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Phenotype
HIV infection
146articles
146mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.
PMID 38451012 | PMCID PMC10955225 | DOI 10.1002/mgg3.2362 · Molecular genetics & genomic medicine · 2024 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | HIV infection | “Moreover, when comparing HIV patients with hepatotoxicity to healthy controls, the haplotype GA had an association with an elevated risk for the development of hepatotoxicity (p = 0.041, OR = 1.73, 95% CI: 1.02-2.93).” | 0.93 | phenotype_alias_lexicon_v2 |
| variant | rs2231137 | “METHODS: To investigate this, we examined ABCG2 34G/A (rs2231137) and 421C/A (rs2231142) genetic variations in 149 HIV-infected patients (116 without hepatotoxicity, 33 with ARV-induced hepatotoxicity) and 151 healthy controls through the PCR-restriction fragment length polymorphism (PCR-RFLP) technique.” | 0.90 | hgvs_regex_v1 |
| gene | ABCG2 | “ABCG2 polymorphisms and susceptibility to ARV-associated hepatotoxicity.” | 0.98 | hgnc_dict_v1 |
| variant | rs2231142 | “METHODS: To investigate this, we examined ABCG2 34G/A (rs2231137) and 421C/A (rs2231142) genetic variations in 149 HIV-infected patients (116 without hepatotoxicity, 33 with ARV-induced hepatotoxicity) and 151 healthy controls through the PCR-restriction fragment length polymorphism (PCR-RFLP) technique.” | 0.90 | hgvs_regex_v1 |