Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
Publications
2 records shown · first 60The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection.
PMID 29947302 | DOI 10.1080/09674845.2018.1492186 · British journal of biomedical science · 2018 · 11 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs5743312 | “RESULTS: Carriage of the C allele in three SNPs of TLR3 (rs3775290, rs3775291, and rs5743312), the C allele in TLR7 (rs3853839) in females only, and the C allele in TLR8 (rs3764879) in males only were significantly higher in SVC group than CHC group (P < 0.001), while carriage of the T allele in TLR7 (rs179008) in females only and the A allele in TLR8 (rs3764880) in both males and females were significantly higher in CHC infection more than SVC group (P < 0.001).” | 0.90 | hgvs_regex_v1 |
| gene | TLR3 | “We hypothesized that one or more variant(s) of TLR3, TLR7 and TLR8 are associated with different outcomes of HCV infection.” | 0.98 | hgnc_dict_v1 |
| gene | TLR7 | “We hypothesized that one or more variant(s) of TLR3, TLR7 and TLR8 are associated with different outcomes of HCV infection.” | 0.98 | hgnc_dict_v1 |
| gene | TLR8 | “We hypothesized that one or more variant(s) of TLR3, TLR7 and TLR8 are associated with different outcomes of HCV infection.” | 0.98 | hgnc_dict_v1 |
Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients.
PMID 22825813 | DOI 10.1002/jmv.23271 · Journal of medical virology · 2012 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs5743312 | “A total of 707 patients and 600 uninfected controls were examined for different parameters including the nine SNPs (rs5743311, rs5743312, rs1879026, rs5743313, rs5743314, rs5743315, rs111611328, rs78726532 and a newly identified SNP located at position 184322913 of chr4).” | 0.90 | hgvs_regex_v1 |
| gene | TLR3 | “TLR3 is part of the innate immune system that recognizes double-stranded RNA (dsRNA) and provides early immune response to exogenous antigens.” | 0.98 | hgnc_dict_v1 |
| phenotype | hepatitis B | “Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | hepatocellular carcinoma | “Hepatitis B virus (HBV) is the major causative agent of chronic liver complications including cirrhosis and hepatocellular carcinoma (HCC).” | 0.98 | phenotype_alias_lexicon_v2 |