Advanced search
Combine gene, variant, phenotype, region and year filters
Every result shows the extracted entities next to the sentences that support them; rows for the searched entities come first.
Transparent by designEvery result links extracted entities to its source sentence and publication identifier.
Knowledge-base search
Publications
2 records shown · first 60Polymorphisms of the filaggrin gene are associated with atopic dermatitis in the Caucasian population of Central Russia.
PMID 35092857 | DOI 10.1016/j.gene.2022.146219 · Gene · 2022 · 12 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs61816761 | “In total ten SNPs of the gene (rs61816761, rs12130219, rs77199844, rs558269137, rs4363385, rs12144049, rs471144, rs6661961, rs10888499, rs3126085), their haplotypes and interlocus interactions were analyzed using logistic regression.” | 0.90 | hgvs_regex_v1 |
| gene | FLG | “Association of the filaggrin (FLG) gene with atopic dermatitis (AD) in Caucasians from Central Russia was studied in the sample of 700 patients and 612 controls.” | 0.98 | hgnc_dict_v1 |
| phenotype | atopic dermatitis | “Polymorphisms of the filaggrin gene are associated with atopic dermatitis in the Caucasian population of Central Russia.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs12130219 | “In total ten SNPs of the gene (rs61816761, rs12130219, rs77199844, rs558269137, rs4363385, rs12144049, rs471144, rs6661961, rs10888499, rs3126085), their haplotypes and interlocus interactions were analyzed using logistic regression.” | 0.90 | hgvs_regex_v1 |
Filaggrin gene polymorphisms are associated with atopic dermatitis in women but not in men in the Caucasian population of Central Russia.
PMID 34882715 | PMCID PMC8659355 | DOI 10.1371/journal.pone.0261026 · PloS one · 2021 · 9 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs61816761 | “RESULTS: Significant associations were identified between seven SNPs of the FLG gene (rs12130219, rs61816761, rs558269137, rs12144049, rs3126085, rs471144, rs6661961) and AD in females: rs12144049 was associated independent individually (for allele C OR = 1.71, 95%Сl 1.19-2.46, рperm = 0.004 and OR = 1.76, 95%Сl 1.18-2.63, рperm = 0.006 according to the additive and dominant genetic models, respectively) and seven SNPs of the FLG gene within 14 haplotypes.” | 0.90 | hgvs_regex_v1 |
| gene | FLG | “BACKGROUND AND PURPOSE: This study aimed to analyze the gender-specific association of the filaggrin (FLG) gene polymorphisms with atopic dermatitis (AD) in Caucasians from the central region of Russia.” | 0.98 | hgnc_dict_v1 |
| phenotype | atopic dermatitis | “Filaggrin gene polymorphisms are associated with atopic dermatitis in women but not in men in the Caucasian population of Central Russia.” | 0.98 | phenotype_alias_lexicon_v2 |
| variant | rs12130219 | “RESULTS: Significant associations were identified between seven SNPs of the FLG gene (rs12130219, rs61816761, rs558269137, rs12144049, rs3126085, rs471144, rs6661961) and AD in females: rs12144049 was associated independent individually (for allele C OR = 1.71, 95%Сl 1.19-2.46, рperm = 0.004 and OR = 1.76, 95%Сl 1.18-2.63, рperm = 0.006 according to the additive and dominant genetic models, respectively) and seven SNPs of the FLG gene within 14 haplotypes.” | 0.90 | hgvs_regex_v1 |