stroke
SaudiVarKB evidence summary derived from retained literature mentions.
517Phenotype mentions
100Publications
50Associated gene records
50Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| MTHFR | HGNC:7436 | 9 | 9 |
| CYP2C19 | HGNC:2621 | 7 | 7 |
| NOTCH3 | HGNC:7883 | 6 | 6 |
| APOE | HGNC:613 | 3 | 3 |
| CYP3A4 | HGNC:2637 | 3 | 3 |
| ADA2 | HGNC:1839 | 3 | 3 |
| CYP3A5 | HGNC:2638 | 3 | 3 |
| PCSK9 | HGNC:20001 | 3 | 3 |
| JAK2 | HGNC:6192 | 3 | 3 |
| VWF | HGNC:12726 | 2 | 2 |
| HBB | HGNC:4827 | 2 | 2 |
| BCL11A | HGNC:13221 | 2 | 2 |
| G6PD | HGNC:4057 | 2 | 2 |
| ABCB1 | HGNC:40 | 2 | 2 |
| LDLR | HGNC:6547 | 2 | 2 |
| ACE | HGNC:2707 | 2 | 2 |
| TLR4 | HGNC:11850 | 2 | 2 |
| MPL | HGNC:7217 | 2 | 2 |
| COL4A2 | HGNC:2203 | 2 | 2 |
| SIRT1 | HGNC:14929 | 1 | 1 |
| NLRP3 | HGNC:16400 | 1 | 1 |
| SLC2A10 | HGNC:13444 | 1 | 1 |
| ENPP1 | HGNC:3356 | 1 | 1 |
| PSEN2 | HGNC:9509 | 1 | 1 |
| APOA5 | HGNC:17288 | 1 | 1 |
| GLA | HGNC:4296 | 1 | 1 |
| PRKAG2 | HGNC:9386 | 1 | 1 |
| DIAPH1 | HGNC:2876 | 1 | 1 |
| SOD1 | HGNC:11179 | 1 | 1 |
| DNMT3A | HGNC:2978 | 1 | 1 |
| KLF14 | HGNC:23025 | 1 | 1 |
| DOCK8 | HGNC:19191 | 1 | 1 |
| CBS | HGNC:1550 | 1 | 1 |
| TET2 | HGNC:25941 | 1 | 1 |
| HMOX1 | HGNC:5013 | 1 | 1 |
| PINK1 | HGNC:14581 | 1 | 1 |
| PTGS2 | HGNC:9605 | 1 | 1 |
| FMR1 | HGNC:3775 | 1 | 1 |
| TCF7L2 | HGNC:11641 | 1 | 1 |
| CTSA | HGNC:9251 | 1 | 1 |
| ABO | HGNC:79 | 1 | 1 |
| CYP1A2 | HGNC:2596 | 1 | 1 |
| CYP2B6 | HGNC:2615 | 1 | 1 |
| CCR5 | HGNC:1606 | 1 | 1 |
| ADGRV1 | HGNC:17416 | 1 | 1 |
| CPS1 | HGNC:2323 | 1 | 1 |
| CD59 | HGNC:1689 | 1 | 1 |
| ADAMTS13 | HGNC:1366 | 1 | 1 |
| IGFBP7 | HGNC:5476 | 1 | 1 |
| EGF | HGNC:3229 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| G1691A | G1691A | 3 | 3 |
| C677T | C677T | 3 | 3 |
| rs1801133 | rs1801133 | 2 | 2 |
| rs1333048 | rs1333048 | 2 | 2 |
| A1298C | A1298C | 1 | 1 |
| rs333 | rs333 | 1 | 1 |
| p.Gly310Glu | p.Gly310Glu | 1 | 1 |
| c.1447-1451del | c.1447-1451del | 1 | 1 |
| M.3243A>G | M.3243A>G | 1 | 1 |
| rs7482144 | rs7482144 | 1 | 1 |
| c.3009G>T | c.3009G>T | 1 | 1 |
| p.Trp1003Cys | p.Trp1003Cys | 1 | 1 |
| G20210A | G20210A | 1 | 1 |
| rs2071746 | rs2071746 | 1 | 1 |
| p.Arg987Ter | p.Arg987Ter | 1 | 1 |
| p.Asp36Tyr | p.Asp36Tyr | 1 | 1 |
| p.Gly140Ser | p.Gly140Ser | 1 | 1 |
| p.Arg284Ter | p.Arg284Ter | 1 | 1 |
| p.Pro106Leu | p.Pro106Leu | 1 | 1 |
| rs646218 | rs646218 | 1 | 1 |
| rs11053646 | rs11053646 | 1 | 1 |
| rs1105364 | rs1105364 | 1 | 1 |
| G20210A | G20210A | 1 | 1 |
| S188F | S188F | 1 | 1 |
| c.406C>T | c.406C>T | 1 | 1 |
| c.475C>T | c.475C>T | 1 | 1 |
| rs7069102 | rs7069102 | 1 | 1 |
| rs1801131 | rs1801131 | 1 | 1 |
| rs2910164 | rs2910164 | 1 | 1 |
| G52T | G52T | 1 | 1 |
| c.688_689insCG | c.688_689insCG | 1 | 1 |
| p.I27L | p.I27L | 1 | 1 |
| rs10757278 | rs10757278 | 1 | 1 |
| rs1333045 | rs1333045 | 1 | 1 |
| C806T | C806T | 1 | 1 |
| rs12255372 | rs12255372 | 1 | 1 |
| rs12248560 | rs12248560 | 1 | 1 |
| L12F | L12F | 1 | 1 |
| A56V | A56V | 1 | 1 |
| G75R | G75R | 1 | 1 |
| G87R | G87R | 1 | 1 |
| rs1045642 | rs1045642 | 1 | 1 |
| rs8192284 | rs8192284 | 1 | 1 |
| p.Asp358Ala | p.Asp358Ala | 1 | 1 |
| V617F | V617F | 1 | 1 |
| rs17576 | rs17576 | 1 | 1 |
| rs17156 | rs17156 | 1 | 1 |
| -174G>C | -174G>C | 1 | 1 |
| rs1128503 | rs1128503 | 1 | 1 |
| rs2032582 | rs2032582 | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026The Influence of Renal Function on Safety and Effectiveness of Oral Anticoagulant Treatment among Frail Elderly Patients with Non-Valvular Atrial Fibrillation and Chronic Kidney Disease.Cardiology1 mentions
- 2026Integrative transcriptomic and structural analysis identifies PTGS2 as a key target in ischemic stroke associated with neuroinflammation.Molecular diversity1 mentions
- 2026Genetic interleukin-6 receptor blockade, chronic disease risk, and longevity: results from the women's health initiative.European journal of preventive cardiology1 mentions
- 2026Horizontal semicircular canalith jam mimicking acute vestibular syndrome: physiotherapy-guided diagnosis and treatment in three cases.Physiotherapy theory and practice1 mentions
- 2026Functional and structural adaptations following immersive audiovisual training in post-stroke hemianopia: A study of behaviour, DTI, and FC.NeuroImage1 mentions
- 2026Surgical vs Transcatheter Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis- an Updated Meta-Analysis of Reconstructed Individual Patient Data.Interdisciplinary cardiovascular and thoracic surgery1 mentions
- 2026Prevalence of Ischemic Brain Injury in Neonates With Congenital Heart Disease: A Systematic Review and Meta-Analysis.Neurology1 mentions
- 2026Alien hand syndrome as the initial presentation of posterior cerebral artery infarction: a case report.BMC neurology1 mentions
- 2026Assessment of public knowledge and perception of stroke, seizures, and subarachnoid hemorrhage among adults aged ≥18 years in Saudi Arabia: A cross-sectional study.Medicine1 mentions
- 2026Impact of ileostomy creation on apixaban plasma concentrations: a retrospective case-series.Annals of Saudi medicine1 mentions
- 2026Reappraising cardiac function with myocardial contraction fraction: normal values, disease detection, and prognostication.European heart journal. Cardiovascular Imaging1 mentions
- 2026Prognostic Impact of New-Onset Atrial Fibrillation After Cardiac Arrest: Observations From a Federated Research Network.Journal of cardiovascular electrophysiology1 mentions
- 2026Short-term outcomes of pediatric HeartMate 3 left ventricular assist device: single center experience.ESC heart failure1 mentions
- 2026Beta-Blockers After Myocardial Infarction Without Reduced Ejection Fraction: A Meta-Analysis of Kaplan-Meier Reconstructed Individual Patient Data.American journal of cardiovascular drugs : drugs, devices, and other interventions1 mentions
- 2026Impact of cancer on outcomes following breakthrough ischaemic stroke on oral anticoagulants for atrial fibrillation: insights from the ASPERA-R study.European stroke journal1 mentions
- 2026Antiplatelet dilemma: Clopidogrel or aspirin for long-term cardiovascular protection after dual antiplatelet therapy following PCI.Medicine1 mentions
- 2026Long-term prognosis in Takotsubo syndrome compared to heart failure: observations from a global federated research network.ESC heart failure1 mentions
- 2026Unrepaired Truncus Arteriosus Type 1 With Eisenmenger Syndrome and Recurrent Embolic Strokes: An Adult Case Report.The American journal of case reports1 mentions
- 2026Sickle cell disease.Lancet (London, England)1 mentions
- 2026Single Nucleotide Polymorphisms in Stroke: Evidence Across Susceptibility, Prognosis, and Recurrence; A Systematic Review.Journal of molecular neuroscience : MN1 mentions
- 2026Complications in acute respiratory distress syndrome: a systematic review and meta-analysis.Critical care (London, England)1 mentions
- 2026Predictors of Critical Care Interventions and Length of Stay in Pediatric Sickle Cell Acute Chest Syndrome: A Five-Year Pediatric Intensive Care Unit (PICU) Cohort Study.Cureus1 mentions
- 2026Sex Differences in Outcomes After Breakthrough Ischemic Stroke on Oral Anticoagulants for Atrial Fibrillation: An ASPERA-R Inverse Probability Weighted Analysis.Journal of the American Heart Association1 mentions
- 2026Association of P2Y12 G52T genetic polymorphism with recurrent thromboembolic events in stroke and myocardial infarction patients on clopidogrel therapy: a prospective observational study.Scientific reports1 mentions
- 2026Neuropsychiatric Sequelae of COVID-19: A Systematic Review of Acute and Prolonged Effects.CNS & neurological disorders drug targets1 mentions
- 2026Unlocking the Mysteries: Stroke-like Episodes in Sturge-Weber Syndrome.Clinical medicine & research1 mentions
- 2026Exploring the Association of Genetic Determinants of SIRT1, MTHFR, and MIR146A Gene Polymorphism with the Ischemic Stroke Predisposition: A Case Control Study.Cellular and molecular neurobiology1 mentions
- 2026Competing Stroke Etiologies and Outcomes After Breakthrough Ischemic Stroke on Oral Anticoagulants in Patients With Atrial Fibrillation.Neurology1 mentions
- 2026Pulsed field ablation versus cryoballoon ablation for pulmonary vein isolation in atrial fibrillation: a systematic review and meta-analysis with subgroup analyses by AF type.BMC cardiovascular disorders1 mentions
- 2026Bacopa monnieri confers neuroprotection against middle cerebral artery occlusion (MCAO)-induced neurobehavioral and biochemical dysregulation in the frontal cortex and hippocampus of male Wistar rats.Journal of ethnopharmacology1 mentions
- 2026Prevalence of post-operative complications after craniotomy surgery, a tertiary hospital study, Saudi Arabia.Saudi journal of anaesthesia1 mentions
- 2026Albumin levels and risk of early cardiovascular complications after endovascular thrombectomy for acute ischaemic stroke.Scientific reports1 mentions
- 2026Predictors of Cerebrovascular Accident Among Sudanese Children with Sickle Cell Anemia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion1 mentions
- 2026Continuation vs Switching Direct Oral Anticoagulant Therapy After Breakthrough Stroke.JAMA network open1 mentions
- 2026Modulation of the serotonergic system restores oxidative balance and gene expression in the brain and heart of rats with obesity induced by overnutrition.Frontiers in physiology1 mentions
- 2026Targeting Neurovascular Pathways: Gene Therapy as a Novel Treatment for Vascular Dementia After Stroke.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2026Rare coding variation and stroke heterogeneity in Saudi Arabia: an exome‑wide association study across severity, etiology, vascular territory, and early‑onset disease.BMC neurology1 mentions
- 2026Impact of pre-operative factors on post-operative atrial fibrillation outcomes after cardiac surgery: systematic review with meta-analysis, trial sequential analysis, and meta-regression.Acta cardiologica1 mentions
- 2026Safety and efficacy of intravenous tenecteplase in patients with acute ischemic stroke in the extended time window: an updated meta-analysis.European journal of clinical pharmacology1 mentions
- 2026Internal carotid artery agenesis: A narrative review.Surgical neurology international1 mentions
- 2026The Incidence Rate of Post-Stroke Epilepsy: A Multi-Center, Retrospective Study in Taif City.Neurosciences (Riyadh, Saudi Arabia)1 mentions
- 2026Refractory XDR Klebsiella pneumoniae CAUTI Treated with non-antibiotic urinary acidification: a 12-month follow-up case report and literature review.Le infezioni in medicina1 mentions
- 2026Premature atherosclerotic cardiovascular disease in the MENA region: economic impact, barriers to care, and policy recommendations for an escalating crisis.Current opinion in lipidology1 mentions
- 2026Post-stroke epilepsy in Saudi Arabia - frequency, management and outcomes at a comprehensive stroke center in Riyadh, Kingdom of Saudi Arabia.BMC neurology1 mentions
- 2026CHIP In cardiovascular and immune ageing.Ageing research reviews1 mentions
- 2026New Insights into Genetic Polymorphisms Influencing the Therapeutic Efficacy and Toxicity of Rivaroxaban.Journal of clinical pharmacology1 mentions
- 2026Neurology and Cognitive Occupational Therapy Practice Across the Middle East and North Africa: An Exploratory Multicountry Cross-Sectional Survey.Occupational therapy international1 mentions
- 2026Mechanical Thrombectomy as Stroke Management in Pregnancy: A Systematic Review.Stroke (Hoboken, N.J.)1 mentions
- 2026Cerebrovascular and Bleeding Outcomes of Warfarin versus Direct Oral Anticoagulants Therapy for Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Neurosciences (Riyadh, Saudi Arabia)1 mentions
- 2026Latent Class Analysis to Identify Phenotype-Specific Treatment Effects of Catheter Ablation Versus Drug Therapy in Patients with Atrial Fibrillation: A Secondary Analysis of the CABANA Trial.Heart rhythm1 mentions
- 2026Exploring Parakinesia Brachialis Oscitans: An Intriguing Post-Stroke Phenomenon.Clinical medicine & research1 mentions
- 2026Splenectomy Impact and Outcome Among Patients With Sickle Cell Disease: A Cross-Sectional Study.Health science reports1 mentions
- 2026Standardized endpoint definitions for trials of transcatheter left atrial appendage closure: a consensus from the Left Atrial Appendage Academic Research Consortium†.European heart journal1 mentions
- 2025Left Atrial Appendage Occlusion versus Direct Oral Anticoagulants in the Prevention of Ischaemic Stroke in Patients with Atrial Fibrillation.Cerebrovascular diseases (Basel, Switzerland)1 mentions
- 2025Clinical Implications of Various Electroencephalographic Patterns in Post-Stroke Seizures. The Utility of Routine Electroencephalogram.Clinical EEG and neuroscience1 mentions
- 2025Choice of revascularization strategy for ischemic cardiomyopathy due to multivessel coronary disease.The Journal of thoracic and cardiovascular surgery1 mentions
- 2025Relationships Between APOE, Type 2 Diabetes, and Cardiovascular Disease in Postmenopausal Women.The journals of gerontology. Series A, Biological sciences and medical sciences1 mentions
- 2025Clinical and Radiological Parameters Affecting the Yield of Routine Electroencephalography in Various Indications.Annals of African medicine1 mentions
- 2025Depression unveiled: Insights into etiology and animal models for behavioral assessment, exploring the multifactorial nature and treatment of depression.Brain research1 mentions
- 2025Dentistry and Sturge-Weber syndrome: Case report and narrative review.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry1 mentions
- 2025Use of antithrombotic therapy in patients with hemophilia: a selected synopsis of the European Hematology Association - International Society on Thrombosis and Haemostasis - European Association for Hemophilia and Allied Disorders - European Stroke Organization Clinical Practice Guidance document.Journal of thrombosis and haemostasis : JTH1 mentions
- 2025High penetrance and phenotypic landscape of methylenetetrahydrofolate reductase c.665 C>T polymorphism in the absence of folate fortification.Clinical nutrition ESPEN1 mentions
- 2025Effects of Physiotherapy Interventions for Poststroke Fatigue: A Systematic Review.Stroke1 mentions
- 2025The impact of new-onset atrial fibrillation in the setting of acute coronary syndrome.Journal of cardiology1 mentions
- 2025Overweight, obesity, and cardiovascular disease in heterozygous familial hypercholesterolaemia: the EAS FH Studies Collaboration registry.European heart journal1 mentions
- 2025Clinical Outcomes with High- versus Low-Dose Tranexamic Acid Infusion in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis.The Thoracic and cardiovascular surgeon1 mentions
- 2025The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology1 mentions
- 2025Indications for Blood Transfusion and Exchange Transfusion in Sickle Cell Disease: A Single Center Experience.Cureus1 mentions
- 2025Prevalence of bleeding in patients on single or dual antiplatelet therapy combined with vitamin K antagonists or direct oral anticoagulants.The International journal of risk & safety in medicine1 mentions
- 2025Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review.Frontiers in pharmacology1 mentions
- 2025The Direct Medical Costs of Sickle Cell Disease in Saudi Arabia: Insights from a Single Center Study.Healthcare (Basel, Switzerland)1 mentions
- 2025A multicenter analysis to identify the risk factors for stroke recurrence and mortality within 1 year.Frontiers in neurology1 mentions
- 2025Whole genome transcriptomic profiling reveals distinct sex-specific responses to heat stroke.Journal of applied physiology (Bethesda, Md. : 1985)1 mentions
- 2025Plasma Atrial Natriuretic Peptide Predicts Oxidized Low-Density Lipoprotein Levels in Type 2 Diabetes Mellitus Patients Independent of Circulating Adipokine and Cytokine.International journal of molecular sciences1 mentions
- 2025Nano-healing: Exploring the Therapeutic Potentials of Nanomedicine for CNS Disorders.Current pharmaceutical design1 mentions
- 2025The role of VEGF in vascular dementia: impact of aging and cellular senescence.Biogerontology1 mentions
- 2025A 65-Year-Old Man with Coronary Artery Embolism and Acute Inferior Myocardial Infarction Following Cardioversion for Ventricular Tachycardia.The American journal of case reports1 mentions
- 2025Risk factors, clinical characteristics, and outcomes of perinatal stroke in a Tertiary University Hospital.Neurosciences (Riyadh, Saudi Arabia)1 mentions
- 2025Deep learning for cerebral vascular occlusion segmentation: A novel ConvNeXtV2 and GRN-integrated U-Net framework for diffusion-weighted imaging.Neuroscience1 mentions
- 2025Systematic Review of Prehospital Prediction Models for Identifying Intracerebral Haemorrhage in Suspected Stroke Patients.Healthcare (Basel, Switzerland)1 mentions
- 2025A multi-center study on the predictors of different subtypes of hemorrhagic transformation of brain infarction after thrombolysis in atrial fibrillation patients presented with embolic stroke.Scientific reports1 mentions
- 2025Impact of Central Event Adjudication on the PLATO Trial Results.Reviews in cardiovascular medicine1 mentions
- 2025Pattern of anticoagulation prescription for elderly atrial fibrillation patients with or without severe dementia: A retrospective analysis of patient data.Medicine1 mentions
- 2025Colorimetric loop-mediated isothermal amplification (cLAMP) assay for the genotyping of a thrombophilia genetic risk factor, MTHFR (C677T).Analytical methods : advancing methods and applications1 mentions
- 2025Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021.JAMA neurology1 mentions
- 2025Position Paper on the Management of Sickle Cell Disease in Saudi Arabia: Understanding Disease Landscape, Identifying Challenges, and Exploring Opportunities in Transfusion Therapies.Journal of clinical medicine1 mentions
- 2025Causal assessment of the relationship between diet, lifestyle, and stroke: A two-sample Mendelian randomization study.Medicine1 mentions
- 2025Deep convolutional fuzzy neural networks with stork optimization on chronic cardiovascular disease monitoring for pervasive healthcare services.Scientific reports1 mentions
- 2025Evaluation of gaps in direct oral anticoagulants (DOACs) management in an outpatient underserved clinic: a cross-sectional study.Scientific reports1 mentions
- 2025Impact of ventricular arrhythmias on patients with spontaneous coronary artery dissection: a systematic review and meta-analysis.Panminerva medica1 mentions
- 2025Platelet reactivity to adenosine diphosphate and CYP2C19 genotypes are linked with carotid plaques and may predict carotid plaque stability in acute ischemic stroke patients.Neurosciences (Riyadh, Saudi Arabia)1 mentions
- 2025Computational prediction of the pathogenic variants of arachidonate 5-lipoxygenase activating protein using Molecular Dynamics simulation.PloS one1 mentions
- 2025Precision in Practice: Clinical Indication-Specific DRLs for Head CT for Advanced Personalised Dose Benchmarking.Diagnostics (Basel, Switzerland)1 mentions
- 2025Haplo-stem cell transplant post liver transplantation to cure sickle cell disease with related liver dysfunction: a case series.Communications medicine1 mentions
- 2025Cerebral venous thrombosis: A comprehensive narrative review.Brain circulation1 mentions
- 2025Evaluation of the Clinical Outcomes of Apixaban Use in Patients with Atrial Fibrillation and Uncontrolled Hypothyroidism: A Real-world Evidence.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis1 mentions
- 2025Impact of vascular risk factors on endovascular mechanical thrombectomy outcomes in patients with stroke.Biomedical reports1 mentions
- 2025Pharmacological landscape of linarin: From benchside mechanisms to potential bedside applications.Fitoterapia1 mentions
- 2025Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023.Journal of the American College of Cardiology1 mentions
- 2025Advanced supervised machine learning methods for precise diabetes mellitus prediction using feature selection.Frontiers in medicine1 mentions