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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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Phenotype
COVID-19
1,317articles
1,317mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
2 records shown · first 60Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants.
PMID 35215242 | PMCID PMC8877620 | DOI 10.3390/ph15020129 · Pharmaceuticals (Basel, Switzerland) · 2022 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | COVID-19 | “Fighting against the emergent coronavirus disease (COVID-19) remains a big challenge at the front of the world communities.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs961360700 | “The best score was recorded with rs961360700.” | 0.90 | hgvs_regex_v1 |
| gene | ACE2 | “Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants.” | 0.98 | hgnc_dict_v1 |
| phenotype | SARS | “To assess their potential use against COVID-19, the interactions of the main active principle of Artemisia with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) was investigated through in silico probing.” | 0.93 | phenotype_alias_lexicon_v2 |
Receptor binding domain of SARS-CoV-2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2.
PMID 35738053 | PMCID PMC9212875 | DOI 10.1016/j.jiph.2022.06.004 · Journal of infection and public health · 2022 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | COVID-19 | “BACKGROUND: COVID-19 is an infectious disease declared as a global pandemic caused by SARS-CoV-2 virus.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs961360700 | “The ACE2 with rs961360700 variant showed the least binding energy (-895.2 Kcal/mol) on binding with the RBD of Phe160Ser variant compared to Wuhan's RBD complex.” | 0.90 | hgvs_regex_v1 |
| gene | ACE2 | “Receptor binding domain of SARS-CoV-2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2.” | 0.98 | hgnc_dict_v1 |