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1 records shown · first 60TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study.
PMID 36465847 | PMCID PMC9715634 | DOI 10.1016/j.jsps.2022.07.015 · Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs201857310 | “The association of two variants, the rs201857310, and rs7530810, in the TSH-β gene with thyroid cancer risk as well as thyroxine dose, were evaluated.” | 0.90 | hgvs_regex_v1 |
| phenotype | thyroid cancer | “TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study. This study aimed to evaluate the role of the TSH-β polymorphism in thyroid cancer in a Saudi cohort. METHODS: A prospective case-control study was conducted on 507 patients with differentiated thyroid carcinoma and compared them with 560 controls of Saudi origin. CONCLUSIONS: Our findings indicate that the TSH-β gene could have a role in the pathogenesis of differentiated thyroid carcinoma in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| variant | rs7530810 | “The association of two variants, the rs201857310, and rs7530810, in the TSH-β gene with thyroid cancer risk as well as thyroxine dose, were evaluated.” | 0.90 | hgvs_regex_v1 |