notable prevalence of asthma symptoms among children in the Eastern Province of Saudi Arabia and identifies key environmental and familial risk factors.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Bayesian estimation of diagnostic accuracy of fecal smears, fecal PCR and serum ELISA for detecting Mycobacterium avium subsp. paratuberculosis infections in four domestic ruminant species in Saudi Arabia. Therefore, we used Bayesian latent class models (BLCMs) to estimate diagnostic accuracy of fecal smears (FS), fecal PCR and serum ELISA for detecting MAP infections in sheep, goats, cattle, and camels older than 2 years in Saudi Arabia. Data from a cross-sectional study conducted in the Eastern Province of Saudi Arabia on 31 different farms with a history of MAP infection were analyzed. Our results suggest that ELISA is a suitable option to identify MAP infected animals in farms with previous history of MAP in the Eastern region of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Hematological Characteristics of Patients With Sickle Cell Disease in Al Ahsa, Saudi Arabia. Therefore, we conducted this study to examine the hematological characteristics of SCD in Saudi Arabia, specifically in the Al Ahsa region. Our study indicates that SCD in Al Ahsa, Saudi Arabia, is associated with moderate-to-severe anemia. These findings should be taken into account when addressing SCD in the eastern province of Saudi Arabia and possibly in other regions.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Awareness and Attitude of Primary School Teachers toward Absence Seizure in the Eastern Province, Saudi Arabia. OBJECTIVES: This research aimed to measure awareness of absence seizures and their effect on academic performance among elementary school teachers in Saudi Arabia's Eastern Province, in addition to measuring their desire to attend awareness-raising workshops that teach them about the disease. A total of 509 elementary school teachers in the eastern province of Saudi Arabia completed a self-administrated online questionnaire. CONCLUSION: Although the vast majority were willing to learn more about absence epilepsy and had a good level of awareness about its effect on academic performance, primary school teachers in Saudi Arabia's Eastern Province demonstrated inadequate knowledge about the disease itself.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Descriptive Analysis of Inpatient Pharmacist Interventions at a Tertiary Care Military Hospital in Eastern Province, Saudi Arabia. Aims This study evaluated the frequency and types of medication errors addressed by in-patient pharmacists, as well as the acceptance of these interventions by physicians at King Fahd Military Medical Complex (KFMMC) in Dhahran, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Isolation of Shiga toxin-producing Escherichia coli O157 and non-O157 from retail imported frozen beef marketed in Saudi Arabia using immunomagnetic separation and multiplex PCR. METHODS: Two hundred and one frozen beef samples were purchased from various supermarkets located in the Eastern Province of Saudi Arabia and subsequently enriched in tryptic soy broth (TSB). CONCLUSIONS: The present study gives a clear perspective on STEC contamination in imported frozen beef marketed in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Knowledge and Awareness of Leukemia Among the Population of Eastern Province, Saudi Arabia. This study aims to evaluate the general knowledge of leukemia and its associated risks among the inhabitants of the Eastern Province, Saudi Arabia. METHODS: A cross-sectional survey was conducted targeting all residents of the Eastern Province, Saudi Arabia, who were Saudi nationals, spanning both genders and aged 15 to 59 years. Future research should aim to overcome study limitations and provide a broader perspective on leukemia awareness throughout Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “We report a case of a 20-year-old Saudi male known to have homozygous sickle cell hemoglobinopathy who was admitted to our institution with abdominal pain. This is the first case reported in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “METHODS AND MATERIALS: A cross-sectional study was a study conducted among adult patients with SCD from the eastern province of Saudi Arabia, where SCD is more widespread than in other regions.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Knowledge of Epilepsy and Seizure First Aid Among Teachers in Eastern Province, Saudi Arabia. BACKGROUND: Epilepsy is one of the most common neurological disorders among patients, with a high prevalence in adults and children in Saudi Arabia. METHODS: A descriptive cross-sectional study was conducted in Eastern Province, Saudi Arabia, targeting teachers in schools of all educational levels using a self-administrated validated questionnaire in Arabic. Exactly 261 (61.7%) teachers were females and 400 (94.6%) were Saudi.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Hemoglobinopathy Patterns in Anemic Patients with a Strong History of Sickle Cell Disease in Eastern Province, Saudi Arabia: A Cross-Sectional Study. <b>Background and Objective:</b> The most common genetic disease in humans is hemoglobinopathies, also known as hemoglobin hereditary diseases. The purpose of this study was to look at the hemoglobinopathy patterns in anemic patients with a history of sickle cell disease in Saudi Arabia's Eastern Province. <b>Materials and Methods:</b> This prospective cross-sectional study was conducted on anemic patients attending the hospital with a strong family history of hemoglobinopathy and general signs and symptoms, as well as mild to moderate anemia crises.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “The study was conducted at the Imam Abdulrahman Bin Faisal University (IAU), Eastern Province, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Methicillin Resistant Staphylococci Isolated from Goats and Their Farm Environments in Saudi Arabia Genotypically Linked to Known Human Clinical Isolates: a Pilot Study. We conducted a pilot whole genome sequencing (WGS) study to characterize the genotypes of nine methicillin resistant staphylococci (MRS) isolates recovered from goats and their farm environments in Eastern Province, Saudi Arabia, between November 2019 to August 2020.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Case report: Restrictive cardiomyopathy presenting with complete thromboembolism occlusion of the terminal part of the abdominal aorta in a preadolescent Saudi girl. We are reporting a preadolescent female from the eastern province of Saudi Arabia who presented with sudden right lower limb swelling, paresthesia, and pain caused by a complete occlusion of the terminal part of the abdominal aorta and both common iliac arteries.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Gut microbiota analyses of Saudi populations for type 2 diabetes-related phenotypes reveals significant association. We analyzed the composition of stool 16S rRNA from 461 T2D and 119 non-T2D participants from the Eastern Province of Saudi Arabia. RESULTS: In this study we performed the largest microbiome study ever conducted in Saudi Arabia, as well as the first-ever characterization of gut microbiota T2D versus non-T2D in this population. CONCLUSION: Based on diabetes status and glucose levels of Saudi participants, relatively stable differences in stool composition were perceived by differential abundance and alpha diversity measures. However, community level differences are evident in the Saudi population between T2D and non-T2D individuals, and diversity patterns appear to vary from well-characterized microbiota from Western cohorts. As a rapidly emerging chronic condition in Saudi Arabia and the Middle East, T2D burdens have grown more quickly and affect larger proportions of the population than any other global region, making a regional reference T2D-microbiome dataset critical to understanding the nuances of disease development on a global scale.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “A retrospective evaluation of side-effects associated with the booster dose of Pfizer-BioNTech/BNT162b2 COVID-19 vaccine among females in Eastern Province, Saudi Arabia. The purpose of the current paper was to explore the side-effects experienced by the females in the Eastern Province of Saudi Arabia directly after receiving the booster dose of the Pfizer-BioNTech/BNT162b2 COVID-19 vaccine. METHODS: A descriptive cross-sectional study among adults living in the East-ern Province, Saudi Arabia was applied.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Virulence Characteristics, Antibiotic Resistance Patterns and Molecular Typing of Enteropathogenic Producing Escherichia coli (EPEC) Isolates in Eastern Province of Saudi Arabia: 2013-2014. INTRODUCTION: The Kingdom of Saudi Arabia has limited data on enteropathogenic Escherichia coli (EPEC). Therefore, this study was undertaken to contribute to EPEC surveillance and investigate the molecular epidemiology of EPEC strains that have been implicated in human infection in King Fahd Hospital of the University (KFHU) between 2013 and 2014 in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Sickle cell disease in the Eastern Province of Saudi Arabia: Clinical and laboratory features.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “We report on the genetic identity of 36 Echinococcus cysts that were collected during a recent slaughterhouse survey of 810 locally bred camels (dromedaries) in the Eastern Province of the Kingdom of Saudi Arabia. The results indicate widespread infection of camels with CE in eastern Saudi Arabia and an active role of camels in the lifecycles of at least E. granulosus s.s.. Complete cox1 haplotype analysis of 21 E. granulosus s.s. isolates shows that the majority of variants circulating in eastern Saudi Arabia is distinct from but closely related to haplotypes from neighboring countries in the Middle East, which indicates the presence of this parasite in KSA for a longer period of time.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Evaluation of the mCIM assay performance for the detection of carbapenemases in Enterobacterales and the identification of the common carbapenemase genes at Eastern Province of Saudi Arabia and Kingdom of Bahrain.Methodology. In Saudi Arabia and Bahrain, OXA-48 was the most prevalent carbapenemase gene followed by NDM.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Quality of Life and the Perceived Impact of Epilepsy in Children and Adolescents in the Eastern Province of the Kingdom of Saudi Arabia. Materials and methods The study included patients with epilepsy aged between and two and 19 years old in three major hospitals in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Direct DNA Sequencing-Based Analysis of Microbiota Associated with Hematological Malignancies in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “This study aimed to identify the common β-globin HBB variants in the population of the Eastern Province, which has the highest prevalence of blood diseases in Saudi Arabia. MATERIAL AND METHODS: Direct sequence of β-globin HBB gene, and alpha-globin HBA1 and HBA2 genes was performed on a total of 545 blood samples (transfusion-dependent: 215, 106 men and 109 women; normal healthy subjects: 330, 197 men and 133 women) collected from Saudi Arabian participants in the Eastern region. RESULTS: A total of 36 variants in HBB gene were revealed with 11 variants that have been reported for the first time in Saudi Arabia, including 7 novel variants that have been identified for the first time in HBB gene.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “In the Eastern province of Saudi Arabia, thalassemia is highly common. Saudi transfusion dependent female β-thalassemia patients with wild alpha globin genotype (αα/αα) were observed with iron level beyond the normal range. However, normal range of iron was observed in transfusion dependent Saudi female beta thalassemia patients co-inherited with double (-α3.7/-α3.7, or --Fil/αα or --MED/αα or - (α) 20.5/αα) or double heterozygosity (- -/-α3.7) alpha globin gene deletions, which is significantly (p < 0.0001) less compared to the Saudi transfused female with wild alpha globin genotype (αα/αα).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Here, we investigate the role of 8 SNPs (not previously studied) in KAI1 gene that could influence its expression in tumor tissue samples of breast cancer patients from the Eastern province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Furthermore, the need for THA following avascular necrosis in the Eastern Province of Saudi Arabia is high, and the subsequent risk of periprosthetic fracture is prevalent. Aim of the study This cross-sectional retrospective study aimed to assess the prevalence and associated risk factors for periprosthetic fractures during total hip arthroplasty in sickle cell disease patients at King Fahad Hospital Hofuf, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Antibiotic resistance and molecular characterization of enteroaggregative Escherichia coli isolated from patients with diarrhea in the Eastern Province of Saudi Arabia. METHODS: There were 63 non-duplicate isolates of E. coli isolated from diarrheal cases in teaching hospital in Eastern Province of Saudi Arabia between May 2013 to July 2014. CONCLUSION: EAEC was detected for the first time, among Saudi patients with diarrhea in this region of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “The course of patients with SCD who developed ESRD and started dialysis at two centers in the Eastern Province of Saudi Arabia was retrospectively analyzed.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “BACKGROUND: Sickle cell disease (SCD) is a common disease in the Eastern province of Saudi Arabia. SETTING: Outpatient clinics in the Eastern province over a 9-month duration from July 2014 to March 2015.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “In our previous study of the prevalence of β-thalassemia mutations in the Eastern Province of Saudi Arabia, we confirmed the widespread coinheritance of α-thalassemia mutation.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “A Comparative Analysis of Breast and Ovarian Cancer-related Gene Mutations in Canadian and Saudi Arabian Patients with Breast Cancer. Previous reports have indicated that patients with breast cancer who are from the Eastern Province of Saudi Arabia have a different gene expression profile from that known for their age-matched North American population. In the present study, breast tumor samples from Canadian and Saudi Arabian patients were screened for known and unknown mutations within BRCA1 and BRCA2 as well as 21 additional genes, including, ATM, BARD1, CDH1, P53, EPCAM, MSH6, and RAD50, which have been implicated in breast and ovarian cancer predisposition. Forty-one mutations in 18 genes were unique to the Canadian population and 59 mutations in 20 genes were unique to the Saudi Arabian population. Unique to this work is the identification of mutations frequently found in the Saudi Arabian population that are rare in the Canadian population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “The impact of built environment on diabetic patients: the case of Eastern Province, KIngdom of Saudi Arabia. The Kingdom of Saudi Arabia (KSA) is one of top ten countries in the prevalence of diabetes.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “To determine the prevalence of these mutations in Saudi patients with ESRD on hemodialysis, we studied the allelic frequency and genotype distribution in patients receiving hemodialysis and in a control group, all residing in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Molecular bases of beta-thalassemia in the Eastern Province of Saudi Arabia. beta-thalassemia is a group of heterogeneous recessive disorders common in many parts of the world. Al-Qatif and Al-Hassa oases in the Eastern Province of Saudi Arabia are regions known for high frequency of these disorders.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Geographical distribution of congenital heart defects in Saudi Arabia. METHODS: The geographical distribution of 5 865 Saudi Arabian nationals with CHD was studied by cross-matching their residential provinces and towns with a geographical information system provided by the General Directorate for Military Survey. Thematic maps of the distribution of the CHD burden highlighted the southwestern provinces, nearthe border with Yemen, and the northeast section of the Eastern Province. CONCLUSIONS: Patterns of disease in Saudi Arabia are best studied at the level of individual towns and villages. Southwestern Saudi Arabia and the northern part of the Eastern Province appear to exhibit a higher burden of CHD.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in the Eastern Province of Saudi Arabia. The level of activity of the enzyme glucose-6-phosphate dehydrogenase (G6PD) was determined in 154 unrelated Saudi males and females with G6PD deficiency who were residing in the Eastern Province of Saudi Arabia. The data indicate that the G6PD Mediterranean mutation is the most common (84%) in the Eastern Province, followed by G6PD A- (5.8%).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Massive splenic infarction in Saudi patients with sickle cell anemia: a unique manifestation. Massive splenic infarction is a rare and unique complication of SCA in the Eastern Province of Saudi Arabia, and for early diagnosis and treatment, physicians caring for these patients should be aware of such a complication.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Acute chest syndrome in sickle cell disease in Saudi Arab Children in the Eastern Province. BACKGROUND: This study was conducted to define the clinical features and outcome of acute chest syndrome (ACS) in sickle cell disease (SCD) patients in the Eastern Province of Saudi Arabia. CONCLUSION: Acute chest syndrome in children with sickle cell disease in the Eastern Province of Saudi Arabia is relatively mild and infrequent, and rarely associated with bacteremia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Hemoglobin H disease in the Al-Qatif Region of Saudi Arabia. BACKGROUND: The Al-Qatif region in the Eastern province of Saudi Arabia has the highest prevalence of a-thalassemia genes in the Kingdom. CONCLUSION: Hemoglobin H disease is not uncommon in the Al-Qatif region of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “This study was conducted on the Saudi population from different regions of Saudi Arabia to determine the frequency of sickle cell gene (Hb S). The highest frequency (0.149) was found in Al-Qateef, an eastern province of Saudi Arabia, and the lowest (0.001) were found in the central region.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Prevalence of mitral valve prolapse in Saudi sickle cell disease patients in Dammam - A prospective-controlled echocardiographic study. Since SCD is very common in the Eastern Province of Saudi Arabia, we undertook a prospective controlled study to determine and compare the prevalence of MVP in the SCD patients with other groups of subjects.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Community survey of neurological disorders in Saudi Arabia: Results of the pilot study in Agrabiah. A pilot study of the Agrabiah area in Al-Khobar was undertaken to field test study methodologies and identify possible limitations and constraints to a planned community survey for neurological disorders in the Eastern Province of Saudi Arabia. Our results show that a community survey for neurological disorders is feasible in Saudi Arabia and the modified questionnaire was a good screening instrument (sensitivity 94.7%, specificity 96.8%). These factors should be considered when planning community surveys in Saudi Arabia and other environments with similar sociocultural settings.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Evidence from structural studies of DNA suggest that the sickle cell mutation has arisen on at least three separate occasions in Africa and as a fourth independent mutation in the Eastern Province of Saudi Arabia or India.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “In Saudi Arabia two major forms of sickle cell anaemia (SCA) have been identified, a benign SCA is reported mainly in the Eastern province and a severe form is reported in other parts of the country. We initiated studies in the different regions of Saudi Arabia. Our studies on the Saudi population from different regions of the country using Hinc II and Hind III showed that the beta-globin gene haplotype ++-++ is associated with a mild sickle cell anaemia, while ----+ is associated with the severe form of the disease. This paper presents and compares the two major forms of SCA in Saudi population and relates it to the genetic heterogeneity.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Osteomyelitis and septic arthritis in sickle cell disease in the eastern province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Trachoma in eastern province of Saudi Arabia. Trachoma is one of the main cause of curable/preventable blindness in Saudi Arabia. 1955-65 in Eastern Province revealed prevalence rate of trachoma as 100% in Al Hasa, 98.0% in Qatif Oasis and 93.0% in Qatif town dwellers. Preliminary study by Ministry of Health, Eastern Province in 1986 revealed 3.74% of the population blind showing 10.1% due to trachoma. In 1986, Ministry of Health established Regional Prevention of Blindness & Ophthalmic Medical Education Committee, Eastern Province with six sub-divisions in Al Hasa, Qatif, Dammam, Al Khobar/Dhahran, Jubail and Hafr Al Batin. Ministry of Health is in process of developing the Trachoma Center in Qatif region as well as comprehensive eye care by completing preliminary tertiary level care Eye Hospital in Dhahran to reduce the incidence of active trachoma below 0.5% within the next five years; thus achieve the goal of Prevention of Blindness in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Clinical features of sickle cell disease in eastern Saudi Arab children. The clinical features of sickle cell disease (SCD) in Saudi Arab children of eastern origin are presented. We conclude that SCD in children of eastern origin is clinically milder than earlier descriptions from the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Variability of sickle cell disease in the Eastern Province of Saudi Arabia. The clinical and hematologic features of sickle cell disease in two groups of patients of different ancestral origin, but living in the Eastern Province of Saudi Arabia, are presented. Despite being born and living in the same environment (Eastern Province), patients of southwestern origin had more severe clinical features, consistently lower hemoglobin levels, and higher reticulocyte counts, suggesting more severe hemolysis. We conclude that there are at least two distinct forms of sickle cell disease in the Eastern Province of Saudi Arabia and that the variability of the disease in early childhood is more likely related to genetic than to environmental factors.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Colorimetric determinations of glycosylated Hb were carried out in a sample (n = 97) of sickle cell anemia patients, and in an age- and sex-matched group of individuals (n = 45) heterozygous for sickle cell anemia, from the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Plasma zinc concentrations were determined in patients with sickle cell anemia and in disease free controls in the Eastern province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Alpha-thalassemia and Hb E in the eastern province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “The ecological context of child health in Saudi Arabia. The general background to child health in Saudi Arabia is reviewed. Thus, the prevalence of alpha thalassemia is reported at 50 percent, and the sickle cell trait at 4.4-20 percent in sample surveys from the Eastern Province. It is emphasized that demographic and epidemiological information from Saudi Arabia is scarce and frequently uncertain, and that further studies are needed to identify the health needs of Saudi children.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Interaction of alpha-thalassemia with other hemoglobinopathies in the eastern province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Homozygous sickle cell disease and priapism in the eastern province of Saudi Arabia. Two adult sickle cell homozygotes from the eastern oases of the Kingdom of Saudi Arabia presented with severe persistent priapism.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “The beta(s) globin gene was found to be linked almost exclusively to a beta(S) haplotype ( -++-), which is also common in Saudi Arabian patients from the Eastern Province (referred to as the Asian beta(s) haplotype).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined. Homozygous sickle cell disease in the eastern province of Saudi Arabia is clinically mild. To determine whether these sickle cell anemia patients inherit an increased capacity to synthesize fetal hemoglobin, a radioimmunoassay of fetal and adult hemoglobin was performed on erythroid progenitor (BFU-E)-derived erythroblasts from Saudi Arabian sickle cell patients and their parents. Mean fetal hemoglobin content per BFU-E-derived erythroblast from Saudi Arabian sickle cell patients was 6.2 +/- 2.4 pg/cell or 30.4 +/- 8.6% fetal hemoglobin (normal 1.1 +/- 0.7 pg/cell and 5.1 +/- 1.8%). Despite virtually normal HbF levels in sickle trait parents of these Saudi patients, mean fetal hemoglobin production per BFU-E-derived erythroblast in these individuals was elevated to 3.42 +/- 1.79 pg/cell or 16.1 +/- 6.4% fetal hemoglobin, and the magnitude of fetal hemoglobin production found in parents correlated with that of the patients. These data indicate that the high fetal hemoglobin in Saudi sickle cell disease is genetically determined but expressed only during accelerated erythropoiesis.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Glycosylated hemoglobin levels in a benign form of sickle cell anemia in Saudi Arabia. Glycosylated hemoglobin was determined by the thiobarbituric acid method in sickle cell anemia patients from the Eastern Province of Saudi Arabia. The level of glycosylated hemoglobin in a Saudi SS sample (4.36%, SD 0.83) is 90% of that of the sample of normals (4.85%, SD 0.51). The fetal hemoglobin level in Saudi sickle cell patients was 12.03% (SD 4.84), which is significantly different from that of Americans of African origin at p = 0.001. The reported positive relationship between the percentages of glycosylated Hb and Hb F in American Blacks seems to be valid in the Saudi population only up to the level of 10-12% of fetal hemoglobin. The 2,3-diphosphoglycerate value in Saudi Hb SS adults was 21.7 mumol/g (SD 7.4) and accordingly only twice as high as that of normal individuals. The benign clinical course exhibited by Saudi sickle cell patients is reflected by the survival of the RBC as indexed by its content of glycosylated Hb and 2,3-diphosphoglycerate. Moreover 10-12% of fetal hemoglobin in the RBC seems sufficient to ameliorate the severity of this disease in patients from the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Hypersplenism in homozygous sickle-cell disease in Saudi Arabia. In the Eastern Province of Saudi Arabia, sickle-cell disease runs a benign course.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Neonatal screening for sickle cell disease in the Eastern Province of Saudi Arabia. Neonatal screening for sickle cell disease has been established in three hospitals in the Eastern Province of Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Sickle cell haemoglobinopathy and Salmonella osteomyelitis in the eastern province of Saudi Arabia. Four cases of Salmonella osteomyelitis in children with sickle cell haemoglobinopathy were seen at a hospital in the Eastern Province of Saudi Arabia. These cases are of interest as the Saudi variety of sickle cell anemia has been previously reported to have a relatively uncomplicated course.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia, Eastern Province | “Human haemoglobins and haemoglobinopathies in Arabia: Hb O Arab in Saudi Arabia. With the exception of the eastern province of Saudi Arabia, where several aspects of the sickle-cell disease have been focused upon, few reports have appeared in the literature. In the present report we describe the first finding of Hb O Arab in Saudi Arabia, which may shed more light on the anthropological significance of this haemoglobin variant.” | 0.95 | saudi_context_rules_v1 |