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2 records shown · first 60Novel Associations between BRCA1 Variants C.181 T>G (Rs28897672) and Ovarian Crisk in Saudi Females.
PMID 30820179 | PMCID PMC6298454 | DOI 10.2478/jomb-2018-0037 · Journal of medical biochemistry · 2019 · 7 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs799917 | “The variants investigated included c.871 T>C (rs799917), c.1040 G>A (rs4986852), c.181 T>G (rs28897672) in BRCA1 gene.” | 0.90 | hgvs_regex_v1 |
| gene | BRCA1 | “Novel Associations between BRCA1 Variants C.181 T>G (Rs28897672) and Ovarian Crisk in Saudi Females.” | 0.98 | hgnc_dict_v1 |
| gene | TG | “The genotype TG was significantly protective (OR = 0.36, p value = 0.024).” | 0.98 | hgnc_dict_v1 |
| phenotype | ovarian cancer | “This study was designed to determine the frequency of three single nucleotide polymorphisms (SNPs) variants in BRCA1 gene and BRCA1 expression in Saudi females with ovarian cancer.” | 0.98 | phenotype_alias_lexicon_v2 |
Lack of association of BRCA1 and BRCA2 variants with breast cancer in an ethnic population of Saudi Arabia, an emerging high-risk area.
PMID 24289560 | DOI 10.7314/apjcp.2013.14.10.5671 · Asian Pacific journal of cancer prevention : APJCP · 2013 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs799917 | “TaqMan based Real Time Polymerase chain reaction genotyping assays were used to determine the frequency of single nucleotide polymorphisms in BRCA1 (rs799917) and BRCA2 (rs144848) in a group of 100 breast cancer patients and unaffected age matched controls of Saudi Arabian origin.” | 0.90 | hgvs_regex_v1 |
| gene | BRCA1 | “Lack of association of BRCA1 and BRCA2 variants with breast cancer in an ethnic population of Saudi Arabia, an emerging high-risk area.” | 0.98 | hgnc_dict_v1 |
| gene | BRCA2 | “Lack of association of BRCA1 and BRCA2 variants with breast cancer in an ethnic population of Saudi Arabia, an emerging high-risk area.” | 0.98 | hgnc_dict_v1 |
| phenotype | breast cancer | “Lack of association of BRCA1 and BRCA2 variants with breast cancer in an ethnic population of Saudi Arabia, an emerging high-risk area.” | 0.98 | phenotype_alias_lexicon_v2 |