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1 records shown · first 60Molecular Effect of Variants in Toll-like Receptor 4 Gene in Saudi Patients with Type 2 Diabetes Mellitus.
PMID 37830554 | PMCID PMC10571932 | DOI 10.3390/cells12192340 · Cells · 2023 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs11536889 | “We investigated the relationship between rs11536889, rs4986790, and rs4986791 SNPs in the TLR4 gene and T2DM in the Saudi population; 105 patients with T2DM and 105 healthy controls were analyzed.” | 0.90 | hgvs_regex_v1 |
| gene | TLR4 | “Single-nucleotide polymorphisms (SNPs) in the Toll-like receptor 4 (TLR4) gene have been documented in type 2 diabetes mellitus (T2DM) and other diseases in the Saudi population.” | 0.98 | hgnc_dict_v1 |
| gene | DBP | “Analysis of variance showed that waist (p = 0.0005) and hip circumferences (p = 0.002) in rs4986790 and rs4986791 SNPs, in SBP (p = 0.001), DBP (p = 0.002), and HDLc levels (p = 0.003), were associated with T2DM subjects.” | 0.98 | hgnc_dict_v1 |
| phenotype | diabetes mellitus | “Molecular Effect of Variants in Toll-like Receptor 4 Gene in Saudi Patients with Type 2 Diabetes Mellitus.” | 0.98 | phenotype_alias_lexicon_v2 |