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A preliminary study of cytokine gene polymorphism effects on Saudi patients with colorectal cancer.

PMID 33294886 | PMCID PMC7841582 | DOI 10.15537/smj.2020.12.25543 · Saudi medical journal · 2020 · 8 validated mentions
TypeEntitySource evidenceConfidenceExtractor
variantrs17855750“OBJECTIVE: To determine the possible associations of polymorphisms in interleukin (IL)-8 (rs4073 T/A), IL-10 (rs1800896 A/G), IL-22 (rs1179251 C/G and rs2227485 C/T), IL-27 (rs17855750 T/G), and transforming growth factor beta 1 (TGFß1) (rs1800469 C/T) with colorectal cancer (CRC) susceptibility in Saudi patients.”0.90hgvs_regex_v1
phenotypecolorectal cancer“A preliminary study of cytokine gene polymorphism effects on Saudi patients with colorectal cancer.”0.98phenotype_alias_lexicon_v2
populationSaudi Arabia, Riyadh“A preliminary study of cytokine gene polymorphism effects on Saudi patients with colorectal cancer. OBJECTIVE: To determine the possible associations of polymorphisms in interleukin (IL)-8 (rs4073 T/A), IL-10 (rs1800896 A/G), IL-22 (rs1179251 C/G and rs2227485 C/T), IL-27 (rs17855750 T/G), and transforming growth factor beta 1 (TGFß1) (rs1800469 C/T) with colorectal cancer (CRC) susceptibility in Saudi patients. METHODS: The case-control study was carried out between July 2019 and January 2020 in King Khaled University Hospital, Riyadh, Saudi Arabia. A total of 70 patients with CRC and 70 healthy controls were included in the study.”0.95saudi_context_rules_v1
variantrs4073“OBJECTIVE: To determine the possible associations of polymorphisms in interleukin (IL)-8 (rs4073 T/A), IL-10 (rs1800896 A/G), IL-22 (rs1179251 C/G and rs2227485 C/T), IL-27 (rs17855750 T/G), and transforming growth factor beta 1 (TGFß1) (rs1800469 C/T) with colorectal cancer (CRC) susceptibility in Saudi patients.”0.90hgvs_regex_v1