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5 records shown · first 60Preliminary investigation of MMP8 (rs11225395) and MMP9 (rs3787268) polymorphisms association with breast cancer risk in pashtun women of Pakistan.
PMID 39361067 | DOI 10.1007/s11033-024-09968-7 · Molecular biology reports · 2024 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs3787268 | “Preliminary investigation of MMP8 (rs11225395) and MMP9 (rs3787268) polymorphisms association with breast cancer risk in pashtun women of Pakistan.” | 0.90 | hgvs_regex_v1 |
| gene | MMP8 | “Preliminary investigation of MMP8 (rs11225395) and MMP9 (rs3787268) polymorphisms association with breast cancer risk in pashtun women of Pakistan.” | 0.98 | hgnc_dict_v1 |
| gene | MMP9 | “Preliminary investigation of MMP8 (rs11225395) and MMP9 (rs3787268) polymorphisms association with breast cancer risk in pashtun women of Pakistan.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Preliminary investigation of MMP8 (rs11225395) and MMP9 (rs3787268) polymorphisms association with breast cancer risk in pashtun women of Pakistan.” | 0.98 | phenotype_alias_lexicon_v2 |
Functionally significant polymorphisms of the MMP9 gene are associated with primary open-angle glaucoma in the population of Russia.
PMID 35254145 | DOI 10.1177/11206721221083722 · European journal of ophthalmology · 2022 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs3787268 | “Allele А*rs3787268 of MMP9 was associated with the low intraocular pressure in the POAG patients (βcov = -0.176 - -0.272), and so were haplotypes AA [rs17576-rs3787268] (βcov = -0.577) and AAC [rs17576-rs3787268- rs2250889] (βcov = -0.742) of the same gene, whereas allele 2G*rs1799750 of MMP1 was associated with the earlier onset of the disease (βcov = -0.112 - -0.218).” | 0.90 | hgvs_regex_v1 |
| gene | MMP9 | “Functionally significant polymorphisms of the MMP9 gene are associated with primary open-angle glaucoma in the population of Russia.” | 0.98 | hgnc_dict_v1 |
| gene | MMP1 | “PURPOSE: The aim of this study was to investigate the role of functionally significant loci of the matrix metalloproteinases genes 1, 3, 9 (MMP1, MMP3, and MMP9) in the development of primary open-angle glaucoma (POAG) in Caucasians of the Central region of Russia.” | 0.98 | hgnc_dict_v1 |
| gene | MMP3 | “PURPOSE: The aim of this study was to investigate the role of functionally significant loci of the matrix metalloproteinases genes 1, 3, 9 (MMP1, MMP3, and MMP9) in the development of primary open-angle glaucoma (POAG) in Caucasians of the Central region of Russia.” | 0.98 | hgnc_dict_v1 |
Association of the functionally significant polymorphisms of the MMP9 gene with H. pylori-positive gastric ulcer in the Caucasian population of Central Russia.
PMID 34492072 | PMCID PMC8423286 | DOI 10.1371/journal.pone.0257060 · PloS one · 2021 · 15 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs3787268 | “Ten SNPs of the MMP1 (rs1799750), MMP2 (rs243865), MMP3 (rs679620), MMP8 (rs1940475), and MMP9 (rs3918242, rs3918249, rs3787268, rs17576, rs17577, and rs2250889) genes were considered for association with GU using multiple logistic regression.” | 0.90 | hgvs_regex_v1 |
| gene | MMP9 | “Association of the functionally significant polymorphisms of the MMP9 gene with H. pylori-positive gastric ulcer in the Caucasian population of Central Russia.” | 0.98 | hgnc_dict_v1 |
| gene | MMP1 | “Ten SNPs of the MMP1 (rs1799750), MMP2 (rs243865), MMP3 (rs679620), MMP8 (rs1940475), and MMP9 (rs3918242, rs3918249, rs3787268, rs17576, rs17577, and rs2250889) genes were considered for association with GU using multiple logistic regression.” | 0.98 | hgnc_dict_v1 |
| gene | MMP2 | “Ten SNPs of the MMP1 (rs1799750), MMP2 (rs243865), MMP3 (rs679620), MMP8 (rs1940475), and MMP9 (rs3918242, rs3918249, rs3787268, rs17576, rs17577, and rs2250889) genes were considered for association with GU using multiple logistic regression.” | 0.98 | hgnc_dict_v1 |
Novel Data about Association of the Functionally Significant Polymorphisms of the MMP9 Gene with Exfoliation Glaucoma in the Caucasian Population of Central Russia.
PMID 33099542 | PMCID PMC8259063 | DOI 10.1159/000512507 · Ophthalmic research · 2021 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs3787268 | “The participants were genotyped at 8 functionally significant polymorphisms of the MMP genes (rs3918242, rs3918249, rs17576, rs3787268, rs2250889, rs17577 MMP9, rs679620 MMP3, and rs1799750 MMP1).” | 0.90 | hgvs_regex_v1 |
| gene | MMP9 | “Novel Data about Association of the Functionally Significant Polymorphisms of the MMP9 Gene with Exfoliation Glaucoma in the Caucasian Population of Central Russia.” | 0.98 | hgnc_dict_v1 |
| gene | MMP1 | “AIM: This study aimed to investigate the role of functionally significant polymorphisms of the MMP1, MMP3, and MMP9 genes in the development of exfoliation glaucoma (XFG) in the Caucasian population of Central Russia.” | 0.98 | hgnc_dict_v1 |
| gene | MMP3 | “AIM: This study aimed to investigate the role of functionally significant polymorphisms of the MMP1, MMP3, and MMP9 genes in the development of exfoliation glaucoma (XFG) in the Caucasian population of Central Russia.” | 0.98 | hgnc_dict_v1 |
Functionally significant polymorphisms of the MMP-9 gene are associated with peptic ulcer disease in the Caucasian population of Central Russia.
PMID 34188075 | PMCID PMC8241834 | DOI 10.1038/s41598-021-92527-y · Scientific reports · 2021 · 5 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs3787268 | “Allele G of the rs17576 MMP-9 locus conferred a higher risk for PUD (ORadj = 1.31, pperm = 0.016), haplotype AACG of loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene decreased risk for PUD (ORadj = 0.17, pperm = 0.003).” | 0.90 | hgvs_regex_v1 |
| variant | rs17576 | “Allele G of the rs17576 MMP-9 locus conferred a higher risk for PUD (ORadj = 1.31, pperm = 0.016), haplotype AACG of loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene decreased risk for PUD (ORadj = 0.17, pperm = 0.003).” | 0.90 | hgvs_regex_v1 |
| variant | rs2250889 | “Allele G of the rs17576 MMP-9 locus conferred a higher risk for PUD (ORadj = 1.31, pperm = 0.016), haplotype AACG of loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene decreased risk for PUD (ORadj = 0.17, pperm = 0.003).” | 0.90 | hgvs_regex_v1 |
| variant | rs17577 | “Allele G of the rs17576 MMP-9 locus conferred a higher risk for PUD (ORadj = 1.31, pperm = 0.016), haplotype AACG of loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene decreased risk for PUD (ORadj = 0.17, pperm = 0.003).” | 0.90 | hgvs_regex_v1 |