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Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
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Phenotype
Parkinson disease
280articles
280mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Redox modulatory role of DJ-1 in Parkinson's disease.
PMID 40159591 | DOI 10.1007/s10522-025-10227-w · Biogerontology · 2025 · 3 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | Parkinson disease | “Redox modulatory role of DJ-1 in Parkinson's disease.” | 0.93 | phenotype_alias_lexicon_v2 |
| variant | L166P | “It has been demonstrated that DJ-1 functions as an oxidative stress sensor, and mutations like L166P cause loss of antioxidant activity and increased Reactive Oxygen Species (ROS) accumulation with subsequent mitochondrial dysfunction in dopaminergic neurons.” | 0.82 | literature_variant_regex_v2 |
| gene | PARK7 | “DJ-1 (PARK7) is a key factor for maintaining redox homeostasis and modulation of mitochondrial function to preserve the cellular survival pathways.” | 0.98 | hgnc_dict_v1 |