inflammatory bowel disease
SaudiVarKB evidence summary derived from retained literature mentions.
691Phenotype mentions
100Publications
50Associated gene records
34Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| TLR4 | HGNC:11850 | 10 | 10 |
| STAT3 | HGNC:11364 | 7 | 7 |
| NLRP3 | HGNC:16400 | 6 | 6 |
| SIRT1 | HGNC:14929 | 5 | 5 |
| RIPK1 | HGNC:10019 | 4 | 4 |
| NOD2 | HGNC:5331 | 4 | 4 |
| HMGB1 | HGNC:4983 | 4 | 4 |
| MPO | HGNC:7218 | 3 | 3 |
| IL10 | HGNC:5962 | 3 | 3 |
| EGFR | HGNC:3236 | 3 | 3 |
| BAX | HGNC:959 | 3 | 3 |
| TYK2 | HGNC:12440 | 2 | 2 |
| BCL2 | HGNC:990 | 2 | 2 |
| CARMIL2 | HGNC:27089 | 2 | 2 |
| LRRK2 | HGNC:18618 | 2 | 2 |
| ABCB1 | HGNC:40 | 2 | 2 |
| LDLR | HGNC:6547 | 2 | 2 |
| JAK2 | HGNC:6192 | 2 | 2 |
| CD44 | HGNC:1681 | 2 | 2 |
| CD28 | HGNC:1653 | 2 | 2 |
| NCF2 | HGNC:7661 | 2 | 2 |
| CD200R1 | HGNC:24235 | 2 | 2 |
| TPMT | HGNC:12014 | 2 | 2 |
| TFAM | HGNC:11741 | 2 | 2 |
| MUC2 | HGNC:7512 | 2 | 2 |
| DLG5 | HGNC:2904 | 2 | 2 |
| CPT1A | HGNC:2328 | 1 | 1 |
| PAH | HGNC:8582 | 1 | 1 |
| COL1A1 | HGNC:2197 | 1 | 1 |
| TNF | HGNC:11892 | 1 | 1 |
| APOE | HGNC:613 | 1 | 1 |
| ATF6 | HGNC:791 | 1 | 1 |
| VWF | HGNC:12726 | 1 | 1 |
| CD40 | HGNC:11919 | 1 | 1 |
| TBX4 | HGNC:11603 | 1 | 1 |
| G6PD | HGNC:4057 | 1 | 1 |
| CFTR | HGNC:1884 | 1 | 1 |
| CAST | HGNC:1515 | 1 | 1 |
| CRP | HGNC:2367 | 1 | 1 |
| SQSTM1 | HGNC:11280 | 1 | 1 |
| AGL | HGNC:321 | 1 | 1 |
| CYP3A4 | HGNC:2637 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| CXCL8 | HGNC:6025 | 1 | 1 |
| AKT1 | HGNC:391 | 1 | 1 |
| MALAT1 | HGNC:29665 | 1 | 1 |
| S100A9 | HGNC:10499 | 1 | 1 |
| IMPACT | HGNC:20387 | 1 | 1 |
| TF | HGNC:11740 | 1 | 1 |
| VDR | HGNC:12679 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| Q53L | Q53L | 1 | 1 |
| Y99N | Y99N | 1 | 1 |
| W351G | W351G | 1 | 1 |
| D365A | D365A | 1 | 1 |
| Q376H | Q376H | 1 | 1 |
| V25I | V25I | 1 | 1 |
| W100G | W100G | 1 | 1 |
| rs6505162 | rs6505162 | 1 | 1 |
| rs7975232 | rs7975232 | 1 | 1 |
| rs1544410 | rs1544410 | 1 | 1 |
| rs731236 | rs731236 | 1 | 1 |
| p.W577C | p.W577C | 1 | 1 |
| G894T | G894T | 1 | 1 |
| rs2228570 | rs2228570 | 1 | 1 |
| C1672T | C1672T | 1 | 1 |
| G113A | G113A | 1 | 1 |
| C4136A | C4136A | 1 | 1 |
| rs1799964 | rs1799964 | 1 | 1 |
| rs1050152 | rs1050152 | 1 | 1 |
| G58V | G58V | 1 | 1 |
| G313V | G313V | 1 | 1 |
| c.855_856del | c.855_856del | 1 | 1 |
| rs992157 | rs992157 | 1 | 1 |
| rs2382817 | rs2382817 | 1 | 1 |
| C3435T | C3435T | 1 | 1 |
| rs3810936 | rs3810936 | 1 | 1 |
| rs7848647 | rs7848647 | 1 | 1 |
| rs6478108 | rs6478108 | 1 | 1 |
| W69G | W69G | 1 | 1 |
| p.T84I | p.T84I | 1 | 1 |
| p.Y91C | p.Y91C | 1 | 1 |
| p.R101W | p.R101W | 1 | 1 |
| p.R117C | p.R117C | 1 | 1 |
| p.R117H | p.R117H | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026AQP9 and IFITM1 as drivers of immune infiltration and tumor progression in IBD-associated colorectal cancer: from computational insights to experimental validation.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Ultraprocessed Grains and Risk of Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology Study.The American journal of gastroenterology1 mentions
- 2026A Review on Functional Foods Regulate the Gut Microbiota and Mast Cell Function in Inflammatory Bowel Disease (IBD).Probiotics and antimicrobial proteins1 mentions
- 2026Frequency of thiopurine methyltransferase variants and exploratory predictors of azathioprine-induced leukopenia in Saudi patients with inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Cost calculation model of introducing Upadacitinib and Risankizumab for adult ulcerative colitis and Crohn's disease in the Kingdom of Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Patterns and predictors of biologic therapy switching in inflammatory bowel disease at a tertiary care center: A retrospective observational study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026The Impact of Disease Activity and Medications on Pregnancy and Fetal Outcomes in Women With Inflammatory Bowel Disease: A Cohort Study From the IBD-ME Group.Journal of gastroenterology and hepatology1 mentions
- 2026Evaluation of 1H-pyrazol-1-yl benzenesulfonamide derivatives in alleviating inflammatory bowel disease via PI3K/Akt/mTOR signaling pathway in zebrafish models.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity1 mentions
- 2026The melatonin-microbiome axis: a new frontier in gut health for the immunomodulatory, antioxidant and anti-inflammatory properties.Inflammopharmacology1 mentions
- 2026Practical guidelines on medical management of adults with moderate-to-severe inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Unlocking potentials of a prenylated flavonoid: Xanthohumol's role in combating inflammatory conditions and Rhematic diseases.Cytokine1 mentions
- 2026Protective Effects of Herbacetin in Experimental Colitis: Targeting NF-κB and NLRP3 Pathways.Drug development research1 mentions
- 2026Modulation of Inflammatory and Apoptotic Pathways by Tamarix Aphylla Essential Oil in TNBS-Induced Colitis: A Focus on Cytokine Balancing, NF-κB, p38 MAPK, and Nrf2 Activation.Applied biochemistry and biotechnology1 mentions
- 2026Effectiveness and safety of upadacitinib in refractory pediatric inflammatory bowel disease: A single-arm meta-analysis of observational studies.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026The efficacy of adipose-derived stem cell therapy for complex perianal fistulas in Crohn's disease patients: A systematic review.Surgery open science1 mentions
- 2026A Mangifera indica L. extract functions as a broad TLR2/4/6 signalling rheostat to attenuate MyD88/NF-κB-driven inflammation and macrophage polarization.Pharmacological research1 mentions
- 2026Digital horizons: Exploring the future of AI-enabled gastroenterology in the Kingdom of Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Investigating therapeutic efficacy of Lactobacillus salivarius GZLC1 on colitis by examining its effects on intestinal fungi, antioxidant capacity, and inflammatory response in mice.Beneficial microbes1 mentions
- 2026Co-Occurrence of Inflammatory Bowel Disease in Patients with Vitiligo: A Systematic Review and Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology1 mentions
- 2026Association between spicy food consumption and inflammatory bowel disease: A case-control study from Saudi Arabia.Nutrition (Burbank, Los Angeles County, Calif.)1 mentions
- 2026Liposomal amphotericin B in the treatment of pediatric gastrointestinal basidiobolomycosis.Journal of medical case reports1 mentions
- 2026Optimizing vedolizumab therapy in ulcerative colitis: A critical synthesis of trial evidence and the emerging role of artificial intelligence.PLOS digital health1 mentions
- 2026Redrawing the gut map: evolving probiotic approaches to microbiota modulation in inflammatory bowel disease.Antonie van Leeuwenhoek1 mentions
- 2026Advanced therapies for inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and meta-analysis.Inflammatory bowel diseases1 mentions
- 2026Prevalence and Clinical Correlates of Fibromyalgia Screening Positivity in Patients with Inflammatory Bowel Disease.Journal of clinical medicine1 mentions
- 2026Diagnostic challenges and treatment approaches for Clostridioides difficile infection in IBD patients.Frontiers in microbiology1 mentions
- 2026Repurposing alogliptin for ulcerative colitis: involvement of MicroRNAs, anti-inflammatory, and barrier-restoring mechanisms.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Confocal Laser Endomicroscopy: Real-Time Histology at the Fingertips: A Comprehensive Review of Current Applications of Endomicroscopy in Barrett Esophagus, Inflammatory Bowel Disease, and Colorectal Lesions.Medicina (Kaunas, Lithuania)1 mentions
- 2026Ulcerative colitis, pathophysiological mechanisms and drug repurposing: a new therapeutic dawn-narrative review.Inflammopharmacology1 mentions
- 2026Mirikizumab four-year sustained and durable efficacy and safety in ulcerative colitis: Final findings from the LUCENT-3 open-label extension study.Inflammatory bowel diseases1 mentions
- 2026Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis.Inflammatory bowel diseases1 mentions
- 2026Association Between Ultraprocessed Food Intake and Inflammatory Bowel Disease Risk: A Propensity-Matched Analysis With Monte Carlo Simulation From the Prospective Urban Rural Epidemiology Study.Gastroenterology1 mentions
- 2026Accelerated Muscle Strength Decline and Reduced Lean Mass in Adults with Treated Inflammatory Bowel Disease: A NHANES Study.Journal of lifestyle medicine1 mentions
- 2026Comparing the pharmacokinetics of adalimumab originator and biosimilar product in patients with Inflammatory bowel disease or autoimmune disease.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2026Immunoinformatic-based design of a multi-epitope subunit vaccine against Ruminococcus torques using subtractive proteomics and molecular dynamics simulations.Scientific reports1 mentions
- 2026Characteristics, Complications, Comorbidities, and Other Manifestations of Inflammatory Bowel Disease: A 7-Year Tertiary Center Experience.Clinics and practice1 mentions
- 2026STING pathway contributes to Steroid-Hyporesponsive Lung Inflammation in DSS-induced colitis mice model.PloS one1 mentions
- 2026Clinical consequences of delayed recognition of gastrointestinal basidiobolomycosis: a case series.Journal of surgical case reports1 mentions
- 2026Colon-targeted pH-responsive tofacitinib beads improve ulcerative colitis outcomes with lower systemic exposure.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2026Bacterial and fungal biomarkers in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD): trans-kingdom interactions, Blastocystis carriage, and enterotype-succinotype stratification.Gut pathogens1 mentions
- 2026Harnessing Nanocarriers to Modulate Gut Inflammation: A New Era in IBD Management.Recent advances in inflammation & allergy drug discovery1 mentions
- 2026Marine algal TNF-α inhibitors explored by comparative docking and molecular dynamics simulations.Computational biology and chemistry1 mentions
- 2026Correction: A Cross-Sectional Study on Pediatric Resident Knowledge and Perceptions of Irritable Bowel Syndrome and Inflammatory Bowel Disease in Western Saudi Arabia.Cureus1 mentions
- 2026Self-Management Interventions in Young Adults (18-30 Years) With Type 1 Diabetes, Sickle Cell Disease, and Inflammatory Bowel Disease: A Scoping Review.Chronic diseases and translational medicine1 mentions
- 2026Mode of birth and risk of inflammatory bowel disease in offspring: an updated systematic review and meta-analysis.Frontiers in reproductive health1 mentions
- 2026Medicinal Plants and the Gastrointestinal Microbiota in Chronic Diseases Modulation: A Structured Mechanistic and Translational Review.Current microbiology1 mentions
- 2026Epigenetic Alterations in Microbiome-Host Interactions in Inflammatory and Autoimmune Diseases.International journal of molecular sciences1 mentions
- 2026Prevalence of Fatigue Among Inflammatory Bowel Disease Patients at a Tertiary Center in Saudi Arabia.Journal of clinical medicine1 mentions
- 2026Adjunctive Pentoxifylline Enhances Clinical Remission and Reduces Inflammatory Biomarkers in Mild-to-Moderate Ulcerative Colitis: A Randomized Double-Blind Placebo-Controlled Pilot Trial.Pharmaceuticals (Basel, Switzerland)1 mentions
- 2026Toward a United Arab Emirates national inflammatory bowel disease transition care pathway: Findings from a healthcare professional survey and development of evidence-based tools.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Silver nanoparticle-conjugated pyrimidine-based BN6 methanimine derivative improves DSS-induced inflammatory bowel disease in zebrafish.Immunopharmacology and immunotoxicology1 mentions
- 2026HOCl-Mediated Bromothymol Blue Bleaching and Carbon Dot Fluorescence Recovery for Fecal Myeloperoxidase Quantification in Ulcerative Colitis.Journal of fluorescence1 mentions
- 2026Combined acylated catalpol diglycoside and Lactobacillus therapy restores the miR-146a-TRAF6-SIRT1/AMPK signaling axis in experimental colitis.Toxicology and applied pharmacology1 mentions
- 2026A Review of Curcumin in Chronic Disease Management: Anti-Inflammatory Pathways, Antioxidant Activity, and Therapeutic Advances.Journal of nutrition and metabolism1 mentions
- 2026Prevalence, patient characteristics, and outcomes of high-dose upadacitinib in inflammatory bowel disease.Therapeutic advances in gastroenterology1 mentions
- 2026Oxidative Stress-Gut Microbiome Crosstalk: Intestinal Redox Imbalance and Probiotics Therapeutic Potential.Antioxidants (Basel, Switzerland)1 mentions
- 2026Medication Use and Guideline Adherence in Inflammatory Bowel Disease Management: A Retrospective Study from a Tertiary Care Hospital in Pakistan (2019-2024).International journal of general medicine1 mentions
- 2026Erratum to "The Association between Inflammatory Bowel Disease and Ischemic Heart Disease: A Retrospective Cohort Study" [Saudi Medical Journal 2025 Oct; 46(10):1174-1181].Saudi medical journal1 mentions
- 2026Fatigue in inflammatory bowel disease: Mechanisms, assessment, and management strategies.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Discordance between observer and patient-reported shared decision-making in inflammatory bowel disease: A multicenter cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Prevalence and etiology of abnormal liver function tests in a tertiary inflammatory bowel disease cohort in the United Arab Emirates: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026STRIDE-II treatment target achievement in inflammatory bowel disease: a cross-sectional study from a tertiary IBD centre in the United Arab Emirates.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Orbital manifestations of inflammatory bowel disease - a systematic review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie1 mentions
- 2026Global phenotypic similarity in inflammatory bowel disease: the Eastern Mediterranean region perspective.Journal of Crohn's & colitis1 mentions
- 2026Mucin armoured diethylaminoethyl-dextran cloaked rebamipide based oral nanoformulation for the therapy of inflammatory bowel disease.Materials today. Bio1 mentions
- 2026Association between residential greenness and the risk of inflammatory bowel disease in patients with COVID-19: A Korean nationwide cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Disease burden of inflammatory bowel disease and subtypes in older adults in 172 high- and middle-income countries: Trends from 2000 to 2023 and projections to 2040.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Non-Invasive Multimarker Strategy Combining IL-17A, Neutrophil-Albumin Ratio, and Fecal Calprotectin for Accurate Discrimination of IBD from IBS-D.International journal of molecular sciences1 mentions
- 2026Adherent-Invasive Escherichia coli (AIEC) in Crohn's Disease: A Bibliometric Analysis of 25 Years of Research (1999-2025).Microorganisms1 mentions
- 2026Patient Preferences for Virtual Versus In-Person Care in Inflammatory Bowel Disease: A Cross-Sectional Study.Telemedicine journal and e-health : the official journal of the American Telemedicine Association1 mentions
- 2026The relationship of apical periodontitis with chronic diseases and smoking habits: an umbrella review.Odontology1 mentions
- 2026Short, not skinny: The distinct sarcopenia phenotype of pediatric primary sclerosing cholangitis-inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition1 mentions
- 2026Patient preferences toward the attributes of treatment used for inflammatory bowel disease in Saudi Arabia: Subgroup analysis from an international multicenter discrete choice experiment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Ustekinumab Drug Levels and Outcomes in Inflammatory Bowel Disease.Journal of clinical gastroenterology1 mentions
- 2025Rates, Predictors, and Outcomes of Ustekinumab Dose Escalation in Inflammatory Bowel Disease.Journal of clinical gastroenterology1 mentions
- 2025Clinical effectiveness and safety of ustekinumab in youth with refractory inflammatory bowel disease: A retrospective cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecular mechanisms.Critical reviews in microbiology1 mentions
- 2025Bacterial metabolomics: current applications for human welfare and future aspects.Journal of Asian natural products research1 mentions
- 2025Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025The effectiveness of vedolizumab in advanced therapy-experienced ulcerative colitis patients: Real world data from the Inflammatory Bowel Disease of the Middle East (IBD-ME) Registry group.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Histone Deacetylases (HDACs) Roles in Inflammation-mediated Diseases; Current Knowledge.Cell biochemistry and biophysics1 mentions
- 2025Corrigendum to "pH-Sensitive Tacrolimus loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease" [Eur. J. Pharm. Biopharm. 204 (2024) 114461].European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V1 mentions
- 2025Editorial: The safety and efficacy of ustekinumab in anti-TNF α refractory pediatric inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025A bibliometric analysis of inflammatory bowel disease research in the Arab world.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Coexisting autoimmune disorders among patients with inflammatory bowel disease at a tertiary center in Saudi Arabia: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Outcomes of Hematopoietic Stem Cell Transplantation in 5 Patients with Autosomal Recessive RIPK1-Deficiency.Journal of clinical immunology1 mentions
- 2025Hepatobiliary manifestations of inflammatory bowel disease in Saudi Arabia: A retrospective analysis.Saudi medical journal1 mentions
- 2025Effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis.Therapeutic advances in gastroenterology1 mentions
- 2025A review on the effects of flavan-3-ols, their metabolites, and their dietary sources on gut barrier integrity.Food & function1 mentions
- 2025Prevalence and clinical implications of anti-drug antibody formation and serum drug levels among patients with IBD receiving anti-TNF therapy: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Nutraceutical Impact of Pumpkin Seed Oil on Expression Levels of EZH-2 and KRT-14 Genes against DSS-induced Inflammatory Bowel Disease in the Rat Model.Cell biochemistry and biophysics1 mentions
- 2025Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres.Drugs in context1 mentions
- 2025Dichotomous effects of Galectin-9 in disease modulation in murine models of inflammatory bowel disease.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie1 mentions
- 2025Dihydroartemisinin attenuates acetic acid-induced ulcerative colitis in rats: Suppression of inflammation and modulation of NFκβ/TNF-α/RIPK1-mediated necroptosis and apoptosis.Tissue & cell1 mentions
- 2025Colorectal Neoplasia in Inflammatory Bowel Disease.Cancers1 mentions
- 2025High-Throughput Whole-Exome Sequencing and Large-Scale Computational Analysis to Identify the Genetic Biomarkers to Predict the Vedolizumab Response Status in Inflammatory Bowel Disease Patients from Saudi Arabia.Biomedicines1 mentions
- 2025Chloride channels and mast cell function: pioneering new frontiers in IBD therapy.Molecular and cellular biochemistry1 mentions
- 2025Inulin Protects Caco-2 Cells Against Lipopolysaccharide-Induced Epithelial Barrier Dysfunction.Food science & nutrition1 mentions
- 2025Authors' comment on: effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis.Therapeutic advances in gastroenterology1 mentions