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Biomarker Variants of Dopamine Receptor Genes Influence the Binding Interaction Between Dopamine Receptor and Risperidone.

PMID 42052100 | PMCID PMC13117852 | DOI 10.2147/DDDT.S587705 · Drug design, development and therapy · 2026 · 12 validated mentions
TypeEntitySource evidenceConfidenceExtractor
variantrs866976053“RESULTS: The analysis predicted the most deleterious nsSNPs in each dopamine receptor: rs759268810 in DRD1, rs866976053 in DRD2, rs1274871399 in DRD3, rs745604469 in DRD4, and rs778635010 in DRD5.”0.90hgvs_regex_v1
geneDRD1“METHODS: Using state-of-the-art tools, the current study designed to predict the most deleterious SNPs of the five (DRD1, DRD2, DRD3, DRD4 and DRD5) dopamine receptors genes, and their impact on the function and structure of dopamine receptor protein and the binding with risperidone.”0.98hgnc_dict_v1
geneDRD2“METHODS: Using state-of-the-art tools, the current study designed to predict the most deleterious SNPs of the five (DRD1, DRD2, DRD3, DRD4 and DRD5) dopamine receptors genes, and their impact on the function and structure of dopamine receptor protein and the binding with risperidone.”0.98hgnc_dict_v1
geneDRD3“METHODS: Using state-of-the-art tools, the current study designed to predict the most deleterious SNPs of the five (DRD1, DRD2, DRD3, DRD4 and DRD5) dopamine receptors genes, and their impact on the function and structure of dopamine receptor protein and the binding with risperidone.”0.98hgnc_dict_v1