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Phenotype profile

COVID-19

SaudiVarKB evidence summary derived from retained literature mentions.

1,095Phenotype mentions
100Publications
50Associated gene records
50Associated variant records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
ACE2HGNC:135576565
TMPRSS2HGNC:118761212
ACEHGNC:270777
ABOHGNC:7955
NLRP3HGNC:1640044
CRPHGNC:236744
HLA-DRB1HGNC:494844
HLA-BHGNC:493244
TLR7HGNC:1563144
TLR4HGNC:1185044
HLA-AHGNC:493144
G6PDHGNC:405733
IRF7HGNC:612233
TLR2HGNC:1184833
TNFHGNC:1189222
STAT3HGNC:1136422
STAT1HGNC:1136222
MTHFRHGNC:743622
PTGS2HGNC:960522
IMPACTHGNC:2038722
INSHGNC:608122
TP53HGNC:1199822
VDRHGNC:1267922
STAT2HGNC:1136322
BCL2L1HGNC:99222
HLA-DQB1HGNC:494422
TLR3HGNC:1184922
CXCL10HGNC:1063722
ZFP36HGNC:1286222
CCL2HGNC:1061822
SERPINA5HGNC:872322
CFHHGNC:488322
CD46HGNC:695322
MAVSHGNC:2923322
DPP4HGNC:300922
TBK1HGNC:1158422
IRF3HGNC:611822
IFNAR2HGNC:543322
HLA-GHGNC:496422
IFITM3HGNC:541422
CD27HGNC:1192222
ICAM1HGNC:534422
PARP1HGNC:27011
CXCL9HGNC:709811
CD4HGNC:167811
CDKN1AHGNC:178411
APOEHGNC:61311
KNG1HGNC:638311
AK2HGNC:36211
WT1HGNC:1279611

Associated variant records

Co-mentioned in the same publications
VariantIdentifier / contextArticlesMentions
D614GD614G1111
N501YN501Y66
L452RL452R55
K417NK417N44
E484KE484K33
A23403GA23403G33
C3037TC3037T33
C14408TC14408T33
Q57HQ57H33
R203KR203K33
G204RG204R33
T478KT478K22
C241TC241T22
P323LP323L22
N969KN969K22
E484QE484Q22
G476SG476S22
p.Gln462Terp.Gln462Ter11
p.Trp151Terp.Trp151Ter11
rs1800629rs180062911
rs2230054rs223005411
I120TI120T11
rs1800629rs180062911
H63DH63D11
rs4646994rs464699411
rs3813082rs381308211
rs2228570rs222857011
p.F8Sp.F8S11
p.Arg288Trpp.Arg288Trp11
Q498RQ498R11
rs16944rs1694411
R717LR717L11
P681RP681R11
rs1143634rs114363411
rs1800795rs180079511
G8790AG8790A11
rs2285666rs228566611
rs1057079rs105707911
rs3136516rs313651611
rs6042rs604211
rs6123rs612311
rs371194629rs37119462911
rs1707rs170711
rs1710rs171011
rs17179101rs1717910111
rs17179108rs1717910811
rs1063320rs106332011
rs9380142rs938014211
rs1610696rs161069611
K211EK211E11

Associated population records

Co-mentioned in the same publications

Supporting publications

100 records
  1. 2026Outcome and Safety of Insulin in the Management of Smell Loss: A Systematic Review.Ear, nose, & throat journal1 mentions
  2. 2026Exploring natural compounds and synthetic derivatives as potential inhibitors of SARS-CoV-2 PLpro: a computational approach with enzyme inhibition and cytotoxicity assessment.Journal of biomolecular structure & dynamics1 mentions
  3. 2026Mechanisms of azithromycin resistance in Salmonella Typhi: molecular insights from dynamics behavior to clinical implications.Journal of biomolecular structure & dynamics1 mentions
  4. 2026Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America1 mentions
  5. 2026Study of Interferon-Induced Transmembrane Protein 3 Gene Polymorphism and Serum Interferon-λ3 Level in COVID-19.International journal of immunogenetics1 mentions
  6. 2026HIV/AIDS in transition: Global disparities, Africa's uneven progress and struggles, and the emerging threat of funding cuts (global burden of disease study, 1990-2021).HIV medicine1 mentions
  7. 2026Antimicrobial Potential of Commercially Produced Citronella Oil: An In Vitro and In Silico Investigation.Current drug targets1 mentions
  8. 2026Clinical and inflammatory predictors of ICU admission and mortality in COVID-19: A retrospective multi-center cohort study from Saudi Arabia.Medicine1 mentions
  9. 2026Hybrid feature selection with novel deep learning model for COVID-19 risk prediction.Scientific reports1 mentions
  10. 2026Hybrid modeling and forecasting of COVID-19: integrating SEAIQHRD and GPR for improved predictions.BMC infectious diseases1 mentions
  11. 2026An efficient dual path deep learning framework for COVID-19 classification using lung CT scans with explainable AI.Scientific reports1 mentions
  12. 2026IFNAR2 p.F8S Variant Associates with Severe COVID-19 and Adaptive Immune Cell Activation Modulation.International journal of molecular sciences1 mentions
  13. 2026Co-infection of SARS-CoV-2 and DENV case report in Jazan Region Southwest Saudi Arabia.BMC infectious diseases1 mentions
  14. 2026Functional tics and tic-like behaviors.Handbook of clinical neurology1 mentions
  15. 2026Internet of Medical Things Enabled Multimodal Framework: Deep Machine Learning for Chronic Cardiac Disease Prediction in Healthcare 5.0.Healthcare technology letters1 mentions
  16. 2026Distinct mutational landscapes and phylogenomic insights of the SARS-CoV-2 delta variant in Pakistan and India: Regional evolution, novel mutations, and epidemiological implications.PloS one1 mentions
  17. 2026Harnessing artificial intelligence for automatic feedback in a virtual anatomy study tool: A Q-methodology study.Anatomical sciences education1 mentions
  18. 2026Clinical Outcomes with the Use of Dipeptidyl Peptidase-4 (DPP-4) Inhibitor Among Patients with Diabetes Mellitus and COVID-19: A Systematic Review of Observational Studies.Journal of clinical medicine1 mentions
  19. 2026Decoding Microbiota-Immune Interplay in Viral Pathogenesis: Toward Next-Generation Antiviral Therapies.Probiotics and antimicrobial proteins1 mentions
  20. 2026Complications in acute respiratory distress syndrome: a systematic review and meta-analysis.Critical care (London, England)1 mentions
  21. 2026Leber hereditary optic neuropathy triggered by the AstraZeneca coronavirus disease 2019 vaccination.Oman journal of ophthalmology1 mentions
  22. 2026Neuropsychiatric Sequelae of COVID-19: A Systematic Review of Acute and Prolonged Effects.CNS & neurological disorders drug targets1 mentions
  23. 2026Work-related musculoskeletal disorders among gig-based food delivery workers: a systematic review and meta-analysis.Frontiers in public health1 mentions
  24. 2026Tuberculosis surveillance indicators and chest radiograph phenotype clustering in southwestern Saudi Arabia, 2010-2020.Tropical medicine and health1 mentions
  25. 2026Vaccine effectiveness across the Omicron evolutionary spectrum (BA.2, BA.5, XBB, JN.1, KP.3): a systematic review of studies published 2022-2025.BMC infectious diseases1 mentions
  26. 2026A case report on the effective and safe use of ravulizumab in atypical hemolytic uremic syndrome during pregnancy.BMC nephrology1 mentions
  27. 2026Bio-inspired chemometric methods for simultaneous UV spectrophotometric determination of molnupiravir, nirmatrelvir, and favipiravir in pharmaceutical formulations and environmental samples.Scientific reports1 mentions
  28. 2026Epidemiology of pediatric invasive group A streptococcus infection in a Saudi tertiary care center.Annals of Saudi medicine1 mentions
  29. 2026Targeting SARS-CoV-2 main protease (3CLpro) with Paeonia-derived phytochemicals.In silico pharmacology1 mentions
  30. 2026Safety and efficacy of COVID-19 vaccines in pregnant and lactating women: a comprehensive review.Inflammopharmacology1 mentions
  31. 2026Denys-Drash Syndrome by WT1 Gene: Clinical Variability and Management Challenges in Two Saudi Infants.Case reports in endocrinology1 mentions
  32. 2026COVID-19 vaccine-associated liver injury and autoimmune hepatitis: a case series.Annals of medicine and surgery (2012)1 mentions
  33. 2026Smartphone use and related factors with hand pain among university students: a systematic review.BMC musculoskeletal disorders1 mentions
  34. 2026Affinity-matured B cell responses neutralizing type-I interferons underlie severe viral infections.Cell1 mentions
  35. 2026Mesenchymal stem cell derived exosomes mitigate COVID-19 cytokine storm via Annexin A1 and TGF-β mediated MAPK pathway inhibition.Stem cell research & therapy1 mentions
  36. 2026Insights into prospective antiviral activities of algal polysaccharides along with their properties, extraction, and characterization: A review.International journal of biological macromolecules1 mentions
  37. 2026Sudden sensorineural olfactory loss: a structured narrative review and proposal for a standardised terminological framework.Frontiers in surgery1 mentions
  38. 2026Biochemical insights and microRNA profiling via next-generation sequencing in moderate and severe COVID-19 cases.Clinics (Sao Paulo, Brazil)1 mentions
  39. 2026Immunogenetic modulation of endothelial inflammation by the LIPG -384A/C promoter variant influences COVID-19 severity.Frontiers in immunology1 mentions
  40. 2026Association between residential greenness and the risk of inflammatory bowel disease in patients with COVID-19: A Korean nationwide cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
  41. 2026HLA Class I and II Variants as Potential Determinants of Clinical Severity and Mortality in Patients with COVID-19: A Prospective Study from Saudi Arabia.Biomedicines1 mentions
  42. 2026Predictive biomarkers of COVID-19 impact in renal transplant patients: an exploratory proteomic and cytokine analysis.Frontiers in immunology1 mentions
  43. 2025Campesterol and dithymoquinone as a potent inhibitors of SARS cov-2 main proteases-promising drug candidates for targeting its novel variants.Journal of biomolecular structure & dynamics1 mentions
  44. 2025Molecular dynamic analyses of the interaction of SARS-CoV-1 or 2 variants with various angiotensin-converting enzyme-2 species.Journal of biomolecular structure & dynamics1 mentions
  45. 2025Decoding and Unravelling Mpox, Herpes, and Syphilis Infections: A State of Art Review.Current pharmaceutical biotechnology1 mentions
  46. 2025The intersection of microbiome and autoimmunity in long COVID-19: Current insights and future directions.Cytokine & growth factor reviews1 mentions
  47. 2025Relationships Between Polymorphisms in HLA-G 3'UTR Region and COVID-19 Disease Severity.Biochemical genetics1 mentions
  48. 2025Depression unveiled: Insights into etiology and animal models for behavioral assessment, exploring the multifactorial nature and treatment of depression.Brain research1 mentions
  49. 2025Identification of Novel Genomic Variants in COVID-19 Patients Using Whole-Exome Sequencing: Exploring the Plausible Targets of Functional Genomics.Biochemical genetics1 mentions
  50. 2025Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals.mBio1 mentions
  51. 2025Intrinsic Factors Behind the Long-COVID: V. Immunometabolic Disorders.Journal of cellular biochemistry1 mentions
  52. 2025Ongoing Evolution of Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2023-2024.Emerging infectious diseases1 mentions
  53. 2025Modeling the potential public health and economic impact of different COVID-19 vaccination strategies with an adapted vaccine in the Kingdom of Saudi Arabia.Expert review of vaccines1 mentions
  54. 2025Exploring pyrazolines as potential inhibitors of NSP3-macrodomain of SARS-CoV-2: synthesis and in silico analysis.Scientific reports1 mentions
  55. 2025Integrated in Silico and in Vitro Studies of Rutin's Potential against SARS-CoV-2 through the Inhibition of the RNA-dependent RNA Polymerase.Current medicinal chemistry1 mentions
  56. 2025SARS-CoV-2 excretion and genetic evolution in nasopharyngeal and stool samples from primary immunodeficiency and immunocompetent pediatric patients.Virology journal1 mentions
  57. 2025Emergence of a blaNDM-5-carrying extensively drug-resistant Enterobacter cloacae ST1718 in Saudi Arabia: Insights from comprehensive genome analysis.Journal of infection and public health1 mentions
  58. 2025Angiotensin-Converting Enzyme 2 (G8790A) Gene Polymorphism as a Risk Factor for COVID-19 in Egyptian Children and Adolescents.Pediatric pulmonology1 mentions
  59. 2025A 10 Year Long-Lived Cellular and Humoral MERS-CoV Immunity Cross-Recognizing the Wild-Type and Variants of SARS-CoV-2: A Potential One-Way MERS-CoV Cross-Protection Toward a Pan-Coronavirus Vaccine.Journal of medical virology1 mentions
  60. 2025Correction: Identification of Novel Genomic Variants in COVID-19 Patients Using Whole-Exome Sequencing: Exploring the Plausible Targets of Functional Genomics.Biochemical genetics1 mentions
  61. 2025An integrated theoretical study on natural alkaloids as SARS-CoV-2 main protease inhibitors: a step toward discovery of potential drug candidates with anti-COVID-19 activity.RSC advances1 mentions
  62. 2025Unlocking the Potential of RNA Sequencing in COVID-19: Toward Accurate Diagnosis and Personalized Medicine.Diagnostics (Basel, Switzerland)1 mentions
  63. 2025Methicillin-Resistant Staphylococcus aureus: The Shifting Landscape in the United Arab Emirates.Antibiotics (Basel, Switzerland)1 mentions
  64. 2025Uncovering the Binding Mechanism of Mutated Omicron Variants via Computational Strategies.ACS omega1 mentions
  65. 2025Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry.PloS one1 mentions
  66. 2025Humoral and cellular immune durability of different COVID-19 vaccine platforms following homologous/heterologous boosters: one-year post vaccination.Frontiers in immunology1 mentions
  67. 2025Facial Nerve Palsy Amid the SARS-CoV-2 Pandemic: A Pooled Analysis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale1 mentions
  68. 2025Depression, anxiety, and stress among HIV-positive pregnant women during the COVID-19 pandemic: a hospital-based cross-sectional study in India.BMC pregnancy and childbirth1 mentions
  69. 2025SARS-CoV-2 S, M, and E Structural Glycoproteins Differentially Modulate Endoplasmic Reticulum Stress Responses.International journal of molecular sciences1 mentions
  70. 2025SARS-CoV-2 Variants: Genetic Insights, Epidemiological Tracking, and Implications for Vaccine Strategies.International journal of molecular sciences1 mentions
  71. 2025Detection of SARS-CoV-2 in nasopharyngeal swab samples from COVID-19 patients in Riyadh, Saudi Arabia: a PCR-based study.Virology journal1 mentions
  72. 2025Discovering broad-spectrum inhibitors for SARS-CoV-2 variants: a cheminformatics and biophysical approach targeting the main protease.Frontiers in pharmacology1 mentions
  73. 2025Fortifying defenses: Tactical safety protocols for COVID-19 sub-variant JN.1 in healthcare and laboratory settings.Journal of family medicine and primary care1 mentions
  74. 2025Comparison of Phenotypes of Headaches After COVID-19 Vaccinations Differentiated According to the Vaccine Used.Vaccines1 mentions
  75. 2025The comprehensive insights into the B-cells-mediated immune response against COVID-19 infection amid the ongoing evolution of SARS-CoV-2.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie1 mentions
  76. 2025Addressing the global challenge of bacterial drug resistance: insights, strategies, and future directions.Frontiers in microbiology1 mentions
  77. 2025Public perception of COVID-19 in Saudi Arabia during the Omicron wave: recommendations for policy improvement.Frontiers in public health1 mentions
  78. 2025In-Utero Maternal-to-Fetal Transmission of COVID-19: An Immunological and Virological Study in the Eastern Province of Saudi Arabia.Infection and drug resistance1 mentions
  79. 2025Impact of ultraviolet radiation on filtering facepiece respirators and SARS-CoV-2 detection.Frontiers in public health1 mentions
  80. 2025Comprehensive review of thrombophilia: pathophysiology, prevalence, risk factors, and molecular diagnosis.Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine1 mentions
  81. 2025Trends in CT pulmonary angiography utilization and recurrent imaging in sickle cell disease: a longitudinal study.International journal of emergency medicine1 mentions
  82. 2025Recent SARS-CoV-2 evolution trajectories indicate the emergence of Omicron's several subvariants and the current rise of KP.3.1.1 and XEC.Virology1 mentions
  83. 2025Silaproline-bearing nirmatrelvir derivatives are potent inhibitors of the SARS-CoV-2 main protease highlighting the value of silicon-derivatives in structure-activity-relationship studies.European journal of medicinal chemistry1 mentions
  84. 2025The essential role of prebiotics in restoring gut health in long COVID.Progress in molecular biology and translational science1 mentions
  85. 2025More antibodies are not always better: Fc effector functions play a critical role in SARS-CoV-2 infection and protection.Progress in molecular biology and translational science1 mentions
  86. 2025The impact of maternal stress on non-syndromic clefts: a retrospective case-control study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry1 mentions
  87. 2025SARS-COV-2 causes significant abnormalities in the fibrinolysis system of patients: correlation between viral mutations, variants and thrombosis.Frontiers in cellular and infection microbiology1 mentions
  88. 2025Predicting digital contact tracing tool adoption during COVID-19 from the perspective of TAM: The role of trust, fear, privacy, anxiety, and social media.Digital health1 mentions
  89. 2025Prevalence of azithromycin resistance after the COVID-19 era in clinical bacterial isolates from a tertiary care hospital in Gurugram, India.Frontiers in microbiology1 mentions
  90. 2025FokI polymorphism of the vitamin D receptor gene: Linking COVID-19 risk to genetic susceptibility in children.Cytokine1 mentions
  91. 2025Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway.Stem cell research & therapy1 mentions
  92. 2025Retraction Note: COVID-19 diagnostic methods in developing countries.Environmental science and pollution research international1 mentions
  93. 2025Intrinsic Factors Behind Long COVID: VI. Combined Impact of G3BPs and SARS-CoV-2 Nucleocapsid Protein on the Viral Persistence and Long COVID.Journal of cellular biochemistry1 mentions
  94. 2025Intrinsic factors behind long COVID: exploring the role of nucleocapsid protein in thrombosis.PeerJ1 mentions
  95. 2025Repositioning antivirals against COVID-19: Synthetic pathways, mechanisms, and therapeutic insights.Microbial pathogenesis1 mentions
  96. 2025Sulfonohydrazide as a potential inhibitor of SARS-CoV-2 infection.Scientific reports1 mentions
  97. 2025Cohort profile: characterisation, determinants, mechanisms and consequences of the long-term effects of COVID-19 - providing the evidence base for health care services (CONVALESCENCE) in the UK.BMJ open1 mentions
  98. 2025Innate immunity, therapeutic targets and monoclonal antibodies in SARS-CoV-2 infection.PeerJ1 mentions
  99. 2025Biochemical insight into gut microbial imbalance in Covid-19 and post vaccination heart attacks.World journal of microbiology & biotechnology1 mentions
  100. 2025Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions