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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
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Phenotype
MERS
230articles
230mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach.
PMID 34346317 | PMCID PMC8282961 | DOI 10.1016/j.compbiomed.2021.104654 · Computers in biology and medicine · 2021 · 16 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | MERS | “The spreading rate of SARS-CoV-2 is higher than MERS-CoV and SARS-CoV.” | 0.93 | phenotype_alias_lexicon_v2 |
| variant | A845V | “Using the extensive bioinformatics pipeline, we screened the destabilizing (L8V, L8W, L18F, Y145H, M153T, F157S, G476S, L611F, A879S, C1247F, and C1254F) and stabilizing (H49Y, S50L, N501Y, D614G, A845V, and P1143L) nonsynonymous mutations in the S-protein.” | 0.82 | literature_variant_regex_v2 |
| gene | ACE2 | “Investigation of nonsynonymous mutations in the spike protein of SARS-CoV-2 and its interaction with the ACE2 receptor by molecular docking and MM/GBSA approach.” | 0.98 | hgnc_dict_v1 |
| phenotype | COVID-19 | “COVID-19 is an infectious and pathogenic viral disease caused by SARS-CoV-2 that leads to septic shock, coagulation dysfunction, and acute respiratory distress syndrome.” | 0.98 | phenotype_alias_lexicon_v2 |