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1 records shown · first 60Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.
PMID 41011233 | PMCID PMC12472897 | DOI 10.3390/ph18091365 · Pharmaceuticals (Basel, Switzerland) · 2025 · 4 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs2231137 | “Regarding the rs2231137 polymorphism, the CC, CT, and TT genotype frequency were 91%, 7%, and 2%, respectively.” | 0.90 | hgvs_regex_v1 |
| gene | ABCG2 | “Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.” | 0.98 | hgnc_dict_v1 |
| phenotype | rheumatoid arthritis | “Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “Association of ABCG2 Polymorphisms with Methotrexate Efficacy and Toxicity in Saudi Rheumatoid Arthritis Patients. Therefore, this study aimed to investigate the associations between the polymorphisms in the ABC subfamily G member 2 (ABCG2) gene and MTX effectiveness/toxicity in Saudi Arabia RA patients.” | 0.95 | saudi_context_rules_v1 |