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Polymorphisms in RAD51 and their relation with breast cancer in Saudi females.

PMID 26834486 | PMCID PMC4716748 | DOI 10.2147/OTT.S93343 · OncoTargets and therapy · 2016 · 7 validated mentions
TypeEntitySource evidenceConfidenceExtractor
variantrs2619681“The present study aimed at investigating the relationship between rs1801320 (G>C), rs1801321 (G>T), and rs2619681 (C>T) RAD51 gene polymorphisms and the risk of breast cancer development in Saudi females.”0.90hgvs_regex_v1
geneRAD51“Polymorphisms in RAD51 and their relation with breast cancer in Saudi females.”0.98hgnc_dict_v1
phenotypebreast cancer“Polymorphisms in RAD51 and their relation with breast cancer in Saudi females.”0.98phenotype_alias_lexicon_v2
populationSaudi Arabia“Polymorphisms in RAD51 and their relation with breast cancer in Saudi females. The present study aimed at investigating the relationship between rs1801320 (G>C), rs1801321 (G>T), and rs2619681 (C>T) RAD51 gene polymorphisms and the risk of breast cancer development in Saudi females. In the Saudi females, rs1801320 did not show an association with risk of breast cancer. Taken together, the results suggest that RAD51 rs1801321 polymorphism may be involved in the etiology of breast cancer in the Saudi females; however, further studies are necessary to confirm this relation.”0.95saudi_context_rules_v1