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2 records shown · first 60Polymorphism Analysis as Biomarker in Genes AIRE, CD40, HLA-DRB1 and TRAF1/C5 SNPs in Rheumatoid Arthritis Patients.
PMID 40696799 | DOI 10.1111/iji.70007 · International journal of immunogenetics · 2025 · 10 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs4810485 | “The main objective of the study was to determine the association of genes AIRE (rs2075876), CD40 (rs4810485), HLA-DRB1 (rs6457617) and TRAF1/C5 (rs10818488) polymorphisms with rheumatoid arthritis (RA) from the population of Pakistan.” | 0.90 | hgvs_regex_v1 |
| gene | AIRE | “Polymorphism Analysis as Biomarker in Genes AIRE, CD40, HLA-DRB1 and TRAF1/C5 SNPs in Rheumatoid Arthritis Patients.” | 0.98 | hgnc_dict_v1 |
| gene | CD40 | “Polymorphism Analysis as Biomarker in Genes AIRE, CD40, HLA-DRB1 and TRAF1/C5 SNPs in Rheumatoid Arthritis Patients.” | 0.98 | hgnc_dict_v1 |
| gene | HLA-DRB1 | “Polymorphism Analysis as Biomarker in Genes AIRE, CD40, HLA-DRB1 and TRAF1/C5 SNPs in Rheumatoid Arthritis Patients.” | 0.98 | hgnc_dict_v1 |
A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.
PMID 35107652 | DOI 10.1007/s10067-021-05998-9 · Clinical rheumatology · 2022 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs48104850 | “METHODS: IRAK-1 rs3027898, IRAK-2 rs3844283, IRAK-2 rs708035, IFIH1 rs1990760, CD40 rs48104850, TNFAIP3 rs2230926, and miR146-a rs2910164 were genotyped in 176 adult RA patients.” | 0.90 | hgvs_regex_v1 |
| variant | rs4810485 | “Among all the SNPs assessed, only CD40 rs4810485 was found to be associated with reduced TF Z score with the CD40 rs4810485 T allele protecting against reduced TF Z score (OR = 0.40, 95% CI = 0.23-0.68, p = 0.0005).” | 0.90 | hgvs_regex_v1 |
| gene | CD40 | “A CD40 variant is associated with systemic bone loss among patients with rheumatoid arthritis.” | 0.98 | hgnc_dict_v1 |
| gene | IFIH1 | “METHODS: IRAK-1 rs3027898, IRAK-2 rs3844283, IRAK-2 rs708035, IFIH1 rs1990760, CD40 rs48104850, TNFAIP3 rs2230926, and miR146-a rs2910164 were genotyped in 176 adult RA patients.” | 0.98 | hgnc_dict_v1 |