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Phenotype
Malaria
232articles
232mentions
12co-reported genes shown
Most co-reported genes (articles)
Counts are literature co-mentions in SaudiVarKB, not clinical or causal assertions. Gene details: HGNC; variant status: ClinVar via dbSNP.
Publications
1 records shown · first 60Association between interleukin-27 gene polymorphisms and Plasmodium falciparum Malaria.
PMID 37306242 | PMCID PMC10357889 | DOI 10.1177/17534259231178594 · Innate immunity · 2023 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | malaria | “Association between interleukin-27 gene polymorphisms and Plasmodium falciparum Malaria.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs181206 | “The minor allele C of variant rs181206 exhibited an association with low to moderate parasitemia (P = 0.046).” | 0.90 | hgvs_regex_v1 |
| population | Saudi Arabia, Jazan | “This study aimed to investigate the role of interleukin-27 (IL-27) gene polymorphisms in Plasmodium falciparum malaria infection in a Saudi Arabian cohort. This case-control study obtained blood samples from 250 malaria patients with P. falciparum and 200 randomly identified healthy control subjects from the Malaria Center in the Jazan area.” | 0.95 | saudi_context_rules_v1 |
| variant | rs181209 | “The results show that the IL-27 variant rs181209 was significantly associated with malaria patients (P = 0.026).” | 0.90 | hgvs_regex_v1 |