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1 records shown · first 60Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension.
PMID 39492848 | PMCID PMC11531276 | DOI 10.2147/PGPM.S481068 · Pharmacogenomics and personalized medicine · 2024 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs2239050 | “RESULTS: Notable association were observed between SNP rs2239050/CACNA1C and amlodipine blood pressure response, with GG genotype carriers demonstrating a better response (P=0.004) than individuals carrying CC or CG genotypes.” | 0.90 | hgvs_regex_v1 |
| gene | CACNA1C | “This study investigated the correlation between single nucleotide polymorphisms (SNPs) in selected genes (CACNA1C, CACNA1D, ABCB1, ACE, ADBR2, and NOS1AP) and the blood pressure (BP) control by amlodipine.” | 0.98 | hgnc_dict_v1 |
| gene | CACNA1D | “This study investigated the correlation between single nucleotide polymorphisms (SNPs) in selected genes (CACNA1C, CACNA1D, ABCB1, ACE, ADBR2, and NOS1AP) and the blood pressure (BP) control by amlodipine.” | 0.98 | hgnc_dict_v1 |
| gene | ABCB1 | “This study investigated the correlation between single nucleotide polymorphisms (SNPs) in selected genes (CACNA1C, CACNA1D, ABCB1, ACE, ADBR2, and NOS1AP) and the blood pressure (BP) control by amlodipine.” | 0.98 | hgnc_dict_v1 |