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Genetic variants of CYP2C19 and CYP2C18 and their clinical implications in the Saudi population.

PMID 41908226 | PMCID PMC13018941 | DOI 10.1016/j.jtumed.2026.03.003 · Journal of Taibah University Medical Sciences · 2026 · 10 validated mentions
TypeEntitySource evidenceConfidenceExtractor
variantrs4917623“Five detected variants had high frequencies: rs7067866, rs7916649, rs4917623, rs12248560, and rs11188072.”0.90hgvs_regex_v1
geneCYP2C19“Genetic variants of CYP2C19 and CYP2C18 and their clinical implications in the Saudi population.”0.98hgnc_dict_v1
geneCYP2C18“Genetic variants of CYP2C19 and CYP2C18 and their clinical implications in the Saudi population.”0.98hgnc_dict_v1
populationSaudi Arabia“Genetic variants of CYP2C19 and CYP2C18 and their clinical implications in the Saudi population. BACKGROUND: At least 500 genetic polymorphisms associated with the CYP2C19 and CYP2C18 enzymes have been identified, yet few polymorphisms have been measured in the Saudi population. Blood samples from 374 Saudi adults were genotyped. Tens of previously unmeasured CYP2C19 and CYP2C18 variants were identified in the Saudi population.”0.95saudi_context_rules_v1